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2,163,882 research outcomes, page 1 of 216,389
  • publication . Article . 1985
    Route- and dose-dependent pharmacokinetics of hexobarbitone in the rat
    Open Access English
    Authors:
    M. Van Der Graaff; N. P. E. Vermeulen; Douwe D. Breimer;
    Persistent Identifiers

    doi: 10.1111/j.2042-7158.1985.tb03065.x

    handle: 1871.1/133c32f6-5118-4ef4-885e-22fa6b4ff7fd

    Country: Netherlands

    Abstract The metabolic clearance (CL) and half-life of racemic hexobarbitone and sleeping time were studied in rats following intra-arterial (i.a.), intraperitoneal (i.p.) and oral (p.o.) administration, at dose levels of 25 and 100 mg kg−1 of its sodium salt. CLp.o. wa...

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  • publication . Article . 2014
    Which activity monitor to use? Validity, reproducibility and user friendliness of three activity monitors
    Open Access
    Authors:
    Brenda A J Berendsen; Marike R C Hendriks; Kenneth Meijer; Guy Plasqui; Nicolaas C. Schaper; Hans H.C.M. Savelberg;
    Persistent Identifiers

    doi: 10.1186/1471-2458-14-749

    pmc: PMC4133601

    pmid: 25059233

    Country: Netherlands

    BACKGROUND: Health is associated with amount of daily physical activity. Recently, the identification of sedentary time as an independent factor, has gained interest. A valid and easy to use activity monitor is needed to objectively investigate the relationship between ...

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  • publication . Article . 2002
    Detection of unknown primary tumours and distant metastases in patients with cervical metastases: value of FDG-PET versus conventional modalities
    Restricted
    Authors:
    Gerreke Regelink; Jolijn Brouwer; Remco de Bree; Jan Pruim; Bernard F. A. M. van der Laan; Willem Vaalburg; Otto S. Hoekstra; Emile F.I. Comans; Arjan Vissink; C. René Leemans; ...
    Persistent Identifiers

    doi: 10.1007/s00259-002-0819-0

    handle: 11370/9c31d89b-4d25-437d-ad2f-688655e02f60

    Publisher: Springer Science and Business Media LLC
    Country: Netherlands

    In 1%-2% of head and neck oncology patients, the only symptom of a malignancy is a positive cervical node. The aim of this study was to compare the value of positron emission tomography using fluorine-18 fluoro-2-deoxy-D-glucose (FDG-PET) and conventional diagnostic mod...

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  • publication . Article . 2006
    Hemodynamic effects of angiotensin II and the influence of angiotensin receptor antagonists in pithed rabbits
    Restricted English
    Authors:
    J. Zhang; Martin Pfaffendorf; P. A. Van Zwieten;
    Persistent Identifiers

    doi: 10.1097/00005344-199505000-00007

    Country: Netherlands

    We investigated the cardiovascular effects of angiotensin II (AII) and the influences of four angiotensin receptor antagonists: losartan, PD123177, BIBS 39, and BIBS 222 in the pithed rabbit preparation. AII (0.03-10 nmol/kg) elicited a dose-dependent increase in blood ...

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  • publication . Article . 2014
    The Role of the Mean State of Arctic Sea Ice on Near-Surface Temperature Trends
    Open Access English
    Authors:
    E. C. van der Linden; Richard Bintanja; Wilco Hazeleger; Caroline A. Katsman;
    Persistent Identifiers

    doi: 10.1175/jcli-d-12-00617.1

    Country: Netherlands

    Abstract Century-scale global near-surface temperature trends in response to rising greenhouse gas concentrations in climate models vary by almost a factor of 2, with greatest intermodel spread in the Arctic region where sea ice is a key climate component. Three factors...

