organization

University of Oxford

1,707 projects, page 1 of 342
  • project . 2020 - 2021
    Funder: WT Project Code: 220557
    Funder Contribution: 100,546 GBP
    Open Access mandate for Publications
    Partners: University of Oxford

    Blood culture (BC), the core sample for antimicrobial resistance surveillance, is recommended to be sampled from all sepsis patients prior to administration of antibiotics. However, BC sampling rates are lower than recommended in both high-income countries (HICs) and lo...

  • project . 2021 - 2022
    Funder: WT Project Code: 222305
    Funder Contribution: 1,120,860 GBP
    Open Access mandate for Publications
    Partners: University of Oxford

    Understanding the nature, effectiveness and durability of the human immune response to SARS CoV2 is crucial for vaccine development and effective public health management. We are beginning to understand the pattern and kinetics of the humoral response to natural infecti...

  • project . 2020 - 2025
    Funder: WT Project Code: 220171
    Funder Contribution: 1,153,490 GBP
    Open Access mandate for Publications
    Partners: University of Oxford

    Host and pathogen genetic variations are major causes of clinical outcomes of infectious diseases. Traditionally, genetic studies of infectious diseases have sought to explain between-individual variation in disease by assessing genetic factors separately in humans or p...

  • project . 2021 - 2025
    Funder: WT Project Code: 220452
    Funder Contribution: 300,000 GBP
    Open Access mandate for Publications
    Partners: University of Oxford

    Efficient T cell responses rely on heterogeneity, characterized by the rise of effector and memory cells. Autophagy, responsible for homeostatic degradation and recycling of cell cargo, is crucial for T cell differentiation. Upon ageing, autophagy is impaired, which is ...

  • project . 2021 - 2025
    Funder: WT Project Code: 220679
    Funder Contribution: 1,304,620 GBP
    Open Access mandate for Publications
    Partners: University of Oxford

    Viral fusion proteins are important targets for vaccine-induced neutralising antibody. Structure-guided design of such antigens in pre-fusion conformation has created leading vaccine candidates against viruses with Class I and II fusion proteins, such as respiratory syn...

1,707 projects, page 1 of 342
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