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- publication . Article . 2009Open AccessAuthors:Papadopoulos, G. L.; Alexiou, P.; Maragkakis, M.; Reczko, M.; Hatzigeorgiou, A. G.;Persistent IdentifiersPublisher: Oxford University Press (OUP)
Summary: DIANA-mirPath is a web-based computational tool developed to identify molecular pathways potentially altered by the expression of single or multiple microRNAs. The software performs an enrichment analysis of multiple microRNA target genes comparing each set of ...
Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2019Open Access EnglishAuthors:Norman E. Davey; M. Madan Babu; Martin Blackledge; Alan Bridge; Salvador Capella-Gutierrez; Zsuzsanna Dosztanyi; Rachel Drysdale; Richard J. Edwards; Arne Elofsson; Isabella C. Felli; ...Publisher: F1000 Research Ltd
Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are now recognised as major determinants in cellular regulation. This white paper presents a roadmap for future e-infrastructure developments in the field of IDP research within the ELI...
- publication . Article . 2009Open Access EnglishAuthors:Panagiotis Alexiou; Thanasis Vergoulis; Martin Gleditzsch; George Prekas; Theodore Dalamagas; Molly Megraw; Ivo Grosse; Timos Sellis; Artemis G. Hatzigeorgiou;Persistent IdentifiersPublisher: Oxford University Press
MicroRNAs are small, non-protein coding RNA molecules known to regulate the expression of genes by binding to the 3 0 UTR region of mRNAs. MicroRNAs are produced from longer transcripts which can code for more than one mature miRNAs. miRGen 2.0 is a database that aims t...
Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2016Closed AccessAuthors:Vasiliki D. Kostiou; Margarita C. Theodoropoulou; Stavros J. Hamodrakas;Persistent IdentifiersPublisher: Elsevier BV
Heterotrimeric G-proteins form a major protein family, which participates in signal transduction. They are composed of three subunits, Gα, Gβ and Gγ. The Gα subunit is further divided in four distinct families Gs, Gi/o, Gq/11 and G12/13. The goal of this work was to det...
Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . Other literature type . 2015Open Access EnglishAuthors:Huber, Wolfgang; Carey, Vincent J; Gentleman, Robert; Anders, Simon; Carlson, Marc; Carvalho, Benilton S; Bravo, Hector Corrada; Davis, Sean; Gatto, Laurent; Girke, Thomas; ...Persistent IdentifiersCountry: Belgium
Bioconductor is an open-source, open-development software project for the analysis and comprehension of high-throughput data in genomics and molecular biology. The project aims to enable interdisciplinary research, collaboration and rapid development of scientific softw...
Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. PRED-TAT is a tool that takes a protein sequence as input and discriminating Sec from Tat signal peptides and predicting their cleavage sites.
- publication . Article . 2015Open AccessAuthors:Duarte, Afonso M S; Psomopoulos, Fotis E; Blanchet, Christophe; Bonvin, Alexandre M J J; Corpas, Manuel; Franc, Alain; Jimenez, Rafael C; de Lucas, Jesus M; Nyrönen, Tommi; Sipos, Gergely; ...Persistent IdentifiersPublisher: Frontiers MediaCountries: France, France, France, France, France, NetherlandsProject: WT , EC | BIOMEDBRIDGES (284209), EC | WENMR (261572), FCT | EXPL/BBB-BEP/1356/2013 (EXPL/BBB-BEP/1356/2013), EC | EGI-INSPIRE (261323), FCT | SFRH/BPD/78075/2011 (SFRH/BPD/78075/2011), AKA | ELIXIR - Data for Life Eu... (273655)
With the increasingly rapid growth of data in life sciences we are witnessing a major transition in the way research is conducted, from hypothesis-driven studies to data-driven simulations of whole systems. Such approaches necessitate the use of large-scale computationa...
Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2019Open AccessAuthors:Davey, Norman E.; Babu, M. Madan; Blackledge, Martin; Bridge, Alan; Capella-Gutierrez, Salvador; Dosztanyi, Zsuzsanna; Drysdale, Rachel; Edwards, Richard J.; Elofsson, Arne; Felli, Isabella C.; ...Persistent IdentifiersCountries: Belgium, United Kingdom, United Kingdom, Cyprus, Netherlands, SpainProject: UKRI | Bioinformatics Resources ... (BB/P024092/1), NIH | UniProt supporting an int... (3U24HG007822-05S1), WT | Protein Data Bank in Euro... (104948), EC | IDPfun (778247)
Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are now recognised as major determinants in cellular regulation. This white paper presents a roadmap for future e-infrastructure developments in the field of IDP research within the ELI...
Add to ORCID Please grant OpenAIRE to access and update your ORCID works.This research outcome is the result of merged research outcomes in OpenAIRE.
You have already added works in your ORCID record related to the merged research outcome. - publication . Article . 2021Open AccessAuthors:Maria Vasilarou; Nikolaos Alachiotis; Joanna Garefalaki; Apostolos Beloukas; Pavlos Pavlidis;Persistent IdentifiersCountry: Netherlands
Full-genome-sequence computational analyses of the SARS-coronavirus (CoV)-2 genomes allow us to understand the evolutionary events and adaptability mechanisms. We used population genetics analyses on human SARS-CoV-2 genomes available on 2 April 2020 to infer the mutati...
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You have already added works in your ORCID record related to the merged research outcome. HMM-TM is a tool that takes a protein sequence as input and predicts the transmembrane regions of alpha-helical