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788 research outcomes, page 1 of 79
  • publication . Article . 2010
    Open Access English
    Authors:
    Mike L. Smith; Mark J Dunning; Simon Tavaré; Andy G. Lynch;
    Persistent Identifiers
    Publisher: BMC

    Abstract Background A key stage for all microarray analyses is the extraction of feature-intensities from an image. If this step goes wrong, then subsequent preprocessing and processing stages will stand little chance of rectifying the matter. Illumina employ random con...

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  • publication . Article . 2018
    Open Access English
    Authors:
    Leonid Chindelevitch; João Paulo Pereira Zanetti; João Meidanis;
    Persistent Identifiers
    Publisher: BioMed Central
    Project: CIHR

    Background Recently, Pereira Zanetti, Biller and Meidanis have proposed a new definition of a rearrangement distance between genomes. In this formulation, each genome is represented as a matrix, and the distance d is the rank distance between these matrices. Although de...

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  • publication . Article . 2013
    Open Access English
    Authors:
    Zsuzsanna Sükösd; Bjarne Knudsen; James W. J. Anderson; Adam M. Novak; Jørgen Kjems; Christian N. S. Pedersen;
    Persistent Identifiers

    Comparative methods for RNA secondary structure prediction use evolutionary information from RNA alignments to increase prediction accuracy. The model is often described in terms of stochastic context-free grammars (SCFGs), which generate a probability distribution over...

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  • publication . Article . Other literature type . Preprint . 2021
    Open Access English
    Authors:
    Miller, Eleanor F.; Manica, Andrea;
    Publisher: BMC

    Background: Today an unprecedented amount of genetic sequence data is stored in publicly 11 available repositories. For decades now, mitochondrial DNA (mtDNA) has been the workhorse of 12 genetic studies, and as a result, there is a large volume of mtDNA data available ...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Narayan Jayaram; Daniel Usvyat; Andrew J. Martin;
    Persistent Identifiers
    Publisher: BioMed Central

    Background Binding of transcription factors to transcription factor binding sites (TFBSs) is key to the mediation of transcriptional regulation. Information on experimentally validated functional TFBSs is limited and consequently there is a need for accurate prediction ...

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  • publication . Article . 2013
    Open Access English
    Authors:
    Sean Hoban; Massimo Mezzavilla; Oscar E. Gaggiotti; Andrea Benazzo; Cock van Oosterhout; Giorgio Bertorelle;
    Persistent Identifiers
    Publisher: BioMed Central

    Funding was provided by the University of Ferrara, Italy. CvO was funded by the Earth and Life Systems Alliance (ELSA), Norwich Research Park, UK Background: Demographic bottlenecks can severely reduce the genetic variation of a population or a species. Establishing whe...

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  • publication . Article . 2005
    Open Access English
    Authors:
    Younes Mokrab; Kenji Mizuguchi;
    Persistent Identifiers
    Publisher: BMC

    RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make com...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Stevenn Volant; Pierre Lechat; Perrine Woringer; Laurence Motreff; Pascal Campagne; Christophe Malabat; Sean Kennedy; Amine Ghozlane;
    Persistent Identifiers
    Publisher: HAL CCSD

    Abstract Background Comparing the composition of microbial communities among groups of interest (e.g., patients vs healthy individuals) is a central aspect in microbiome research. It typically involves sequencing, data processing, statistical analysis and graphical disp...

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  • publication . Article . 2009
    Open Access English
    Authors:
    Mattias Rantalainen; Olivier Cloarec; Timothy M. D. Ebbels; Torbjörn Lundstedt; Jeremy K. Nicholson; Elaine Holmes; Johan Trygg;
    Persistent Identifiers
    Publisher: Springer Nature

    Background: Modelling the time-related behaviour of biological systems is essential for understanding their dynamic responses to perturbations. In metabolic profiling studies, the sampling rate and number of sampling points are often restricted due to experimental and...

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  • publication . Article . 2008
    Open Access English
    Authors:
    Jonathan D. Moore; Shelagh Kell; José M. Iriondo; Brian Ford-Lloyd; Nigel Maxted;
    Persistent Identifiers
    Publisher: BioMed Central Ltd.

    Abstract Background Crop wild relatives are wild species that are closely related to crops. They are valuable as potential gene donors for crop improvement and may help to ensure food security for the future. However, they are becoming increasingly threatened in the wil...

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788 research outcomes, page 1 of 79