Filters (2 )
Download Results
82,062 research outcomes, page 1 of 8,207
  • publication . Preprint . Article . 2020
    Open Access English
    Authors:
    Chihao Zhang; Shao-Jung Hsu; Shao-Jung Hsu; Yasuko Iwakiri; Seong-il Lee; Teruo Utsumi; Matthew McConnell; Jain Jeong;
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | Hemodynamics and hepatic ... (1R01DK117597-01), NIH | Investigative Training in... (5T32DK007356-29)

    <jats:title>Abstract</jats:title><jats:sec><jats:title>Background and aims</jats:title><jats:p>Hepatic encephalopathy (HE) is a serious neurological complication in patients with liver cirrhosis. Nothing is known about the role of the meningeal lymphatic system in HE. W...

  • publication . Other literature type . Preprint . 2019
    Open Access
    Authors:
    Hiroki Uchida; Keri Callegari; Akira Ito; Yun-Kyoung Lee; Jenny Xiang; Teresa Sanchez; Sabyasachi Dash; Tuo Zhang;
    Publisher: bioRxiv
    Project: NIH | Sphingolipid Signaling in... (5R01HL094465-04)

    <jats:title>ABSTRACT</jats:title><jats:p>Increasing evidence implicates cerebral microvascular dysfunction in the pathophysiology of numerous central nervous system pathologies, including stroke. Understanding the molecular alterations in cerebral microvessels in these ...

  • publication . Preprint . Article . Other literature type . 2019
    Open Access
    Authors:
    Choi, Jae Young; Purugganan, Michael; Stacy, Elizabeth A.;
    Publisher: Cold Spring Harbor Laboratory
    Project: NSF | CREST Center in Tropical ... (0833211), NSF | CAREER: Characterizing re... (0954274)

    <jats:title>Abstract</jats:title><jats:p>A long-standing goal of evolutionary biology is to understand the mechanisms underlying the formation of species. Of particular interest is whether or not speciation can occur in the presence of gene flow and without a period of ...

  • publication . Preprint . Other literature type . Article . 2017
    Open Access English
    Authors:
    Dieter Egli; Michael Kosicki; Allan Bradley; Maria Jasin; Michael V. Zuccaro; George M. Church;
    Publisher: Cold Spring Harbor Laboratory

    Many human diseases have an underlying genetic component. The development and application of methods to prevent the inheritance of damaging mutations through the human germline could have significant health benefits, and currently include preimplantation genetic diagnos...

  • publication . Preprint . 2017
    Open Access English
    Authors:
    Johannes Birgmeier; Cole A. Deisseroth; Harendra Guturu; Alexander Ratner; Jonathan A. Bernstein; Karthik A. Jagadeesh; Maximilian Haeussler; Gill Bejerano; Christopher Ré; Aaron M. Wenger; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: WT | Wellcome Trust Sanger Ins... (098051)

    <jats:title>Abstract</jats:title><jats:p>The diagnosis of Mendelian disorders requires labor-intensive literature research. Our software system AMELIE (<jats:underline>A</jats:underline>utomatic <jats:underline>M</jats:underline>endelian <jats:underline>L</jats:underlin...

  • publication . Article . Preprint . 2019
    Open Access
    Authors:
    Molly Pruitt; Alexa F Iannitelli; Daniel Lustberg; L. Cameron Liles; Rachel P. Tillage; David Weinshenker;
    Publisher: Springer Science and Business Media LLC

    <jats:title>Abstract</jats:title><jats:sec><jats:title>Rationale</jats:title><jats:p>Obsessive-compulsive disorder (OCD) is characterized by repetitive behaviors exacerbated by stress. Many OCD patients do not respond to available pharmacotherapies, but neurosurgical ab...

  • publication . Preprint . 2019
    Open Access English
    Authors:
    Laurent Blanchoin; Laurent Blanchoin; Fabrice Senger; Manuel Théry; Manuel Théry; Amandine Pitaval; Laetitia Kurzawa; Hajer Ennomani;
    Publisher: Cold Spring Harbor Laboratory
    Project: EC | SPICY (310472), EC | AAA (741773)

    <jats:p>Cell and tissue morphogenesis depend on the production and spatial organization of tensional forces in the actin cytoskeleton. Actin network architecture is complex because it is made of distinct modules in which filaments adopt a variety of organizations. The a...

  • publication . Preprint . 2017
    Open Access
    Authors:
    Goudarzi, Hamid Reza; Nazari, Ali; Noofeli, Mojtaba; Samiani, Maedeh;
    Publisher: Cold Spring Harbor Laboratory

    <jats:title>Abstract</jats:title><jats:p>The venom of animals, including snakes, scorpions and spiders is a complex combination of proteins, peptides, and other biomolecules as well as some minerals. Among the biomolecules, some peptides prevent converting of angiotensi...

  • publication . Article . Preprint . 2017
    Open Access
    Authors:
    Ross, Caroline Jane; Nizami, Bilal; Glenister, Michael; Amamuddy, Olivier Sheik; Atılgan, Ali Rana; Atilgan, Ali Rana; Atılgan, Canan; Atilgan, Canan; Bishop, Özlem Taştan; Bishop, Ozlem Tastan;
    Publisher: Oxford University Press
    Project: NIH | H3ABioNet: informatics so... (5U24HG006941-07), NIH | H3ABioNet: a sustainable ... (3U41HG006941-02S2)

    <jats:title>Abstract</jats:title><jats:sec><jats:title>Summary</jats:title><jats:p>MODE-TASK, a novel software suite, comprises Principle Component Analysis, Multidimensional Scaling, and t-Distributed Stochastic Neighbor Embedding techniques using molecular dynamics tr...

  • publication . Preprint . 2019
    Open Access English
    Authors:
    Fuleah A. Razzaq; Eduardo Gonzalez-Moreira; Ying Wang; Qi Yuan; Min Li; Usama Riaz; Deirel Paz-Linares; Pedro A. Valdes-Sosa;
    Publisher: Cold Spring Harbor Laboratory

    Abstract In the resting state (closed or open eyes) electroencephalogram (EEG) and the magnetoencephalogram (MEG), rhythmic brain activity is very evident, typically the 10 Hz alpha rhythm. It has a topographic frequency spectral distribution that is, at first sight, qu...

82,062 research outcomes, page 1 of 8,207