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82 research outcomes, page 1 of 9
  • publication . Article . Other literature type . 2007
    Open Access English
    Authors:
    Christian Ruff;
    Project: WT

    It has often been proposed that regions of the human parietal and/or frontal lobe may modulate activity in visual cortex, for example, during selective attention or saccade preparation. However, direct evidence for such causal claims is largely missing in human studies,...

  • publication . Article . 2016
    Open Access
    Authors:
    Thomas Krausgruber; Krista Stockenhuber; Andreas Heger; Nicholas Ilott; Chris Schiering; Camille Danne;
    Publisher: Springer Science and Business Media LLC
    Project: WT | Immune pathways in the in... (095688), WT | Understanding the genetic... (090532)

    <jats:title>Abstract</jats:title> <jats:p>The gut microbiome is significantly altered in inflammatory bowel diseases, but the basis of these changes is not well understood. We have combined metagenomic and metatranscriptomic profiling of the gut microbiome to assess mod...

  • publication . Article . 2017
    Open Access English
    Authors:
    Flinn, L.J; Keatinge, M; Bretaud, S; Mortiboys, H; Matsui, H; De Felice, E; Woodroof, H.I; Brown, L; McTighe, A; Soellner, R; ...
    Publisher: Wiley-Liss
    Project: WT | The synaptic physiology o... (083601), RCUK | BBSRC Industrial CASE Par... (BB/I532553/1)

    Objective: Loss of function mutations in PINK1 typically lead to early onset Parkinson disease (PD). Zebrafish (Danio rerio) are emerging as a powerful new vertebrate model to study neurodegenerative diseases. We used a pink1 mutant (pink−/−) zebrafish line with a prema...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Thaker, Youg Raj; Raab, Monika; Strebhardt, Klaus; Rudd, Christopher E.;
    Project: WT | Signalling in T-cell immu... (092627)

    Immunotherapy involving checkpoint blockades of inhibitory co-receptors is effective in combating cancer. Despite this, the full range of mediators that inhibit T-cell activation and influence anti-tumor immunity is unclear. Here, we identify the GTPase-activating prote...

  • publication . Article . Review . 2019
    Open Access
    Authors:
    Matthieu Muffato; Mateus Patricio; Christophe Dessimoz; Paul D. Thomas; Alan Wilter Sousa da Silva; Yan Wang; Maria-Jesus Martin;
    Publisher: Oxford University Press (OUP)
    Project: NIH | Mapping the blood cell pr... (1R01DK110520-01), NIH | Proteomics and model orga... (5R35GM122480-03), EC | ELIXIR-EXCELERATE (676559), NIH | UniProt: A centralized pr... (3U41HG007822-04S1), NIH | Mapping the CPLANE intera... (5R01HD085901-02), NIH | Gene Ontology Consortium (5P41HG002273-08), WT | ENSEMBL (108749), SNSF | Harnessing Phylogenetic V... (PP00P3_150654), NIH | Proteomics of ciliopathy ... (5F31GM123683-02)

    <jats:title>Abstract</jats:title> <jats:p>Gene families evolve by the processes of speciation (creating orthologs), gene duplication (paralogs), and horizontal gene transfer (xenologs), in addition to sequence divergence and gene loss. Orthologs in particular play an es...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Lorenzo Cordani; Enzo Tagliazucchi; Céline Vetter; Christian Hassemer; Till Roenneberg; Jörg H. Stehle; Christian A. Kell;
    Project: WT

    Visual perception depends on light—which changes according to time of day—but the accompanying neural changes are unknown. Here, authors use fMRI to describe the brain dynamics underlying visual perception and find that sensory areas change their activity to compensate ...

  • publication . Article . 2013
    Open Access
    Authors:
    Martyn, Amelia J.; Seed, Leahwyn U.; Mark Ooi; Offord, Catherine A.;
    Project: WT

    The New South Wales Seedbank (at Mount Annan Botanic Garden) stores seeds of both common and threatened species for conservation, research and restoration or revegetation projects. The value of the collections depends on our ability to germinate seeds once they have bee...

  • publication . Article . 2018
    Open Access English
    Authors:
    Mari Anneli Kaunisto; Jorn Lotsch;
    Project: EC | GLORIA (602919), WT

    Background: Many gene variants modulate the individual perception of pain and possibly also its persistence. The limited selection of single functional variants is increasingly being replaced by analyses of the full coding and regulatory sequences of pain-relevant genes...

  • publication . Article . 2012
    Open Access English
    Authors:
    Christian Fiebach;
    Publisher: Springer-Verlag
    Project: WT

    The present study investigates the effects of trait anxiety on the neural efficiency of working memory component functions (manipulation vs. maintenance) in the absence of threat-related stimuli. For the manipulation of affectively neutral verbal information held in wor...

  • publication . Article . Other literature type . 2010
    Open Access English
    Authors:
    Christian Ruff;
    Publisher: OXFORD UNIV PRESS INC
    Project: EC | BRAINSYNC (200728), WT

    Combining transcranial magnetic stimulation (TMS) with concurrent functional magnetic resonance imaging (fMRI) allows study of how local brain stimulation may causally affect activity in remote brain regions. Here, we applied bursts of high- or low-intensity TMS over ri...

82 research outcomes, page 1 of 9
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