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Country: France
5 Projects, page 1 of 1
  • Funder: European Commission Project Code: 737954
    Overall Budget: 2,760,690 EURFunder Contribution: 2,200,040 EUR

    Great advances were made by SISCERA partners in the development of the world’s first ceramics showing transformation induced plasticity and perfect predictability. These specifically designed materials were the main research results of the LongLife FP7 project and will be brought to market via SISCERA. The LONGLIFE material is based on a novel, highly biocompatible ceramic coupled with a specific surface modification, procuring enhanced osseointegration to implants. Its reliability and mechanical performances have been validated in accordance to the relevant standards. The core objective of SISCERA (Smart Innovations from Safe CERAmics) is to prepare market penetration by the end of 2019 of the first commercial application of this revolutionary ceramic. This new type of material can serve industries such as biomedical (implants, bone saws, prostheses), automotive & fuel cell. DMC will commercialise the material for several applications: (i) ceramic bars (for Anthogyr and biomedical customers), (ii) centering pins for car body welding (for existing automotive industry customers), and (iii) positioning devices for handling robots (for existing industrial customers). SWEREA will apply its surface modification process to facilitate production of solid-oxide fuel cells. The partners have carefully analysed the different markets and have determined that the most strategic initial biomedical application is the dental implant. This market is expected to grow annually by 6-8% during the next years, to 5.4 Billion € by 2020. Ceramics are entering the market as implant materials, but their use is still limited by inadequate toughness and osseointegration. The SISCERA consortium has the ideal material and expertise to provide the first dental implant fully meeting patient needs. The current FTI project will allow partners to obtain clinical and biocompatibility validation of the implant while also penetrating the market with promising applications in other industries.

  • Funder: European Commission Project Code: 101091669
    Overall Budget: 4,708,220 EURFunder Contribution: 4,708,220 EUR

    Peri-implant infections are a devastating complication of dental implants, occurring in approximately 20% of all patients, that can ultimately lead to implant instability and loss. Considering this high prevalence rate and the lack of predictive treatments in severe cases, prevention of peri-implantitis has become a major challenge in clinical dentistry. NOMAD will develop innovative biomaterial approaches for dental implants, from TRL3 to TRL5. Various functionalised implant coatings for titanium and zirconia implant surfaces will reduce the risk of infection (and associated inflammation), improve soft-tissue sealing at the gum line, and promote osseointegration. A further innovation are multi-material crowns and abutments using additive manufacturing combined with grafting of nanotubes, enabling controlled release of prebiotic as well as antimicrobial compounds in response to bacterial adhesion at the onset of infection (i.e. smart conditional release). A combination of these approaches will be employed in the final product to provide a customisable, all-round solution focusing on crown, abutment and/or fixture for prevention of peri-implantitis. Advanced in vitro testing using complex cell co-cultures in bioreactor systems, and biomechanical stability tests will enable selecting the most promising biomaterials for testing in relevant in vivo models. These results will enable rapid progression to first-in-human studies of new biomaterials after the project. A cost-benefit and regulatory analysis will be performed and an innovation management strategy will develop a roadmap for commercialisation. The NOMAD consortium includes a major dental implant manufacturer, academic groups, SMEs working on biomaterials innovation and a specialist innovation company. The project is a major opportunity for enhancing EU competitiveness in biomaterials and inter-sector technology transfer.

  • Funder: European Commission Project Code: 280741
  • Funder: European Commission Project Code: 861046
    Overall Budget: 4,029,970 EURFunder Contribution: 4,029,970 EUR

    Implant-associated infections, commonly caused by biofilm-forming bacteria, are highly problematic for the patient, the healthcare system, and society. BIOREMIA will recruit 15 doctoral students (ESRs) and provide a highly inter-disciplinary joint research & training programme focused on the key issues that determine the future antibacterial biomaterials and technologies for orthopaedic and dental applications. BIOREMIA links 7 academic and 4 non-academic beneficiaries as well as 6 partners from 11 European countries (Germany, Austria, Greece, Sweden, UK, Spain, Italy, France, Switzerland, Ireland and the Netherlands) and the USA. The ESRs will be supervised and trained by world-class academic and industrial organisations, combining technical knowledge with hands-on training in state-of-the-art research projects. BIOREMIA training program will include face-to-face and online scientific courses in biomaterials & surface engineering, biotechnology,nanotechnology, implant manufacturing, biochemistry, microbiology and biofilm. This will be complemented by education in transferable skills such as entrepreneurship, management, IPR, communication etc. useful for getting an innovation-oriented mind-set of young researchers. Participating in BIOREMIA will make PhD students highly attractive for employers and open up doors for their successful careers in research, regulation, consulting, industry and the healthcare system. They will be experts for the better assessment of the antibacterial functionality of materials and surfaces and for delivering successful strategies for the medical device industry and the healthcare system. The strong involvement of the industrial sector will provide the ESRs with a holistic perspective on career opportunities. Beyond the trained researchers, this network will produce innovative materials and technologies that will enhance the productivity of European industry and improve the well-being of European citizens by minimizing implant-associated infection rates.

  • Funder: European Commission Project Code: 734342
    Overall Budget: 877,500 EURFunder Contribution: 877,500 EUR

    Additive manufacturing (AM) technologies and overall numerical fabrication methods have been recognized by stakeholders as the next industrial revolution bringing customers’ needs and suppliers’ offers closer. It cannot be dissociated to the present trends in increased virtualization, cloud approaches and collaborative developments (i.e. sharing of resources). AM is likely to be one good option paving the way to Europe re-industrialization and increased competitiveness. AMITIE will reinforce European capacities in the AM field applied to ceramic-based products. Through its extensive programme of transnational and intersectoral secondments, AMITIE will promote fast technology transfer and enable as well training of AM experts from upstream research down to more technical issues. This will provide Europe with specialists of generic skills having a great potential of knowledge-based careers considering present growing needs for AM industry development. To do that, AMITIE brings together leading academic and industrial European players in the fields of materials science/processes, materials characterizations, AM technologies and associated numerical simulations, applied to the fabrication of functional and/or structural ceramic-based materials for energy/transport, and ICTs applications, as well as biomaterials. Those players will develop a new concept of smart factory for the future based on 3D AM technologies (i.e. powder bed methods, robocasting, inkjet printing, stereolithography, etc.) and their possible hybridization together or with subtractive technologies (e.g. laser machining). It will allow for the production of parts whose dimensions, shapes, functionality and assembly strategies may be tailored to address today’s key technological issues of the fabrication of high added value objects following a fully-combinatorial route. This is expected to lead to a new paradigm for production of multiscale, multimaterial and multifunctional components and systems


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