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82,059 research outcomes, page 1 of 8,206
  • publication . Preprint . 2017
    Open Access
    Authors:
    Romain Libbrecht; Daniel J. C. Kronauer; Peter R. Oxley;
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | Studying the molecular me... (1DP2GM105454-01), EC | ANTEPIGENETICS (327992)

    <jats:title>Abstract</jats:title><jats:p>Division of labor between reproductive queens and non-reproductive workers that perform brood care is the hallmark of insect societies. However, the molecular basis of this fundamental dichotomy remains poorly understood, in part...

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  • publication . Preprint . 2017
    Open Access
    Authors:
    David C. Godlove; Jeffrey D. Schall; Amirsaman Sajad;
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | NEURAL CONTROL OF VOLUNTA... (5R01MH055806-05), NIH | CORE--ILLUSTRATION AND PH... (5P30EY008126-08)

    <jats:p>Cortical circuit mechanisms in medial frontal cortex enabling executive control are unknown. Hence, in monkeys performing a saccade countermanding task to earn larger or smaller fluid rewards, we sampled spiking and synaptic activity simultaneously across all la...

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  • publication . Other literature type . Article . Preprint . 2018
    Open Access
    Authors:
    Frederic Bard; Joanne Chia; Felicia P. L. Tay;
    Publisher: Public Library of Science (PLoS)

    The enzymes GALNTs add GalNAc sugar to Ser and Thr residues, forming the Tn glycan. GALNTs are activated by trafficking from Golgi to ER, a process driven by the Src kinase and negatively regulated by ERK8. This GALNTs activation (aka GALA) pathway induces high Tn level...

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  • publication . Other literature type . Preprint . 2019
    Open Access
    Authors:
    Bittleston, Leonora S.; Gralka, Matti; Leventhal, Gabriel E.; Mizrahi, Itzhak; Cordero, Otto X.;
    Publisher: bioRxiv
    Project: EC | RuMicroPlas (640384)

    <jats:title>Abstract</jats:title><jats:p>Niche construction through interspecific interactions can condition future community states on past ones. However, the extent to which such history dependency can steer communities towards functionally different states remains a ...

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  • publication . Preprint . Article . Other literature type . 2019
    Open Access
    Authors:
    Deepa Agashe; Imroze Khan; Imroze Khan; Arun Prakash;
    Publisher: Cold Spring Harbor Laboratory

    In many insects, individuals primed with low doses of pathogens early in life have higher survival after exposure to the same pathogen later in life. Yet, our understanding of the evolutionary and ecological history of priming of immune response in natural insect popula...

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  • publication . Preprint . Article . Other literature type . 2019
    Open Access English
    Authors:
    William Allan King; Mark Ungrin; Ina Dobrinski; Taylor Goldsmith; D.A.F. Villagómez; D.A.F. Villagómez; Kyle Burrell; Franklin D. West; Derek Toms; Rkia Dardari;
    Publisher: Cold Spring Harbor Laboratory

    <jats:title>Abstract</jats:title><jats:p>Induced pluripotent stem cells (iPSCs) are an attractive cell source for regenerative medicine and the development of therapies, as they can proliferate indefinitely under defined conditions and differentiate into any cell type i...

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  • publication . Preprint . 2018
    Open Access English
    Authors:
    Frederick S. Barrett; Matthew H. Panicker; Samuel R. Krimmel; David A. Seminowicz; Brian N. Mathur; Michael G. White;
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | Ethanol Remodeling of Str... (5K22AA021414-03), NIH | Mechanism of protection a... (5F31AA024683-02), NIH | Striatal Microcircuit Dyn... (5R01AA024845-02), NIH | Measurement of persisting... (1R03DA042336-01), NIH | MRI outcomes of mindfulne... (5R01AT007176-05), NIH | Training Program in Neuro... (5T32NS063391-14)

    <jats:title>Abstract</jats:title><jats:p>The claustrum is among the most highly connected structures in the mammalian brain. However, the function of the claustrum is unknown, which is due to its peculiar anatomical arrangement. Here, we use resting state and task funct...

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  • publication . Preprint . 2019
    Open Access
    Authors:
    Soojin V. Yi; Noriyoshi Usui; Noriyoshi Usui; Isabel Mendizabal; Genevieve Konopka; Todd M. Preuss; Iksoo Huh; Iksoo Huh; Hyeonsoo Jeong; Carol A. Tamminga; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | A National Chimpanzee Bra... (1R24NS092988-01), NIH | Support of Yerkes Nationa... (5P51OD011132-53)

    <jats:title>Abstract</jats:title><jats:p>The importance of cell-type specific epigenetic variation of non-coding regions in neuropsychiatric disorders is increasingly appreciated, yet data from disease brains are conspicuously lacking. We generated cell-type specific wh...

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  • publication . Preprint . 2015
    Open Access
    Authors:
    John D. Chodera; Joel Tellinghuisen; S.E. Boyce;
    Publisher: Cold Spring Harbor Laboratory

    <jats:p>Isothermal titration calorimetry (ITC) can yield precise (±3%) estimates of the thermodynamic parameters describing biomolecular association (affinity, enthalpy, and entropy), making it an indispensable tool for biochemistry and drug discovery. Surprisingly, int...

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  • publication . Preprint . Article . Other literature type . 2019
    Open Access
    Authors:
    Hao Lu; Priyanka Anujan; Colin D. Bingle; Yan Ling Chong; Feng Zhou; Sudipto Roy; Yiliu Zhang;
    Publisher: Cold Spring Harbor Laboratory

    <jats:title>ABSTRACT</jats:title><jats:p>Motile cilia on multiciliated cells (MCCs) function in fluid clearance over epithelia. Studies with <jats:italic>Xenopus</jats:italic> embryos and patients with the congenital respiratory disorder reduced generation of multiple m...

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82,059 research outcomes, page 1 of 8,206