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271,765 research outcomes, page 1 of 27,177
  • publication . Article . 2020
    Open Access English
    Authors:
    Roshan Sharma; Rong Wang; Gouri Nanjangud; Yichi Xu; Peter F. Morgenstern; Shaghayegh Harbi; Martin Hemberg; Ashley M. Laughney; Monika Shpokayte; Monika Shpokayte; ...
    Publisher: Elsevier
    Project: NIH | Modeling pediatric glioma... (5R01CA208405-03), WT | Wellcome Trust Sanger Ins... (206194)

    Summary Radial glia (RG) cells are the first neural stem cells to appear during embryonic development. Adult human glioblastomas harbor a subpopulation of RG-like cells with typical RG morphology and markers. The cells exhibit the classic and unique mitotic behavior of ...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Anna Maria Masci; Heather Williams; David Birtwell; Christian J. Stoeckert; Mathias Brochhausen; Jie Zheng; Helena Judge Ellis;
    Persistent Identifiers
    Publisher: BioMed Central
    Project: NIH | Molecular Virology Core (5P30AI064518-07), NIH | Arkansas Center for Clini... (8UL1TR000039-04)

    Biobanking necessitates extensive integration of data to allow data analysis and specimen sharing. Ontologies have been demonstrated to be a promising approach in fostering better semantic integration of biobank-related data. Hitherto no ontology provided the coverage n...

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  • publication . Other literature type . Article . 2014
    Open Access
    Authors:
    Melissa L. Fishel; Thomas D. Hurley; Bibek Parajuli;
    Persistent Identifiers
    Publisher: American Chemical Society (ACS)
    Project: NIH | Activation and Inhibition... (5R01AA018123-03), NIH | Targeting ALDH2 for Adjuv... (1R21AA019746-01)

    Aldehyde dehydrogenase enzymes irreversibly oxidize aldehydes generated from metabolism of amino acids, fatty acids, food, smoke, additives, and xenobiotic drugs. Cyclophosphamide is one such xenobiotic used in cancer therapies. Upon activation, cyclophosphamide forms a...

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  • publication . Other literature type . Article . 2013
    Open Access English
    Authors:
    Ethan M. Lange; Keri L. Monda; Keri L. Monda; Wen Chi Hsueh; Yongmei Liu; Robert J. Weyant; Kimon Divaris; Kevin Moss; Silvana P. Barros; Lindsay M. Reynolds; ...
    Publisher: The University of North Carolina at Chapel Hill University Libraries
    Project: NIH | HEALTH ABC--COORDINATING ... (N01AG062106-019), NIH | Institute for Clinical an... (3UL1RR025005-03S2), NIH | Predicting Pulmonary Func... (1R01HL074104-01A1), NIH | DENTAL ATHEROSCLEROSIS RI... (3R01DE011551-03S1), NIH | UNC-CH Center for Environ... (5P30ES010126-11), NIH | Genetic Determinants of V... (1R01AG032098-01A1), NIH | DYNAMICS OF HEALTH .AGING... (N01AG062101-015), NIH | GWA for Gene-Environment ... (5U01HG004402-02), NIH | Genome-Wide Association f... (5R01HL087641-02), NIH | Epidemiology of Venous Th... (5R01HL059367-10),...

    Chronic periodontitis (CP) is a common oral disease that confers substantial systemic inflammatory and microbial burden and is a major cause of tooth loss. Here, we present the results of a genome-wide association study of CP that was carried out in a cohort of 4504 Eur...

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  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Stanley Perlman; Jian Zheng;
    Persistent Identifiers
    Publisher: Elsevier BV
    Project: NIH | Animal Core (5P01AI060699-10), NIH | Role of eicosanoids in pa... (5R01AI129269-03)

    Respiratory viruses, especially influenza A viruses and coronaviruses such as MERS-CoV, represent continuing global threats to human health. Despite significant advances, much needs to be learned. Recent studies in virology and immunology have improved our understanding...

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  • publication . Article . 2012
    Open Access
    Authors:
    Michele L. Allen; Ursula Reynoso; Jean L. Forster; Laura Trebs; Mary S. Marczak; Maria Veronica Svetaz; Monica Hurtado; Rose Allen; Katia Lopez-Petrovich; Cynthia S. Davey; ...
    Persistent Identifiers
    Publisher: Springer Nature
    Project: NIH | Minnesota Community Netwo... (3U54CA153603-04S2), NIH | Mayo Clinic Center for Cl... (3UL1RR024150-02S2)

    <p>Abstract</p> <p>Background</p> <p>Despite declines over recent years, youth tobacco and other substance use rates remain high. Latino youth are at equal or increased risk for lifetime tobacco, alcohol, marijuana, and other illicit drug use compared with their white p...

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  • publication . Article . 2014
    Open Access
    Authors:
    Anthony LaBarbera; Raul Andino; Mark Solovey; Tzachi Hagai; Leonid Gitlin;
    Persistent Identifiers
    Publisher: Public Library of Science (PLoS)
    Project: NIH | RNA Protein Interactions ... (5R01AI040085-07), NIH | Genetic Diversity as a De... (2R01AI036178-12)

    Nodamura Virus (NoV) is a nodavirus originally isolated from insects that can replicate in a wide variety of hosts, including mammals. Because of their simplicity and ability to replicate in many diverse hosts, NoV, and the Nodaviridae in general, provide a unique windo...

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  • publication . Article . 2013
    Open Access English
    Authors:
    William Chia; Phing Chian Chai; Zhong Liu; Yu Cai;
    Persistent Identifiers
    Publisher: Public Library of Science
    Project: NIH | Drosophila Transgenic RNA... (5R01GM084947-08)

    During the development of the Drosophila nervous system, the developmentally regulated Hedgehog pathway, together with a series of temporal transcription factors, schedules the end of neurogenesis.

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  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Brian J. Hall; Rachel Beanland; Weiping Cai; Haochu Li; Zachary C. Rich; Meg Doherty; Mellanye Lackey; Qingyan Ma; Fengyu Hu; Joseph D. Tucker; ...
    Publisher: International AIDS Society
    Project: NIH | UNC-South China STD Resea... (1D43TW009532-01), NIH | Spurring Innovation in HI... (1R01AI114310-01)

    Introduction : Qualitative research on antiretroviral therapy (ART) adherence interventions can provide a deeper understanding of intervention facilitators and barriers. This systematic review aims to synthesize qualitative evidence of interventions for improving ART ad...

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  • publication . Other literature type . Preprint . Article . 2019
    Open Access
    Authors:
    Yi Tang; Arthur Huang; Yang Hai;
    Publisher: Proceedings of the National Academy of Sciences
    Project: NIH | Discovery of Natural Prod... (1R35GM118056-01)

    <jats:title>ABSTRACT</jats:title><jats:p>Nonribosomal peptide synthetases (NRPS) and NRPS-like enzymes have diverse functions in primary and secondary metabolism. By using a structure-guided approach, we uncovered the function of an NRPS-like enzyme with unusual domain ...

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271,765 research outcomes, page 1 of 27,177