The knowledge of relaxation times is essential for understanding the biophysical mechanisms underlying contrast in magnetic resonance imaging. Quantitative experiments, while offering major advantages in terms of reproducibility, may benefit from simultaneous acquisitio...

Tumor xenografts in immunodeficient mice, while routinely used in cancer research, preclude studying interactions of immune and cancer cells or, if humanized by allogeneic immune cells, are of limited use for tumor-immunological questions. Here, we explore a novel way t...

Background: The formation of the East African Rift System has decisively influenced the distribution and evolution of tropical Africa's biota by altering climate conditions, by creating basins for large long-lived lakes, and by affecting the catchment and drainage direc...

The decaheme cytochrome MtrC from Shewanella oneidensis MR-1 immobilized on an ITO electrode displays unprecedented H2O2 reduction activity. Although MtrC showed lower peroxidase activity in solution compared to horseradish peroxidase, the ten heme cofactors enable exce...

Repeated exposure to thin beauty ideals is part of the daily routine. Exposure to thin ideals via mass media plays an important role in the development and maintenance of eating disorders (EDs), low self-esteem, depressive or anxious feelings in young females. It is imp...

ABSTRACT Ribosomal decoding is an essential process in every living cell. During protein synthesis the 30S ribosomal subunit needs to accomplish binding and accurate decoding of mRNAs. From mutational studies and high-resolution crystal structures nucleotides G530, A149...

AIMS To evaluate our proposed multivariate approach to identify patients who will develop sight-threatening diabetic retinopathy (STDR) within a 1-year screen interval, and explore the impact of simple stratification rules on prediction. MATERIALS AND METHODS A 7-year d...

A major challenge in aquaculture is finding nutrient resources that do not compete with human demand and do not threaten ecological sustainability. Single cell proteins, such as filamentous fungi and yeasts, have similar nutrient profiles to fish meal, grow fast under o...

Author summary Plasmodium vivax malaria presents challenges for malaria elimination distinct from those of the other human malarias. Patients become symptomatic at lower asexual parasitaemia, making it harder to diagnose, and its dormant stages in the liver give rise to...

Ocean circulation models do not generally exhibit equatorial deep jets (EDJs), even though EDJs are a recognised feature of the observed ocean circulation along the equator and they are thought to be important for tracer transport along the equator and even equatorial c...