Filters
Clear AllFilters
Clear AllLoading
- publication . Article . Other literature type . 2018Open Access EnglishAuthors:Annik Imogen Gmel; Katrin Portele; Markus Neuditschko; Thomas Druml; Rudolf von Niederhäusern;Publisher: Public Library of Science (PLoS)
Linear description (LD) of conformation traits was introduced in horse breeding to minimise subjectivity in scoring. However, recent studies have shown that LD traits show essentially the same problems as traditionally scored traits, such as data converging around the m...
- publication . Article . Other literature type . 2015Open Access EnglishAuthors:Adam Labadorf; Schahram Akbarian; Zhiping Weng; Marcy E. MacDonald; Richard H. Myers; Jiang-Fan Chen; Tiffany C. Hadzi; Jeanne C. Latourelle; Joli Bregu; Valentina N. Lagomarsino; ...pmc: PMC4670106 ...Publisher: Public Library of ScienceProject: NIH | Epigenetic Markers in Hun... (5R01NS073947-02), NIH | GENETIC MODEL OF HUNTINGT... (5R01NS032765-07)
Huntington’s Disease (HD) is a devastating neurodegenerative disorder that is caused by an expanded CAG trinucleotide repeat in the Huntingtin (HTT) gene. Transcriptional dysregulation in the human HD brain has been documented but is incompletely understood. Here we pre...
- publication . Article . 2013Open Access EnglishAuthors:Terezinha Maria Castro Della Lucia; Juliana A. Morales; Danúbia G. Cardoso; Raul Narciso C. Guedes;pmc: PMC3694026pmid: 23840652Publisher: Public Library of Science
Submitted by JANAILTON DO CARMO SOARES (janailton.soares@ufv.br) on 2017-11-07T13:52:22Z No. of bitstreams: 1 journal.pone.0067283.PDF: 946117 bytes, checksum: 3c351628fb8ee8a6f11bb811af4be817 (MD5) Approved for entry into archive by Nathália Faria da Silva (nathaliafsi...
- publication . Article . 2014Open Access EnglishAuthors:David Anz; Doris Mayr; C. Hermans; Jutta Engel; Stefan Endres; Thomas Kirchner;pmc: PMC4218808pmid: 25365237Publisher: Ludwig-Maximilians-Universität München
Purpose: Tumor infiltrating CD4+CD25+FoxP3+ regulatory immune cells (Treg) have been associated with impaired antitumor immune response and unfavorable prognosis for patients affected by ovarian carcinoma, whereas CD8+T-cells have been found to positively influence surv...
- publication . Article . 2012Open AccessAuthors:Muthu Ramakrishnan; John E. Ladbury; Fernando A. Melo; Thomas R. Kosten; Frank M. Orson; Berma M. Kinsey;pmid: 22859949pmc: PMC3409241Project: NIH | Vaccines for Sustainable ... (5R01DA026859-04), NIH | Park2, A Parkinson Candid... (1Z01DA000454-01), NIH | Cocaine Pharmacotherapy T... (5P50DA018197-05), NIH | Development of Novel Vacc... (1R01DA030338-01), NIH | Development of a Human Hy... (5R01DA023979-03)
Background Despite progress in cocaine immunotherapy, the kinetic and thermodynamic properties of antibodies which bind to cocaine and its metabolites are not well understood. It is also not clear how the interactions between them differ in a complex matrix such as the ...
- publication . Article . 2012Open AccessAuthors:Young-Il Jeong; Sung-Hee Hong; Shin-Hyeong Cho; Won-Ja Lee; Sang Eun Lee;pmc: PMC3465325pmid: 23071588Publisher: Public Library of Science (PLoS)
BACKGROUND: Understanding the induction of immune regulatory cells upon helminth infection is important for understanding the control of autoimmunity and allergic inflammation in helminth infection. Babesia microti, an intraerythrocytic protozoan of the genus Babesia, i...
- publication . Article . Other literature type . 2013Open Access EnglishAuthors:Susan Hrisos; Richard Thomson;pmc: PMC3819291pmid: 24223230Publisher: Public Library of Science (PLoS)
Objective Encouraging patients to be more vigilant about their care challenges the traditional dynamics of patient-healthcare professional interactions. This study aimed to explore, from the perspectives of both patients and frontline healthcare staff, the potential con...
- publication . Article . 2012Open AccessAuthors:Jianfeng Cheng; Katherine P. Yates; Bradley E. Aouizerat; Andrew Joyce; Arun J. Sanyal;pmc: PMC3446974pmid: 23028489Publisher: Public Library of Science (PLoS)Project: NIH | Integration of functional... (5R01HG008140-02), NIH | Training Grant in Digesti... (5T32DK007150-31)
Vitamin E was recently shown to improve hepatic histology in a randomized controlled trial of pioglitazone or vitamin E for nonalcoholic steatohepatitis (PIVENS). The current study utilized samples collected in the PIVENS trial to identify: (1) baseline metabolomic prof...
- publication . Article . 2014Open Access EnglishAuthors:Rakesh C. Kukreja; Anindita Das; Mona Shalwala; Lei Xi; Shu-Guang Zhu; Fadi N. Salloum;pmc: PMC3899366pmid: 24466304Publisher: Public Library of ScienceProject: NIH | ROS, Inflammation, and Ca... (1R01HL118808-01), NIH | Cardioprotective Effects ... (2R01HL079424-05), NIH | Protection against Doxoru... (5R37HL051045-17)
BACKGROUND:It has been well documented that phosphodiesterase-5 inhibitor, sildenafil (SIL) protects against myocardial ischemia/reperfusion (I-R) injury. SIRT1 is part of the class III Sirtuin family of histone deacetylases that deacetylates proteins involved in cellul...
- publication . Article . 2015Open AccessAuthors:Luke Hogarth; Brendan Burkett; Mark R McKean;pmc: PMC4671542pmid: 26642320Publisher: Public Library of Science (PLoS)
This study determined the physical fitness, match-activity profiles and physiological responses of representative tag football players and examined the relationship between physical fitness and the match-activity profile. Microtechnology devices and heart rate (HR) ches...