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- publication . 2018Open AccessAuthors:Galilee, Meytal; Alian, Akram;Persistent Identifiers
doi: 10.1101/301721
Publisher: bioRxivProject: EC | iNEXT (653706)ABSTRACTNew anti-AIDS treatments must be continually developed in order to overcome resistance mutations including those emerging in the newest therapeutic target, the viral integrase (IN). Multimerization of IN is functionally imperative and provides a forthcoming ther...
Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2020Open Access EnglishAuthors:Guillaume Tetreau; Anne-Sophie Banneville; Elena A. Andreeva; Aaron S. Brewster; Mark S. Hunter; Raymond G. Sierra; Jean-Marie Teulon; Iris D. Young; Niamh Burke; Tilman A. Grünewald; ...Persistent IdentifiersPublisher: HAL CCSDCountries: France, United StatesProject: NIH | A Synchroton Radiation St... (8P41GM103393-33), ANR | CBH-EUR-GS (ANR-17-EURE-0003), NIH | Pacific Southwest Regiona... (1U01CK000516-01), NIH | Highly Improved Bacterial... (1U01AI054778-01), NIH | DIALS: New Computational ... (5R01GM117126-02), ANR | X-in-vivo (ANR-17-CE11-0018), NIH | A SYNCHROTRON RADIATION B... (5P41RR001209-14), NIH | Molecular Improvement of ... (5R01AI045817-04), ANR | DynOCP (ANR-18-CE11-0005)
Cyt1Aa is the one of four crystalline protoxins produced by mosquitocidal bacterium Bacillus thuringiensis israelensis (Bti) that has been shown to delay the evolution of insect resistance in the field. Limiting our understanding of Bti efficacy and the path to improved...
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You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2019Open AccessAuthors:Hõrak, Peeter; Valge, Markus; Fischer, Krista; Mägi, Reedik; Kaart, Tanel;Persistent IdentifiersPublisher: WileyProject: EC | ADOPT BBMRI-ERIC (676550), EC | WIDENLIFE (692065), EC | ePerMed (692145), EC | CORBEL (654248)
Abstract According to the life‐history theory, rates of sexual maturation have coevolved with mortality rates so that individuals who mature faster tend to die younger. We used two data sets, providing different markers for the speed of pubertal development to test whet...
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You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2015Authors:Niels Krogsgaard-Larsen; Morten Storgaard; Charlotte Møller; Charles S. Demmer; J.B. Hansen; Liwei Han; Rune N. Monrad; Birgitte Nielsen; Daniel Tapken; Darryl S. Pickering; ...Persistent IdentifiersPublisher: American Chemical Society (ACS)Project: EC | BIOSTRUCT-X (283570)
Herein we describe the first structure–activity relationship study of the broad-range iGluR antagonist (2S,3R)-3-(3-carboxyphenyl)pyrrolidine-2-carboxylic acid (1) by exploring the pharmacological effect of substituents in the 4, 4′, or 5′ positions and the bioisosteric...
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You have already added works in your ORCID record related to the merged research outcome. - publication . Article . Other literature type . 2020Open Access EnglishAuthors:Odermatt, Nina,; Lelli, Moreno; Herrmann, Torsten; Abriata, Luciano,; Japaridze, Aleksandre; Voilquin, Hubert; Singh, Rajkumar; Piton, Jérémie; Emsley, Lyndon; Dietler, Giovanni; ...Persistent IdentifiersPublisher: HAL CCSDCountries: Switzerland, FranceProject: EC | iNEXT (653706)
Abstract In bacteria, nucleoid associated proteins (NAPs) take part in active chromosome organization by supercoil management, three-dimensional DNA looping and direct transcriptional control. Mycobacterial integration host factor (mIHF, rv1388) is a NAP restricted to A...
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You have already added works in your ORCID record related to the merged research outcome. - publication . Article . Other literature type . 2018Open AccessAuthors:Weinhäupl, Katharina; Brennich, Martha; Kazmaier, Uli; Lelièvre, Joël; Ballell, Lluis; Goldberg, Alfred; Schanda, Paul; Fraga, Hugo;Persistent IdentifiersCountry: France
Mycobacterium tuberculosis can remain dormant in the host, an ability that explains the failure of many current tuberculosis treatments. Recently, the natural products cyclomarin, ecumicin, and lassomycin have been shown to efficiently kill Mycobacterium tuberculosis pe...
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You have already added works in your ORCID record related to the merged research outcome. - publication . Doctoral thesis . 2020Open Access EnglishAuthors:Denis, Maxime Jacques Gil;Country: ItalyProject: EC | AEGIS (675555), EC | iNEXT (653706)
- publication . Article . 2016Open AccessAuthors:Haikarainen, Teemu; Waaler, Jo; Ignatev, Alexander; Nkizinkiko, Yves; Venkannagari, Harikanth; Obaji, Ezeogo; Krauss, Stefan; Lehtiö, Lari;Persistent IdentifiersPublisher: Elsevier BVProject: EC | BIOSTRUCT-X (283570), AKA | Characterization of poly(... (266922)
AbstractTankyrases 1 and 2, the specialized members of the ARTD protein family, are druggable biotargets whose inhibition may have therapeutic potential against cancer, metabolic disease, fibrotic disease, fibrotic wound healing and HSV viral infections. We have previou...
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You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2019Open AccessAuthors:Linda Cerofolini; Stefano Giuntini; Letizia Barbieri; Matteo Pennestri; Anna Codina; Marco Fragai; Lucia Banci; Enrico Luchinat; Enrico Ravera;Persistent IdentifiersCountry: ItalyProject: EC | West-Life (675858), EC | INSTRUCT-ULTRA (731005), EC | iNEXT (653706)
FlowNMR has the aim of continuously monitoring processes that occur in conditions that are not compatible with being carried out within a closed tube. However, it is sample intensive and not suitable for samples, such as proteins or living cells, that are often availabl...
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You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2017Open AccessAuthors:Franke, D.; Petoukhov, M. V.; Konarev, P. V.; Panjkovich, A.; Tuukkanen, A.; Mertens, H. D. T.; Kikhney, A. G.; Hajizadeh, N. R.; Franklin, J. M.; Jeffries, C. M.; ...Persistent IdentifiersPublisher: International Union of Crystallography (IUCr)Project: EC | iNEXT (653706), EC | IDPBYNMR (264257), EC | BIOSTRUCT-X (283570)
ATSAS is a comprehensive software suite for the analysis of small-angle scattering data from dilute solutions of biological macromolecules or nanoparticles. It contains applications for primary data processing and assessment, ab initio bead modelling, and model validati...
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You have already added works in your ORCID record related to the merged research outcome.