Filters (3 )
Download Results
49 research outcomes, page 1 of 5
  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Stefan Kääb; Carolina Roselli; Jie Yao; Marcus Dörr; Alvaro Alonso; Fernando Rivadeneira; Peter van der Meer; Magdalena Zoledziewska; Paul L. Huang; Yi-Ping Fu; ...
    Project: NIH | Robust Software Tools for... (3U01HG006513-02S2), NIH | Gene Discovery for Warfar... (5R01NS059727-02), EC | MOvE-ECG (661395), NIH | CHS Events Follow-up Stud... (1U01HL080295-01), NWO | NCHA Subsidiebesluit 2008... (2300155116), RCUK | MICA: Medical Bioinformat... (MR/L016311/1), NIH | Exceptional aging: 12 yea... (5R01AG023629-03), NIH | MESA Family Study (3R01HL071251-01A1S1), NIH | OBESITY, DIABETES &AGING ... (N01AG002100-001), WT | Wellcome Trust Sanger Ins... (098051),...

    © The Author 2017. Published by Oxford University Press. Resting heart rate is a heritable trait, and an increase in heart rate is associated with increased mortality risk. Genome-wide association study analyses have found loci associated with resting heart rate, at the...

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Audrey C. Choh; Nina Smolej Narančić; Claire Bellis; Ben A. Oostra; Robert A. Scott; Lisette C. P. G. M. de Groot; Steven R. Cummings; David A. Bennett; Lavinia Paternoster; Stéphane Lobbens; ...
    Publisher: Uppsala universitet, Molekylär epidemiologi
    Project: EC | METABOLICPOLYCOMBICS (281641), EC | ePerMed (692145), WT

    A genome-wide association meta-analysis study here shows novel genetic loci to be associated to body fat percentage, and describes cross-phenotype association that further demonstrate a close relationship between adiposity and cardiovascular disease risk.

  • publication . Article . Other literature type . 2011
    Open Access English
    Authors:
    Mulligan Anna Marie; Couch Fergus J; Barrowdale Daniel; Domchek Susan M; Eccles Diana; Nevanlinna Heli; Ramus Susan J; Robson Mark; Sherman Mark; Spurdle Amanda B; ...
    Publisher: Springer Nature
    Project: NIH | Fox Chase Clinical Epidem... (3U01CA113916-05S1), NIH | Ontario Familial Breast C... (5U01CA069467-16), NIH | COOPERATIVE BREAST CANCER... (5U01CA069446-03), EC | FIGHTINGDRUGFAILURE (238132), NIH | Australian Breast Cancer ... (5U01CA069638-16), NIH | A genome-wide association... (5R01CA128978-02), NIH | BRCA2 missense mutations ... (1R01CA116167-01A1), NIH | SPORE in Breast Cancer (5P50CA058207-12), AKA | GENETIC SUSCEPTIBILITY TO... (132473), NIH | COMPREHENSIVE FAMILIAL BR... (5U01CA069631-05),...

    [Introduction]: Previous studies have demonstrated that common breast cancer susceptibility alleles are differentially associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers. It is currently unknown how these alleles are associated with different br...

  • publication . Article . Other literature type . 1993
    Open Access English
    Authors:
    Udo Schumacher; Hans-Peter Horny; Karl Skírnisson; Günter Heidemann; Ulrich Welsch; Stefan Zahler;

    In 1988 and 1989, thousands of harbor seals (Phoca vitulina) died in the North Sea from phocine distemper infection. The morphology of thyroid glands from 40 harbor seals found dead on the North Sea coastlines of Schleswig-Holstein, Federal Republic of Germany, during a...

  • publication . Other literature type . Article . 2017
    Open Access English
    Authors:
    Kari E. North; Weihua Zhang; Weihua Zhang; Kristin L. Young; Anne E. Justice; Reija Männikkö; John-Olov Jansson; Stephanie A. Bien; Kai Savonen; Yii Der Ida Chen; ...
    Publisher: The University of North Carolina at Chapel Hill University Libraries
    Project: NHMRC | Genome-wide combined link... (389891), NIH | Targeted Genetic Analysis... (2R01DK072193-10), NWO | Tracking Emerging Adults,... (2300168342), NWO | NCHA Subsidiebesluit 2008... (2300155116), NHMRC | Investigating the role of... (552485), NHMRC | Genetics of melanoma risk... (389875), RCUK | Identification of genetic... (G0700931), NIH | GENOTYPING FOR LOCATING H... (N01HG065403-001), NIH | FIELD CENTER FOR CCSP (N01HC055019-009), NIH | Cardiovascular Epidemiolo... (2T32HL007055-36),...

