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661,539 research outcomes, page 1 of 66,154
  • publication . Other literature type . 2020
    Open Access German
    Authors:
    Hoefele, Joachim; Liste Lamas, Elsa; Konstantinidou, Triantafyllia Liana;
    Publisher: Universität Siegen
  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Dummer, Reinhard; Ascierto, Paolo A; Gogas, Helen J; Arance, Ana; Mandala, Mario; Liszkay, Gabriella; Garbe, Claus; Schadendorf, Dirk; Krajsova, Ivana; Gutzmer, Ralf; ...
    Publisher: Elsevier

    BACKGROUND Combined BRAF-MEK inhibitor therapy is the standard of care for BRAF-mutant advanced melanoma. We investigated encorafenib, a BRAF inhibitor with unique target-binding properties, alone or in combination with the MEK inhibitor binimetinib, versus vemurafenib ...

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  • publication . Article . Other literature type . 2007
    Open Access
    Authors:
    Hongwu He; Qingyun Ren; Chuan‐Fei Jin; Yu-Cheng Gu;
    Publisher: International Union of Crystallography (IUCr)

    In the title compound, C12H16N4O3, all bond lengths and angles are within normal ranges. An O—H⋯N and an N—H⋯O intra­molecular hydrogen bond contribute to the approximately planar mol­ecular conformation. In the crystal structure, inter­molecular N—H⋯O and N—H⋯N hydroge...

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  • publication . Article . 2019
    Open Access
    Authors:
    Appel, L. C.; Lupelli, I.; Abduallev, S.; Abhangi, M.; Abreu, P.; Afzal, M.; Aggarwal, K. M.; Ahlgren, T.; Ahn, J. H.; Aho-Mantila, L.; ...
    Project: EC | EUROfusion (633053)

    In many tokamaks ferromagnetic material, usually referred to as an iron-core, is present in order to improve the magnetic coupling between the solenoid and the plasma. The presence of the iron core in proximity to the plasma changes the magnetic topology with consequent...

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  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Milo A. Puhan; Anja Frei; Tsung Yu; Tsung Yu; Gerben ter Riet;
    Publisher: Nature Publishing Group UK
    Project: SNSF | Risk assessment for chron... (32333B-115216)

    Chronic lung disease: stay active to avoid depression and anxiety Patients with chronic lung disease who stay physically active could reduce their chances of depression and anxiety. Milo Puhan at the University of Zurich, Switzerland, and co-workers assessed the associa...

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  • publication . Part of book or chapter of book . Conference object . 2019
    Open Access
    Authors:
    Wolfgang Stoelzle; Victor Wildhaber;
    Publisher: Springer International Publishing

    The road freight transportation-industry in the German speaking countries (Germany, Austria and Switzerland) faces high market pressure. Besides a high competition between the logistic service providers, shippers are exerting pressure too (Cordes, 2018). The market situ...

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  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Qing Guo; Wen-Xue Li; Hyo-Jin Kim; Jin-Soo Kim; Long Jin; Cheng-Du Cui; Seokjoong Kim; Jin-Dan Kang; Xi-Jun Yin;
    Publisher: Impact Journals, LLC

    Pancreatic and duodenal homeobox 1 (PDX1) plays a crucial role in pancreas development, β-cell differentiation, and maintenance of mature β-cell function. In this study, we designed a strategy to produce PDX1-knockout (KO) pigs. A transcription activator-like effector n...

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  • publication . Preprint . 2018
    Open Access English
    Authors:
    Peter Kruczkiewicz; Federica Palma; Mirko Rossi; Dillon Or Barker; João A. Carriço; Eduardo N. Taboada;
    Publisher: Cold Spring Harbor Laboratory

    <jats:title>Abstract</jats:title><jats:p>Whole-genome sequencing (WGS) of microbial pathogens has become an essential part of modern epidemiological investigations. Although WGS data can be analyzed using a number of different approaches, such as traditional phylogeneti...

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  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Franziska Gerber; Rebecca Mott; Michael Lehning;
    Publisher: American Meteorological Society
    Project: SNSF | Snow-atmosphere interacti... (200021_150146), SNSF | The sensitivity of very s... (P300P2_164644)

    <jats:title>Abstract</jats:title> <jats:p>In this study, near-surface snow and graupel dynamics from formation to deposition are analyzed using WRF in a large-eddy configuration. The results reveal that a horizontal grid spacing of ≤50 m is required to resolve local oro...

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  • publication . Article . 2017
    Open Access
    Authors:
    Olaf Blanke; Olaf Blanke; Olaf Blanke; Roberta Ronchi; Roberta Ronchi; Andrea Serino; Andrea Serino; Lukas Heydrich;
    Publisher: British Psychological Society
    Project: EC | EPFL FELLOWS (291771), SNSF | NCCR SYNAPSY: The synapti... (51NF40_125759)

    The symptoms of patients with left personal neglect are characterized by inattention towards contralesional (left) body parts while at the same time explicitly ascertaining ownership for the neglected hemibody. It is currently unknown if personal neglect is associated w...

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661,539 research outcomes, page 1 of 66,154