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Gene-gene (GXG) and gene-environment (GXE) interactions play important roles in pharmacogenetics study. Simultaneously incorporating multiple single nucleotide polymorphisms (SNPs) and clinical factors is needed to explore the association of their interactions with drug response and toxicity phenotypes. We genotyped 504 SNPs in a total of 490 Chinese non-small cell lung cancer (NSCLC) patients, and the correlation of GXG and GXE interactions with platinum-based chemotherapeutic efficacy and safety were analyzed. In this data descriptor, we shared our data set which could help others to reuse them. All kinds of file types needed for GXG and GXE analysis were supplied. The process of genotyping and data analysis was also introduced step by step. Machine-accessible metadata file describing the reported data (ISA-Tab format)

At present, contracts are evolving to a collaborative form such as Integrated Project Delivery (IPD) or Multiparty agreements. Some states are using this new way of interaction to reduce fragmentation and self-interest of the AEC sector component. The construction sector’s productivity index is the same in the last decreased, on the contrary the one of the mechanic industry increased. Collaborative contracts are the way to improve the sector profitability. Its aim is to enable and develop collaboration between the owner, the designer and the constructors. New technologies evolution imposed a change in the contract type. A comparison between USA type and UK type is presented. This one is becoming a new standard for European contract. This new standard has proven to have demonstrated to generate an increase in productivity and a decrease in waste of time in the design, in construction and in operational phases. The changing of key participant’s scope from an individualist perspective to a collaborative one, it allow achieving the building quality. The project requirement is the necessity to better satisfy the owner needs, to clearly identify the contractual and extra-contractual responsibilities of individual operators. These are the reasons why Building Information Model and collaborative contracts are conceived to work on the same project.

The rock bream (Oplegnathus fasciatus) is one of the most economically valuable marine fish in East Asia, and due to various environmental factors, there is substantial revenue loss in the production sector. Therefore, knowledge of its genome is required to uncover the genetic factors and the solutions to these problems. In this study, we constructed the first draft genome of O. fasciatus as a reference for the family Oplegnathidae. The genome size is estimated to be 749 Mb, and it was assembled into 766 Mb by combining Illumina and PacBio sequences. A total of 24,053 transcripts (23,338 genes) are predicted, and among those transcripts, 23,362 (97%), are annotated with functional terms. Finally, the completeness of the genome assembly was assessed by CEGMA, which resulted in the complete mapping of 220 (88.7%) core genes in the genome. To the best of our knowledge, this is the first draft genome for the family Oplegnathidae. Machine-accessible metadata file describing the reported data (ISA-Tab format)

AbstractThree-dimensional motion capture analysis is considered the gold standard for any movement research. Motion capture data were recorded for 7 healthy female participants with no prior throwing experience to investigate the learning process for overarm throwing during a selected period. Participants were monitored 3 times a week for 5 weeks. Each session consisted of 15 dominant and 15 nondominant hand side overarm throws. A total of 3,150 trials were recorded and preprocessed (labeling reflective markers) for further analysis. The presented dataset can provide valuable information about upper extremity kinematics of the learning process of overarm throwing without any kind of feedback. Furthermore, this dataset may be used for more advanced analysis techniques, which could lead to more insightful information.

Neonatal seizures are a common emergency in the neonatal intensive care unit (NICU). There are many questions yet to be answered regarding the temporal/spatial characteristics of seizures from different pathologies, response to medication, effects on neurodevelopment and optimal detection. The dataset presented in this descriptor contains EEG recordings from human neonates, the visual interpretation of the EEG by the human experts, supporting clinical data and codes to assist access. Multi-channel EEG was recorded from 79 term neonates admitted to the NICU at the Helsinki University Hospital. The median recording duration was 74 min (IQR: 64 to 96 min). The presence of seizures in the EEGs was annotated independently by three experts. An average of 460 seizures were annotated per expert in the dataset; 39 neonates had seizures and 22 were seizure free, by consensus. The dataset can be used as a reference set of neonatal seizures, in studies of inter-observer agreement and for the development of automated methods of seizure detection and other EEG analyses. Machine-accessible metadata file describing the reported data (ISA-Tab format)

AbstractAnthropogenic emissions have substantially altered atmospheric acid and nutrient deposition in China. Understanding the status and characteristics of acid and nutrient deposition to China’s forests is crucial to assess the consequent impacts, and to better guide forest management options. Based on a comprehensive literature review, here I present an updated database for annual acid and nutrient deposition during the period 1991-2015 in China’s forests (CFAND 2.0). The database includes information from 56 forested sites on the water fluxes of bulk precipitation and throughfall, the concentrations of H+ (pH), dissolved inorganic nitrogen (N) (NH4+ and NO3−), sulfur (S), dissolved phosphorus (P), potassium (K+), calcium (Ca2+) and magnesium (Mg2+) in bulk precipitation and throughfall, and the fluxes of dissolved inorganic N, S, dissolved P, K+, Ca2+ and Mg2+ in bulk deposition and throughfall. This database will help to understand the spatial patterns of acid and nutrient deposition, validate modelling results of acid and nutrient deposition and assess the ecological effects of acid and nutrient deposition in China’s forests.

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016. Story collected by a student at Knockerra (C.), Killimer school (Knockerra, Co. Clare) from informant Mrs E. Culligan. Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Eibhlín Ní Cholgain.

MgBe4Cu is Hexagonal Laves-derived structured and crystallizes in the cubic F-43m space group. The structure is three-dimensional. Mg is bonded in a 4-coordinate geometry to twelve equivalent Be and four equivalent Cu atoms. All Mg–Be bond lengths are 2.59 Å. All Mg–Cu bond lengths are 2.71 Å. Be is bonded to three equivalent Mg, six equivalent Be, and three equivalent Cu atoms to form a mixture of edge, face, and corner-sharing BeMg3Be6Cu3 cuboctahedra. There are three shorter (2.18 Å) and three longer (2.23 Å) Be–Be bond lengths. All Be–Cu bond lengths are 2.59 Å. Cu is bonded in a 4-coordinate geometry to four equivalent Mg and twelve equivalent Be atoms.