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  • publication . Article . 2012
    Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase
    Open Access English
    Authors:
    Buganim, Yosef; Faddah, Dina A.; Cheng, Albert W.; Itskovich, Elena; Markoulaki, Styliani; Ganz, Kibibi; Klemm, Sandy L.; van Oudenaarden, Alexander; Jaenisch, Rudolf;
    Persistent Identifiers

    doi: 10.1016/j.cell.2012.08.023

    handle: 20.500.11755/0a762101-98ff-4932-aa21-3b9d97b380f4

    Publisher: Elsevier Inc.
    Country: Netherlands
    Project: NIH | Stochastic gene expressio... (5DP1OD003936-02), NIH | In Vitro Reprogramming of... (5R37HD045022-13), NIH | Utilizing single cell app... (1F32GM099153-01A1), NIH | Organization and Infrastr... (5U54CA143874-04), NIH | GENOMIC IMPRINTING AND TH... (5R37CA084198-09)

    SummaryDuring cellular reprogramming, only a small fraction of cells become induced pluripotent stem cells (iPSCs). Previous analyses of gene expression during reprogramming were based on populations of cells, impeding single-cell level identification of reprogramming e...

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  • publication . Article . 2012
    Novel diglycolamide functionalized calix[4]arenes for actinide extraction and supported liquid membrane studies: Part II. Role of substituents in the pendent arms and mass transfer modeling I
    Restricted English
    Authors:
    Seraj A. Ansari; Prasanta K. Mohapatra; Mudassir Iqbal; Pankaj Kandwal; Jurriaan Huskens; Willem Verboom;
    Persistent Identifiers

    doi: 10.1016/j.memsci.2012.11.081

    Country: Netherlands

    Several calix[4]arene-functionalized diglycolamide (C4DGA) ligands were evaluated for the extraction as well as supported liquid membrane (SLM) transport of actinides and fission product elements from nitric acid feed solutions. The extraction efficiency of the C4DGA li...

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  • publication . Part of book or chapter of book . 2014
    Van lezen naar schrijven
    Restricted Dutch; Flemish
    Authors:
    Jansma, Marijke; Aalbers, Friso S.; Poolman, Bert; Hoekstra, Wiel; van Maris, Ton; Poolman, Bert; Pronk, Jack; Buiter, Rob;
    Publisher: Drukkerij Tesink, Zutphen
    Country: Netherlands
  • publication . Article . 2015
    Enhanced catalytic performance of zeolite ZSM-5 for conversion of methanol to dimethyl ether by combining alkaline treatment and partial activation
    Closed Access
    Authors:
    Wei, Ying; de Jongh, Petra E.; Bonati, Matteo L. M.; Law, David J.; Sunley, Glenn J.; de Jong, Krijn P.; Inorganic Chemistry and Catalysis; Sub Inorganic Chemistry and Catalysis;
    Persistent Identifiers

    doi: 10.1016/j.apcata.2014.12.027

    handle: 1874/330187

    Publisher: Elsevier BV
    Country: Netherlands

    Zeolite ZSM-5 (MFI) due to its excellent hydrothermal stability and high catalytic activity for methanol dehydration to dimethyl ether (MID) has been considered for use in combination with a methanol synthesis catalyst, such as Cu/ZnO/Al2O3, in the conversion of syngas ...

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  • publication . Article . Other literature type . 2018
    Characterization of male breast cancer: results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program
    Open Access English
    Authors:
    Cardoso, F; Bartlett, J M S; Slaets, L; van Deurzen, C H M; van Leeuwen-Stok, E; Porter, P; Linderholm, B; Hedenfalk, I; Schröder, C; Martens, J; ...
    Persistent Identifiers

    doi: 10.1093/annonc/mdx651

    handle: 1887/79616 , 11370/ae00c5d2-7630-4ecb-a9ca-a6f25d2c406f

    pmc: PMC5834077

    pmid: 29092024

    Country: Netherlands

    Background: Male breast cancer (BC) is rare, managed by extrapolation from female BC. The International Male BC Program aims to better characterize and manage this disease. We report the results of part I, a retrospective joint analysis of cases diagnosed during a 20-ye...

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2,163,882 research outcomes, page 1 of 216,389