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271,644 research outcomes, page 1 of 27,165
  • publication . Article . Other literature type . 2015
    Open Access English
    Authors:
    Adam Labadorf; Schahram Akbarian; Zhiping Weng; Marcy E. MacDonald; Richard H. Myers; Jiang-Fan Chen; Tiffany C. Hadzi; Jeanne C. Latourelle; Joli Bregu; Valentina N. Lagomarsino; ...
    Publisher: Public Library of Science
    Project: NIH | Epigenetic Markers in Hun... (5R01NS073947-02), NIH | GENETIC MODEL OF HUNTINGT... (5R01NS032765-07)

    Huntington’s Disease (HD) is a devastating neurodegenerative disorder that is caused by an expanded CAG trinucleotide repeat in the Huntingtin (HTT) gene. Transcriptional dysregulation in the human HD brain has been documented but is incompletely understood. Here we pre...

  • publication . Other literature type . Article . 2015
    Open Access
    Authors:
    Jianming Xu; Lan Liao; Yelin Wu; Yi Li; Yixiang Xu; Yan Xu; Jin Wang; Xian Wang; Li Qin; Xiaosong Wang; ...
    Publisher: Impact Journals, LLC
    Project: NIH | The Role of SRC-1 in Brea... (5R01CA112403-03)

    // Li Qin 1 , Yan Xu 2, 3 , Yixiang Xu 1, 4 , Gang Ma 1 , Lan Liao 1 , Yelin Wu 1, 5 , Yi Li 6 , Xian Wang 6 , Xiaosong Wang 6 , Jun Jiang 3 , Jin Wang 7 , Jianming Xu 1, 8 1 Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA 2 De...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Jonathan J. Shuster; Lorena Baccaglini; Douglas W. Theriaque; Zaeema Naveed;
    Publisher: John Wiley and Sons Inc.
    Project: NIH | UF Clinical and Translati... (3UL1TR000064-05S2), NIH | Growth Factors in Recurre... (7R03DE019687-02)

    Abstract Over 100 million Americans experience recurrent aphthous stomatitis (RAS) at some point in life. To develop targeted drugs for RAS treatment, it is critical to identify its etiology. We determined if serum insulin‐like growth factor 1 (IGF‐1) and related factor...

  • publication . Article . 2012
    Open Access
    Authors:
    Muthu Ramakrishnan; John E. Ladbury; Fernando A. Melo; Thomas R. Kosten; Frank M. Orson; Berma M. Kinsey;
    Project: NIH | Vaccines for Sustainable ... (5R01DA026859-04), NIH | Park2, A Parkinson Candid... (1Z01DA000454-01), NIH | Cocaine Pharmacotherapy T... (5P50DA018197-05), NIH | Development of Novel Vacc... (1R01DA030338-01), NIH | Development of a Human Hy... (5R01DA023979-03)

    Background Despite progress in cocaine immunotherapy, the kinetic and thermodynamic properties of antibodies which bind to cocaine and its metabolites are not well understood. It is also not clear how the interactions between them differ in a complex matrix such as the ...

  • publication . Other literature type . Article . 2014
    Open Access
    Authors:
    Howard H. Chang; W. Dana Flanders; Katherine Gass; Mitch Klein; Matthew J. Strickland;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | Relationships between air... (5K01ES019877-02)

    Background: Identifying and characterizing how mixtures of exposures are associated with health endpoints is challenging. We demonstrate how classification and regression trees can be used to generate hypotheses regarding joint effects from exposure mixtures. Methods: W...

  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Yolanda Evans; Nikita Midamba; Megan A. Moreno; Ellen Selkie; Adrienne Ton;
    Project: NIH | Psychiatry Primary Care N... (2T32MH020021-16)

    Background Electronic harassment affects 20–40% of adolescents and has been associated with significant negative outcomes including physical (ex. headache, abdominal pain), psychological (ex. depression, anxiety), and psychosocial (ex. school avoidance) problems. Eviden...

  • publication . Preprint . Other literature type . 2019
    Open Access English
    Authors:
    Nelson C. Coelho; Aaron C. Wacholder; Allyson F. O'Donnell; Brian Hsu; Aoife McLysaght; Carlos J. Camacho; Anne-Ruxandra Carvunis; Nikolaos Vakirlis; Omer Acar; Trey Ideker; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: EC | DOSE (309834), NIH | A Systems Approach to Map... (5R01ES014811-08), NIH | Core_Training (2P41GM103504-06), NIH | Deciphering the mechanism... (5R00GM108865-04), NIH | Investigating mechanisms ... (1F32GM129929-01)

    <jats:title>Summary</jats:title><jats:p>Recent evidence demonstrates that novel protein-coding genes can arise<jats:italic>de novo</jats:italic>from intergenic loci. This evolutionary innovation is thought to be facilitated by the pervasive translation of intergenic tra...

  • publication . Article . Other literature type . 2020
    Open Access
    Authors:
    Brittany A. Wheatley; Wenxia Song; Zhou Shu; Zhou Shu; Ivan Rey-Suarez; Ivan Rey-Suarez; Peter K. Koo; Hari Shroff; Arpita Upadhyaya; Simon G. J. Mochrie; ...
    Publisher: Springer Science and Business Media LLC
    Project: NSF | Collaborative Research: F... (1806903), NIH | Nanotopographic modulatio... (1R21AI122205-01A1), NSF | Collaborative Research: P... (1522467)

    Regulation of membrane receptor mobility tunes cellular response to external signals, such as in binding of B cell receptors (BCR) to antigen, which initiates signaling. However, whether BCR signaling is regulated by BCR mobility, and what factors mediate this regulatio...

  • publication . Article . 2015
    Open Access English
    Authors:
    Madhav Goyal; David A. Seminowicz; Michael L. Keaser; Shariq A. Khan; Vani A. Mathur; Catherine S. Hubbard;
    Publisher: The Authors. Published by Elsevier Inc.
    Project: NIH | MRI outcomes of mindfulne... (5R01AT007176-05), NIH | Interdisciplinary Trainin... (5T32NS070201-08), NIH | Institute for Clinical an... (1KL2RR025006-01)

    Little is known about the effect of migraine on neural cognitive networks. However, cognitive dysfunction is increasingly being recognized as a comorbidity of chronic pain. Pain appears to affect cognitive ability and the function of cognitive networks over time, and de...

  • publication . Preprint . Article . Other literature type . 2012
    Open Access English
    Authors:
    Salvatore Torquato; Yang Jiao;
    Project: NIH | Education and Training (5U54CA143803-05)

    Complex tumor-host interactions can significantly affect the growth dynamics and morphologies of progressing neoplasms. The growth of a confined solid tumor induces mechanical pressure and deformation of the surrounding microenvironment, which in turn influences tumor g...

271,644 research outcomes, page 1 of 27,165