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- publication . Article . 2020Open Access EnglishAuthors:Mohamed O. Mahmoud; Rofaida Gaballa; Zakaria Y. Abd Elmageed; Hamdy E.A. Ali; Stefan Ambs; Johng S. Rhim; Hamed I. Ali; Mohammad Saleem; Mohamed A. Kandeil; Heba F. Salem;pmc: PMC7466113pmid: 32824235Publisher: MDPI AG
<jats:p>Although integrin alpha 2 subunit (ITGA2) mediates cancer progression and metastasis, its transfer by exosomes has not been investigated in prostate cancer (PCa). We aimed to determine the role of exosomal ITGA2 derived from castration-resistant PCa (CRPC) cells...
- publication . Article . 2020Open Access EnglishAuthors:Reham Samir Hamida; Mashael Mohammed Bin-Meferij; Gadah Albasher;pmc: PMC7464693pmid: 32731591Publisher: MDPI AG
<jats:p>Green nanoparticles represent a revolution in bionanotechnology, providing opportunities to fight life-threatening diseases, such as cancer, with less risk to the environment and to human health. Here, for the first time, we systematically investigated the antic...
- publication . Other literature type . Article . 2019Open AccessAuthors:Amira Osman; Kazuki Kumon; Nobuhiro Okada; Juan Du; Said M. Afify; Ayano Satoh; Maram H. Zahra; Hager M. Mansour; Ghmkin Hassan; Akimasa Seno; ...pmid: 31905766pmc: PMC7016803Publisher: MDPI AG
Cancer stem cells (CSCs) represent the subpopulation of cancer cells with the ability to differentiate into other cell phenotypes and initiated tumorigenesis. Previously, we reported generating CSCs from mouse induced pluripotent stem cells (miPSCs). Here, we investigat...
- publication . Article . Other literature type . 2019Open AccessAuthors:Jung-Hye Choi; Hwi-Ho Lee; Ji-Sun Shin; Kyung-Tae Lee; Joo Young Hong; Hyo-Sun Gil; Yong Sup Lee; Ahmed H.E. Hassan; Ahmed H.E. Hassan; Eunwoo Choi; ...pmc: PMC6966466pmid: 31816985Publisher: MDPI AG
We previously reported the potential anti-proliferative activity of 3-(5,6,7-trimethoxy-4-oxo-4H-chromen-2-yl)-N-(3,4,5-trimethoxyphenyl) benzamide (TMS-TMF-4f) against human cancer cells
- publication . Article . Other literature type . 2020Open AccessAuthors:Neveen Said; Ammar Yasser Abdulfattah; Ammar Yasser Abdulfattah; Daniela Gonzalez; Alia Ghoneum;pmc: PMC7281273pmid: 32429566Publisher: MDPI AG
Ovarian Cancer is the fifth most common cancer in females and remains the most lethal gynecological malignancy as most patients are diagnosed at late stages of the disease. Despite initial responses to therapy, recurrence of chemo-resistant disease is common. The presen...
- publication . Article . Other literature type . 2018Open Access EnglishAuthors:Ahmed T. El-Serafi; Aya Mudhafar Al-Azawi; Raafat El-Awady; Wafaa S. Ramadan; Varsha Menon; Wael Y. Mansour; Cijo George Vazhappilly; Ekram M. Saleh;pmc: PMC6356506pmid: 30583472Publisher: MDPI
and HER2/ERBB2 along with (ii) an increase in the sensitivity of TNBC cells to tamoxifen. Collectively, this study indicates a different epigenetic background for TNBC cells, which represses the expression of ER&alpha
- publication . Article . Other literature type . 2011Open AccessAuthors:Amany M. Ali; Mohamed Salem; Hesham M. Hamza; Heba A. Sayd;pmc: PMC3757380pmid: 24212775Publisher: MDPI AG
abdominal emergencies, diagnostic biopsy and total tumor extirpation in localized disease. Chemotherapy is the cornerstone in the management of pediatric abdominal NHL.
- publication . Article . Other literature type . 2020Open Access EnglishAuthors:Stanislaw Gierlotka; Olfat G. Shaker; Julita Smalc-Koziorowska; Khaled AbouAitah; Witold Lojkowski; Jacek Wojnarowicz; Anna Swiderska-Sroda; Lamiaa Gohar; Agnieszka Opalinska; Heba A. Hassan;pmc: PMC7017376pmid: 31936103Publisher: MDPI AG
HepG2 (liver cancer) >
- publication . Article . 2020Open Access EnglishAuthors:Basant Salah Mahmoud; Christopher McConville; Ali Hamod AlAmri;pmc: PMC7017235pmid: 31936740Publisher: MDPI AG
<jats:p>Malignant gliomas are one of the deadliest forms of brain cancer and despite advancements in treatment, patient prognosis remains poor, with an average survival of 15 months. Treatment using conventional chemotherapy does not deliver the required drug dose to th...
- publication . Article . Other literature type . 2020Open Access EnglishAuthors:Ravi Vij; Mark A. Fiala; Barbara Muz; Shannon Gurley; Justin King; Jennifer Sun; Matea Markovic; Daniel Kohnen; Kinan Alhallak; Noha N. Salama; ...pmc: PMC7072283pmid: 32012878Publisher: MDPIProject: NIH | Developmental Project (1U54CA199092-01), NIH | Washington University Ins... (1TL1TR002344-01)
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