A brief review is given of recent advances in the taxonomic study of organisms and current views on biological evolution and the origin of life. A discussion is presented on how the treelike and net components contribute to the topology of phylogenetic constructs, with ...

Motivation: In literature, several transformations exists to obtain a new cumulative distribution function (cdf) using other(s) well-known cdf(s). Results: In this note we find applications of some new cumulative distribution function transformations to construct a fami...

The scutes located on the carapace of the red-eared slider Trachemys scripta elegans (Wied-Neuwied, 1839) have been modeled. Bioinformatics modeling of carapace’s scutes were carried out by utilizing the Voronoi decomposition and Delaunay triangulation method. These two...

Currently existing methods and parameters are inadequate for representative and quanititative assessment of cytotoxic activity of chemical compounds. Recently, we have introduced a concept of cytotoxic power which provides an effective way to a reasonable estimation and...

The most general model of a pairwise global alignment with the possibility of aligning long sequences is considered. The model features are alignment of sequences in different alphabets including nucleotides and amino acids, alternative alignments with the same score, p...

Motivation: The human microbiome plays an important role in human health and disease. The composition of the human microbiome is influenced by multiple factors and understanding these factors is critical to elucidate the role of the microbiome in health and disease and ...

Motivation: The browser-based visualization of Hi-C contact maps alongside complementary data tracks is a computationally challenging task and requires an efficient software implementation to run on small clients. Few software packages have yet been shared with the comm...

Summary: A simple-to-use Java-based software package CelNetAnalyzer was developed. CelNetAnalyzer is managed through a graphical user interface and it returns a comprehensive list of the topological indices including compositional complexity, degree and neighbourhood, c...

The structure of noncoding RNAs largely determines their functions. With the rapid growth of experimental data on the RNA secondary structures, the task of predicting its spatial structure becomes the most urgent task of RNA bioinformatics. The ability to predict tertia...

Motivation: Massive parallel phylogenetic analyses allow to reconstruct phylogenetic trees for every gene in genome, typically using a set of potential homologues detected by similarity search against reference databases via BLAST or BLAST-like algorithms. However, give...