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87,073 research outcomes, page 1 of 8,708
  • publication . Article . 2016
    Restricted
    Authors:
    Marie Miglianico; Gerry A. F. Nicolaes; Dietbert Neumann;
    Persistent Identifiers

    As a central regulator of metabolism, the AMP-activated protein kinase (AMPK) is an established therapeutic target for metabolic diseases. Beyond the metabolic area, the number of medical fields that involve AMPK grows continuously, expanding the potential applications ...

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  • publication . Article . Preprint . Other literature type . 2015
    Open Access English
    Authors:
    Christophe Hurlin; Sébastien Laurent; Rogier Quaedvlieg; Stephan Smeekes;

    Fichier WP en ligne ; International audience; We propose a bootstrap-based test of the null hypothesis of equality of two firms? conditional Risk Measures (RMs) at a single point in time. The test can be applied to a wide class of conditional risk measures issued from p...

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  • publication . Article . 2016
    Open Access English
    Authors:
    N. N. J. J. M. van der Sluiszen; Annemiek Vermeeren; Stefan Jongen; Eef L. Theunissen; A. van Oers; C. J. Van Leeuwen; A. Maret; C. Desforges; A. Delarue; Johannes G. Ramaekers;
    Persistent Identifiers

    OBJECTIVE: Previous studies demonstrated that mequitazine produces mild sedation after single doses. Its enantiomer, l-mequitazine, has a stronger potency for the H1 receptor. The aim of the current study was to assess the effects of l-mequitazine and mequitazine, alone...

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  • publication . Article . 2015
    Open Access English
    Authors:
    A.J. Bensdorp; R.I. Tjon-Kon-Fat; Patrick M.M. Bossuyt; C.A.M. Koks; G.J.E. Oosterhuis; Annemieke Hoek; Peter G.A. Hompes; F.J.M. Broekmans; Harold R. Verhoeve; J.P. de Bruin; ...
    Persistent Identifiers
    Publisher: BMJ Publishing Group Ltd.

    Objectives: To compare the effectiveness of in vitro fertilisation with single embryo transfer or in vitro fertilisation in a modified natural cycle with that of intrauterine insemination with controlled ovarian hyperstimulation in terms of a healthy child. Design: Mult...

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  • publication . Article . 2005
    Open Access
    Authors:
    E. J. Wagena; P. G. Knipschild; Marcus J.H. Huibers; Emiel F.M. Wouters; C.P. van Schayck;
    Publisher: Elsevier BV

    Background The observations that smokers with chronic obstructive pulmonary disease (COPD) are at increased risk of depression and that nicotine may have antidepressant effects and regulate mood provide a rationale for the use of antidepressant drugs for smoking cessati...

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  • publication . Article . Preprint . 2010
    Open Access English
    Authors:
    Frank Lutgens; Peter C. Schotman;
    Persistent Identifiers

    We consider mean-variance portfolio choice of a robust investor. The investor receives advice from J experts, each with a different prior for the distribution of returns. Confronted with these multiple priors the investor follows a min-max portfolio strategy. We study t...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Nina Tupper; Melanie Sauerland; James D. Sauer; Lorraine Hope;
    Persistent Identifiers

    A considerable proportion of crimes that involve multiple perpetrators. Yet, little is known about how police officers construct, administer, and record eyewitness identification procedures for multiple suspects. An online survey of law enforcement agents in Sweden, Bel...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Rena Gatzounis; Ann Meulders;
    Persistent Identifiers

    In exposure for chronic pain, avoidance is often forbidden (extinction with response prevention; RPE) to prevent misattributions of safety. Although exposure is an effective treatment, relapse is common. Little is known about the underlying mechanisms of return of pain-...

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  • publication . Article . 2007
    Open Access
    Authors:
    Henk M. De Feyter; Stephan F. E. Praet; Nicole M. A. van den Broek; Harm Kuipers; Coen D.A. Stehouwer; Klaas Nicolay; Jeanine J. Prompers; Luc J. C. van Loon;
    Persistent Identifiers
    Publisher: American Diabetes Association

    Regular exercise represents an effective strategy to prevent and/or treat type 2 diabetes (1,2). However, the clinical benefits of exercise intervention in a vastly expanding group of long-standing insulin-treated type 2 diabetic patients with comorbidities are less evi...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Bunmi S. Malau-Aduli; Peta-Ann Teague; Richard Turner; Benjamin W.B. Holman; Karen D'Souza; David L Garne; Clare Heal; Paula Heggarty; Judith N Hudson; Ian G Wilson; ...
    Persistent Identifiers

    BACKGROUND: This study was undertaken to improve assessment practice on OSCEs through collaboration across geographically dispersed medical schools in Australia. METHODS: A total of eleven OSCE stations were co-developed by four medical schools and used in summative 201...

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87,073 research outcomes, page 1 of 8,708