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149,120 research outcomes, page 1 of 14,912
  • publication . Article . 2020
    Authors:
    Dana Stenger; Tanja A. Stief; Theresa Kaeuferle; Semjon Willier; Felicitas Rataj; Kilian Schober; Binje Vick; Ramin Lotfi; Beate Wagner; Thomas G. P. Grunewald; ...
    Persistent Identifiers
    Publisher: American Society of Hematology
    Project: EC | LeukaemiaTargeted (681524)

    Abstract Anti-CD19 chimeric antigen receptor (CAR) T cells showed significant antileukemic activity in B-precursor acute lymphoblastic leukemia (ALL). Allogeneic, HLA-mismatched off-the-shelf third-party donors may offer ideal fitness of the effector cells, but carry th...

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  • publication . Article . 1984
    Open Access
    Authors:
    Reimers, RC; Sutera, SP; Joist, JH;
    Persistent Identifiers
    Publisher: American Society of Hematology

    Abstract Evidence has been reported to indicate that red blood cells (RBCs) may potentiate platelet adherence and platelet aggregation (PAG) in different flow systems in vitro as well as hemostatic platelet plug formation in response to vascular injury. In this study, w...

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  • publication . Article . 2015
    Open Access
    Authors:
    Midori Nakagaki; Michael Barras; Cameron Curley; Jason Butler; Glen A Kennedy;
    Persistent Identifiers
    Publisher: American Society of Hematology

    Abstract Background: Despite routine antiemetic administration during conditioning for hematopoietic stem cell transplantation (HSCT), breakthrough chemotherapy induced nausea and vomiting (CINV) can still be problematic. Recent studies in solid tumor therapy have demon...

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  • publication . Article . Other literature type . 2008
    Open Access
    Authors:
    Caligiuri, Michael A.;
    Persistent Identifiers
    Publisher: American Society of Hematology

    Abstract Natural killer (NK) cells were discovered more than 30 years ago. NK cells are large granular lymphocytes that belong to the innate immune system because unlike T or B lymphocytes of the adaptive or antigen-specific immune system, NK cells do not rearrange T-ce...

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  • publication . Article . 2002
    Open Access
    Authors:
    Jaime O. Claudio; Esther Masih-Khan; Hongchang Tang; Jason Goncalves; Michael Voralia; Zhi Hua Li; Vincent Nadeem; Eva Cukerman; Ofelia Francisco-Pabalan; Choong Chin Liew; ...
    Persistent Identifiers
    Publisher: American Society of Hematology

    We have created a molecular resource of genes expressed in primary malignant plasma cells using a combination of cDNA library construction, 5' end single-pass sequencing, bioinformatics, and microarray analysis. In total, we identified 9732 nonredundant expressed genes....

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  • publication . Article . 2009
    Authors:
    Rachel B. Salit; Seth M. Steinberg; Daniel H. Fowler; Jeanne Odom; Kelly Bryant; Michael R. Bishop;
    Persistent Identifiers
    Publisher: American Society of Hematology

    Abstract Abstract 656 Reduced intensity allogeneic stem cell transplantation (RIST) is associated with decreased transplant-related mortality (TRM), broadening the pool of patients who could potentially benefit from allogeneic cellular therapy. However, RIST historicall...

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  • publication . Article . 2009
    Authors:
    Sunanda Basu; Hal E. Broxmeyer;
    Persistent Identifiers
    Publisher: American Society of Hematology

    Abstract 3616 Poster Board III-552 Despite being an excellent alternative to bone marrow or mobilized peripheral blood as a source of hematopoietic stem progenitor cells (HSPCs), the limiting factor to wider use of cord blood (CB) in transplantation is the 10-fold lower...

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  • publication . Other literature type . Article . 2014
    Open Access
    Authors:
    Tomomi Toubai; Guoqing Hou; Nathan Mathewson; Chen Liu; Ying Wang; Katherine Oravecz-Wilson; Emily Cummings; Corinne Rossi; Rebecca Evers; Yaping Sun; ...
    Persistent Identifiers
    Publisher: American Society of Hematology

    Activation of sialic-acid–binding immunoglobulin-like lectin-G (Siglec-G) by noninfectious damage-associated molecular patterns controls innate immune responses. However, whether it also regulates T-cell–mediated adaptive immune responses is not known. Graft-versus-host...

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  • publication . Article . 2006
    Open Access English
    Authors:
    Noria Harir; Christian Pecquet; Marc A. Kerenyi; Karoline Sonneck; Boris Kovacic; Rémy Nyga; Marie Brevet; Isabelle Dhennin; Valérie Gouilleux-Gruart; Hartmut Beug; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Country: France

    Abstract Persistent activation of Stat5 is frequently found in hematologic neoplasms. Studies conducted with constitutively active Stat5 mutants (Stat51*6 and cS5F) have shown that deregulated Stat5 activity promotes leukemogenesis. To investigate the oncogenic properti...

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  • publication . Article . 2015
    Open Access
    Authors:
    Barrans Sharon; Andrew Davies; Ming Wang; Ming-Qing Du; Christoph Mamot; Keith Pugh; Josh Caddy; Matthew A. Care; Jan Taylor; Reuben Tooze; ...
    Persistent Identifiers
    Publisher: American Society of Hematology

    Abstract Germinal Center (GCB) and activated (ABC) B-cell subtypes of DLBCL can be identified by Gene expression profiling (GEP). These subgroups are biologically distinct, harboring mutations in different pathways. Patients classified as ABC more often have mutations o...

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149,120 research outcomes, page 1 of 14,912