textabstractAlthough there are no effective disease-modifying therapies for mitochondrial diseases, an increasing number of trials are being conducted in this rare disease group. The use of sensitive and valid endpoints is essential to test the effectiveness of potentia...

Objective: One of the risks of alcohol use is violent behavior. The aim of the current study was to explore the role of automatic cognitive associations between alcohol and power and between alcohol and aggression in alcohol-related aggression and to test the moderating...

Inspired by reliability issues in electric transmission networks, we use a probabilistic approach to study the occurrence of large failures in a stylized cascading failure model. In this model, lines have random capacities that initially meet the load demands imposed on...

Abstract Autologous fat transfer (AFT) is limited by post-operative volume loss due to ischemia-induced cell death in the fat graft. Previous studies have demonstrated that electrical stimulation (ES) promotes angiogenesis in a variety of tissues and cell types. In this...

Modern web application development frameworks provide web application developers with highlevel abstractions to improve their productivity. However, their support for static verification of applications is limited. Inconsistencies in an application are often not detecte...

This work uses experimental data to estimate the size of storage needed for an isolated off-grid household in two different regions (Austin, Texas, US, and Nunspeet, NL). In our study, an off-grid house is considered to be supplied with 100% renewable energy during the ...

The transition from low to high density 2D surface structures of copper porphyrins at a liquid/solid interface requires specific defects at which nearly all exchange of physisorbed molecules with those dissolved in the supernatant occurs.

Background Conditioning of physiological responses can be achieved by repeatedly pairing a previously neutral conditioned stimulus with the administration of a pharmacologically salient unconditioned stimulus. This type of conditioning has been effective for specific im...

Optic nerve assessment is important for many blinding diseases, with cup-to-disc ratio (CDR) assessments commonly used in both diagnosis and progression monitoring of glaucoma patients. Optic disc, cup, rim area and CDR measurements all show substantial variation betwee...

Background Since use of non-steroidal anti-inflammatory drugs (NSAIDs) during pregnancy is common, small increases in the risk of birth defects may have significant implications for public health. Results of human studies on the teratogenic risks of NSAIDs are inconsist...