Summary Human ALC1 is an oncogene-encoded chromatin-remodeling enzyme required for DNA repair that possesses a poly(ADP-ribose) (PAR)-binding macro domain. Its engagement with PARylated PARP1 activates ALC1 at sites of DNA damage, but the underlying mechanism remains un...

Abstract Background Access to food is a basic necessity, and food insecurity may impair the individual’s well-being and health. Self-rated health measurements have frequently been used to assess population health. Little is known, however, as to whether food security is...

Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer in the Nordic countries. Structural chromosomal rearrangements are a hallmark of ALL and represent key markers for diagnosis, risk stratification and prognosis. Nevertheless, a substantial proportion...

I dagens globala samhälle finns det stora möjligheter för företag att nå internationella marknader. Om företag väljer att expandera till dessa internationella marknader möts de av olika utmaningar. En av utmaningarna är hur de ska lyckas skapa förtroende till nya intern...