Colorectal cancer (CRC) is an aggressive human malignancy with a complex genomic landscape harboring KRAS mutations. In 40%–60% of patients with CRC, constantly active KRAS proteins affect the prognosis, surgical strategy, and clinical benefit from therapy with anti-epi...

This paper is concerned with the development of a model for knowledge of consequences which can support provident reasoning design. The work is focused on part design synthesis decision making so as to support individual designers engaged in life-cycle design exploratio...

The objective of the present study was to develop a scale that is appropriate for use internationally to measure affective, behavioral, and cognitive dimensions of student engagement. Psychometric properties of this scale were examined with data of 3,420 students (7th, ...

This article is only intended to serve as an outline, a brief explanation of the salient principles and the most significant changes introduced to the Law of Succession. It is hoped that it will serve to tickle the reader into a more profound study and examination of th...

The advent of war in any country heralds a total upheaval in the social and demographic characteristics of the community through "war casualties" and changes in the reproductive patterns in the population. Demographic changes may also be evident in neighbouring countrie...

It is with pleasure but also with great concern that I write this editorial for an issue that has a major focus on issues of relevance and importance to primary health care and therefore healthcare and health service provision in Malta. Our guest editorial by Dr Jürgen ...

Brain illnesses are among the most important causes of death and disability worldwide. While 0.4 million people die from breast cancer every year, 1 million commit suicide. Add death due to drugs of abuse, Alzheimer’s, Parkinson’s and other neurodegenerative disorders, ...

A healthy female infant was found to have two umbilical arteries and two umbilical veins at the cut surface of the cord at birth. Detailed inspection of the cord showed the second vein to represent a short segment vestigial vessel that, moreover, was not associated with...