Filters (2)
Download Results
72,404 research outcomes, page 1 of 7,241
  • publication . Article . 2015
    Open Access English
    Authors:
    PJ Hyde; Richard M. Hall; John Fisher;
    Persistent Identifiers
    Publisher: Wiley
    Project: WT | Engineering Solutions for... (088908), NIH | Wear Analysis of Interver... (5R01AR052653-03), RCUK | DTA - University of Leeds (EP/P504988/1)

    Abstract The effect of kinematics, loading and centre of rotation on the wear of an unconstrained total disc replacement have been investigated using the ISO 18192‐1 standard test as a baseline. Mean volumetric wear rate and surface morphological effects were reported. ...

    Add to ORCID
  • publication . Preprint . 2020
    Open Access English
    Authors:
    Jolicoeur, Sheean; Maartens, Roy; De Weerd, Eline M.; Umeh, Obinna; Clarkson, Chris; Camera, Stefano;
    Project: RCUK | Cosmology and Astrophysic... (ST/N000668/1), RCUK | Astronomy Research at Que... (ST/P000592/1)

    We investigate the detectability of leading-order relativistic effects in the bispectrum of future 21cm intensity mapping surveys. The relativistic signal arises from Doppler and other line-of-sight effects in redshift space. In the power spectrum of a single tracer, th...

  • publication . Preprint . 2020
    Open Access English
    Authors:
    Fabbian, G.; Carron, J.; Lewis, A.; Lembo, M.;
    Persistent Identifiers
    Project: SNSF | New methods for next-gene... (PCEFP2_186879), RCUK | University of Sussex Astr... (ST/P000525/1), EC | COSMOPARS (616170)

    The cosmic microwave background (CMB) is gravitationally lensed by large-scale structure, which distorts observations of the primordial anisotropies in any given direction. Averaged over the sky, this important effect is routinely modelled with via the lensed CMB power ...

    Add to ORCID
  • publication . Preprint . Article . 2020
    Open Access
    Authors:
    Pierre-Aurelien M A Gilliot; Thomas E. Gorochowski;
    Publisher: MDPI AG
    Project: RCUK | EPSRC and BBSRC Centre fo... (EP/L016494/1), RCUK | BrisSynBio: Bristol Centr... (BB/L01386X/1)

    <jats:p>The ability to read and quantify nucleic acids such as DNA and RNA using sequencing technologies has revolutionized our understanding of life. With the emergence of synthetic biology, these tools are now being put to work in new ways - enabling de novo biologica...

    Add to ORCID
  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Andrew E. H. Wheatley; Susumu Saito; Lyu-Ming Wang; Hiroshi Naka; Kellie Jenkinson; Yuna Morioka;
    Persistent Identifiers
    Publisher: Nature Publishing Group UK
    Project: RCUK | DTA - University of Cambr... (EP/J500380/1)

    Abstract Direct functionalization of amino groups in complex organic molecules is one of the most important key technologies in modern organic synthesis, especially in the synthesis of bio-active chemicals and pharmaceuticals. Whereas numerous chemical reactions of amin...

    Add to ORCID
  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    Harry L. Anderson; Michael Jirásek; Hua-Wei Jiang; Laura M. Herz; Renée Haver; Lara Tejerina; Isabell Grübner; Hannah J. Eggimann; Michel Rickhaus;
    Persistent Identifiers
    Publisher: American Chemical Society (ACS)
    Project: RCUK | Supramolecular Nanorings ... (EP/M016110/1), SNSF | Porphyrin Spheres: p-Conj... (P2BSP2_168919), EC | SYNCHRONICS (643238), EC | MULTI-APP (642793), EC | COSUN (320969)

    <p>Most macrocycles are made from a simple repeat unit, resulting in high symmetry. Breaking this symmetry allows fine-tuning of the circumference, providing better control of the host&ndash;guest behavior and electronic structure. Here, we present the template-directed...

    Add to ORCID
  • publication . Article . Conference object . 2017
    Open Access
    Authors:
    Alexander Weng; J. McAnulty Robin; Josephine L. Barnes; Aristides D. Tagalakis; Stephen L. Hart; Maria Manunta; Mustafa M. Munye; Martin Attwood; Ahmed M. Aldossary;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: RCUK | Nanoparticles for the Tar... (EP/G061521/1), WT | Nanoparticles for topical... (094348)

    Abstract The inhibition of ENaC may have therapeutic potential in CF airways by reducing sodium hyperabsorption, restoring lung epithelial surface fluid levels, airway hydration and mucociliary function. The challenge has been to deliver siRNA to the lung with sufficien...

    Add to ORCID
  • publication . Article . Conference object . Other literature type . 2018
    Open Access
    Authors:
    Kerstin Brügemann; Chris Haley; M. Mahmoud; Masoud Shirali; T. Yin; S. König; Yanni Zeng;
    Publisher: Public Library of Science (PLoS)
    Project: RCUK | The Genetics of Complex a... (MC_PC_U127592696)

    Host genetic architecture is a major factor in resistance to pathogens and parasites. The collection and analysis of sufficient data on both disease resistance and host genetics has, however, been a major obstacle to dissection the genetics of resistance to single or mu...

    Add to ORCID
  • publication . Article . Conference object . 2017
    Open Access
    Authors:
    Milan Fernando; Giorgia Fanelli; Arifa Naeem; Steven H. Sacks; Conrad A. Farrar; Peter Garred; Robin R. Ali; Qi Peng; Peter J Gardner; Magdalena Kloc; ...
    Persistent Identifiers
    Publisher: Springer Nature
    Project: RCUK | A flow cytometry facility... (MR/L012758/1)

    Age-related macular degeneration (AMD) is a major cause of blindness and is associated with complement dysregulation. The disease is a potential target for stem cell therapy but success is<br/>likely to be limited by the inflammatory response. We investigated the innate...

    Add to ORCID
  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Luke C. Davies; James S. Griffiths; Diogo M. da Fonseca; Chia-Te Liao; Selinda J. Orr; Mathew Clement; Aiysha Thompson; Adam V. Jones; Gordon D. Brown; Ian R. Humphreys; ...
    Persistent Identifiers
    Publisher: Public Library of Science
    Project: RCUK | MRC Centre for Medical My... (MR/N006364/1), WT | Control of homeostasis an... (103973), WT | C-type lectins in antifun... (102705), NIH | PILOT--ANTIGENS AND T CEL... (1U54GM062116-01A1), WT | Understanding the molecul... (107964), WT , WT | Collaborative and redunda... (099953), WT | The role of innate immune... (207503)

    Author summary Fungal infections including invasive candidiasis are a serious healthcare problem particularly for immunocompromised patients. Mortality rates for invasive candidiasis are very high and complex anti-fungal immune responses are poorly understood, hindering...

    Add to ORCID
72,404 research outcomes, page 1 of 7,241