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935 research outcomes, page 1 of 94
  • publication . Article . 2010
    Open Access English
    Authors:
    Martial Hue; Michael Riffle; Jean-Philippe Vert; William Stafford Noble;
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: NIH | DETERMINATION OF IN VIVO ... (5P41RR011823-04)

    Abstract Background The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms inside the cell. While experimental methods for identifying these interactions remain c...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Solon P. Pissis;
    Persistent Identifiers
    Publisher: Springer Nature

    Background Identifying repeated factors that occur in a string of letters or common factors that occur in a set of strings represents an important task in computer science and biology. Such patterns are called motifs, and the process of identifying them is called motif ...

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  • publication . Article . 2010
    Open Access English
    Authors:
    Harald Barsnes; Richard G. Côté; Ingvar Eidhammer; Lennart Martens;
    Publisher: BioMed Central
    Project: WT

    Abstract Background With the growing amount of biomedical data available in public databases it has become increasingly important to annotate data in a consistent way in order to allow easy access to this rich source of information. Annotating the data using controlled ...

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  • publication . Article . Other literature type . 2008
    Open Access English
    Authors:
    Rouchka, Eric C; Krushkal, Julia; Goldowitz, Daniel;
    Publisher: Springer Nature
    Project: NIH | Annual UT-ORNL-KBRIN Bioi... (5R13LM009315-02), NIH | Kentucky Biomedical Resea... (5P20RR016481-03)

    In this meeting report we give an overview of the talks and presentations from the Fourth International Society for Computational Biology (ISCB) Student Council Symposium held as part of the annual Intelligent Systems for Molecular Biology (ISMB) conference in Toronto, ...

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  • publication . Article . 2011
    Open Access English
    Authors:
    Gustavo A. Salazar; Rafael C. Jimenez; Alexander Garcia; Henning Hermjakob; Nicola Mulder; Edwin Blake;
    Persistent Identifiers
    Publisher: Springer Nature
    Project: EC | APO-SYS (200767)

    Abstract Background Centralised resources such as GenBank and UniProt are perfect examples of the major international efforts that have been made to integrate and share biological information. However, additional data that adds value to these resources needs a simple an...

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  • publication . Article . 2013
    Open Access English
    Authors:
    Gregoire Pau; Thomas Walter; Beate Neumann; Jean-Karim Hériché; Jan Ellenberg; Wolfgang Huber;
    Persistent Identifiers
    Publisher: HAL CCSD

    Abstract Background The combination of time-lapse imaging of live cells with high-throughput perturbation assays is a powerful tool for genetics and cell biology. The Mitocheck project employed this technique to associate thousands of genes with transient biological ph...

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  • publication . Article . 2011
    Open Access English
    Authors:
    Peter Sykacek; David P. Kreil; Lisa A. Meadows; Richard P. Auburn; Bettina Fischer; Steven Russell; Gos Micklem;
    Persistent Identifiers
    Publisher: BioMed Central
    Project: WT | An integrated database fo... (067205), UKRI | Genetic, Genomic and Mole... (G8225539)

    Abstract Background With the growing availability of entire genome sequences, an increasing number of scientists can exploit oligonucleotide microarrays for genome-scale expression studies. While probe-design is a major research area, relatively little work has been rep...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Rhys A. Farrer;
    Persistent Identifiers
    Publisher: BioMed Central
    Project: WT , WT | Studying the evolution of... (101774)

    Ortholog prediction and synteny visualization across whole genomes are valuable methods for detecting and representing a range of evolutionary processes such as genome expansion, chromosomal rearrangement, and chromosomal translocation. Few standalone methods are curren...

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  • publication . Article . 2015
    Open Access English
    Authors:
    Jorge Júlvez;
    Project: EC | FORMALBIO (623995)

    Background: Many biological systems exhibit sustained stochastic oscillations in their steady state. Assessing these oscillations is usually a challenging task due to the potential variability of the amplitude and frequency of the oscillations over time. As a result of ...

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  • publication . Article . 2020
    Open Access English
    Authors:
    Lin Zhang; Shutao Chen; Jingyi Zhu; Jia Meng; Hui Liu;
    Persistent Identifiers
    Publisher: BioMed Central

    Abstract Background Recent studies have shown that N6-methyladenosine (m6A) plays a critical role in numbers of biological processes and complex human diseases. However, the regulatory mechanisms of most methylation sites remain uncharted. Thus, in-depth study of the e...

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935 research outcomes, page 1 of 94