    Few genome-wide association studies (GWAS) account for environmental exposures, like smoking, potentially impacting the overall trait variance when investigating the genetic contribution to obesity-related traits. Here, we use GWAS data from 51,080 current smokers and 1...

  • publication . Article . 2015
    Open Access English
    Authors:
    Christina Willenborg; Jorma Viikari; Andrew P. Morris; Chris Power; Teresa Ferreira; Jouke-Jan Hottenga; P. Eline Slagboom; Aaron Isaacs; Leif Groop; Leif Groop; ...
    Publisher: Public Library of Science
    Project: NIH | Major Depression: Stage 1... (1R01MH081802-01), NWO | NCHA Subsidiebesluit 2008... (2300155116), WT | Candidate gene variation ... (069224), NIH | Genetics of cardiovascula... (5R01HL087679-02), AKA | Preterm birth and early l... (127437), NIH | Integration of Genomics &... (1RC2MH089951-01), AKA | Early growth, genes, and ... (213225), AKA | Early growth, genes and g... (114382), EC | GMI (230374), NIH | Whole Genome Assoc. Analy... (1RL1MH083268-01),...

    Author Summary Human genetic studies have demonstrated that quantitative human anthropometric and metabolic traits, including body mass index, waist-hip ratio, and plasma concentrations of glucose and insulin, are highly heritable, and are established risk factors for t...

  • publication . Article . Other literature type . Preprint . 2018
    Open Access English
    Authors:
    Jose G. Para; Jonas Bybjerg-Grauholm; Katherine Gordon-Smith; Boomsma, Dorret, I; Carsten Bøcker Pedersen; Stéphane Jamain; Sarah E. Bergen; Stephan Ripke; David Craig; Gerome Breen; ...
    Publisher: Springer Nature
    Project: EC | TRIP (295192), RCUK | Centre for Health service... (MR/K006584/1), EC | BBFGEN (658195), WT

    Simone de Jong et al. examine the balance of common and rare risk for psychiatric disorders in a large family with high incidence of Bipolar Disorder and Major Depressive Disorder. They find that increased polygenic risk over generations could be partially due to assort...

  • publication . Article . 2017
    Open Access English
    Authors:
    Chantal Raherison; Vivi Schlünssen; Christer Janson; Sandra Dorado Arenas; Pascal Demoly; Thorarinn Gislason; Anne Elie Carsin; Anne Elie Carsin; Judith Garcia-Aymerich; Judith Garcia-Aymerich; ...
    Publisher: BMJ Publishing Group
    Project: EC | ALEC (633212)

    The ALEC Study is funded by the European Union's Horizon 2020 Research and Innovation programme under grant agreement No 633212.

  • publication . Article . Other literature type . Conference object . 2019
    Open Access English
    Authors:
    Yasaman Saba; S Yamaguchi; Michelle Luciano; Martin Dichgans; Christophe Tzourio; Michael Griswold; S. Muñoz Maniega; S. Muñoz Maniega; Michele L. Callisaya; B B Worrall; ...
    Publisher: HAL CCSD
    Project: NIH | ALZHEIMERS DISEASE DATA C... (5U01AG016976-03), NIH | Preclinical AD: Correlate... (5R01AG049607-05), NIH | UCLA Alzheimers Disease R... (3P50AG016570-07S1), NHMRC | Unravelling the genetic c... (1063960), NIH | ROLE FOR FIBROBLAST GROWT... (3P30AG012300-06S1), NIH | Biomarkers in Early Alzhe... (5R01AG022374-05), NIH | White matter damage in ag... (3R01AG031892-05S1), NIH | Genetic Associations with... (5R01AG026916-02), NIH | Systematic identification... (1DP3DK111906-01), NIH | Nonlinear Models of Cogni... (1R01AG051635-01A1),...

    Objective: To explore genetic and lifestyle risk factors of MRI-defined brain infarcts (BI) in large population-based cohorts. Methods We performed meta-analyses of genome-wide association studies (GWAS) and examined associations of vascular risk factors and their genet...

  • publication . Article . 2003
    Open Access English
    Authors:
    Tomas Jelinek; Vienxay Vanisaveth; Sabine Dittrich; Sabine Jordan; Babett Schwöbel; Samlane Phompida; Phetsouvanh Rattanaxay; Eva Maria Christophel;
    Publisher: Ludwig-Maximilians-Universität München

    <p>Abstract</p> <p>Background</p> <p>The erythrocyte binding antigen 175 (EBA-175) is a 175 kDa antigen of <it>Plasmodium falciparum </it>and plays a major role in erythrocyte recognition by the parasite. The antigen is also supposed to be partly responsible for the inv...

49 research outcomes, page 1 of 5