Motivation: Combinatorial biomarkers are considered more specific and sensitive than single markers in medical diagnostics and prediction, yet even detection of such these combinatorial biomarkers requires deep computational analysis. The principles of analytic combinat...

Motivation: In literature, several transformations exists to obtain a new cumulative distribution function (cdf) using other(s) well-known cdf(s). Results: In this note we find applications of some new cumulative distribution function transformations to construct a fami...

The scutes located on the carapace of the red-eared slider Trachemys scripta elegans (Wied-Neuwied, 1839) have been modeled. Bioinformatics modeling of carapace’s scutes were carried out by utilizing the Voronoi decomposition and Delaunay triangulation method. These two...

DNA Cryptography can be defined as a hiding data in terms of DNA Sequence. In this paper we propose a new DNA Encryption Technique where three different types of ordering is use to make binary data into cipher text. The main stages of this encryption technique are: Key ...

Summary: A simple-to-use Java-based software package CelNetAnalyzer was developed. CelNetAnalyzer is managed through a graphical user interface and it returns a comprehensive list of the topological indices including compositional complexity, degree and neighbourhood, c...

A brief review is given of recent advances in the taxonomic study of organisms and current views on biological evolution and the origin of life. A discussion is presented on how the treelike and net components contribute to the topology of phylogenetic constructs, with ...

Motivation: Massive parallel phylogenetic analyses allow to reconstruct phylogenetic trees for every gene in genome, typically using the set of potential homologues detected via BLAST or analogue. However, if the amount of hits is too high, the dataset should be reduced...

Motivation: In early stage of therapeutics, several structure and ligand-based in-silico approaches have aided the modern drug discovery and design. However, such techniques are limited by availability of resolved 3D structures of targets and ligands. At the same time t...

The study of special features of a new molecular DNA structure synthesis based on the fact that monomers transpositions can occur in the backbone of polymer chains according to the mathematical law known as a Fibonacci numerical series and «the Golden ratio» was perform...

Motivation: Meiosis — a two-stage process of sex cell division — is served by several hundreds of proteins. A part of them went to eukaryotes from prokaryotes, others appeared in first eukaryotes, and some proteins appeared de novo in multicellular eukaryotes. We compar...