Rare transitions between long-lived metastable states underlie a great variety of physical, chemical and biological processes. Our quantitative understanding of reactive mechanisms has been driven forward by the insights of transition state theory. In particular, the dy...

Repeated exposure to thin beauty ideals is part of the daily routine. Exposure to thin ideals via mass media plays an important role in the development and maintenance of eating disorders (EDs), low self-esteem, depressive or anxious feelings in young females. It is imp...

Charness and Dufwenberg (Am. Econ. Rev. 101(4):1211 1237 2011) have recently demonstrated that cheap talk communication raises efficiency in bilateral contracting situations with adverse selection. We replicate their main finding and extend their design to include compe...

Pneumocystis jirovecii is a fungus causing severe pneumonia in immuno-compromised patients. Progress in understanding its pathogenicity and epidemiology has been hampered by the lack of a long-term in vitro culture method. Obligate parasitism of this pathogen has been s...

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. Improvement of treatment efficacy and decreased side effects through tumor-targeted drug delivery would be desirable. By panning with a phage-displayed cyclic random peptide library we selected a...

International audience; Mantle-derived xenoliths hosted by melilitite lavas from In Teria (Ahaggar, SE Algeria) include garnet and spinel peridotites, pyroxenite and phlogopite megacrysts. The spinel and garnet peridotites record an early deformation event, which formed...

Features for speech emotion recognition are usually dominated by the spectral magnitude information while they ignore the use of the phase spectrum because of the difficulty of properly interpreting it. Motivated by recent successes of phase-based features for speech pr...

Aims/hypothesis Ageing can lead to reduced insulin sensitivity and loss of pancreatic beta cell function, predisposing individuals to the development of diabetes. The aim of this study was to assess the contribution of microRNAs (miRNAs) to age-associated beta cell dysf...

Two-celled puccinioid teliospores are widely distributed in the rust fungi and appear in several independent lineages of the Pucciniales. About 25 genera in 4 families have been described. Species with two-celled teliospores occurring on members of the Annonaceae are de...

Endogenous retroelements (EREs) are essential motors of evolution yet require careful control to prevent genomic catastrophes, notably during the vulnerable phases of epigenetic reprogramming that occur immediately after fertilization and in germ cells. Accordingly, a v...