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658 research outcomes, page 1 of 66
  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Brian Godman; Brian Godman; Brian Godman; Brian Godman; Anna Bucsics; Patricia Vella Bonanno; Wija Oortwijn; Wija Oortwijn; Celia C. Rothe; Alessandra Ferrario; ...
    Persistent Identifiers

    Introduction: There is continued unmet medical need for new medicines across countries especially for cancer, immunological diseases, and orphan diseases. However, there are growing challenges with funding new medicines at ever increasing prices along with funding incre...

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  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Desmond Curran; Sean Matthews; Scott D. Rowley; Jo Anne H. Young; Adriana Bastidas; Achilles Anagnostopoulos; Ibrahim Barista; Pranatharthi H. Chandrasekar; Michael Dickinson; Mohamed El Idrissi; ...
    Persistent Identifiers

    Herpes zoster (HZ) can have a substantial impact on quality of life (QoL). The vaccine efficacy (VE) of a recombinant zoster vaccine (RZV) was 68.2% (95% confidence interval [CI], 55.6% to 77.5%) in a phase 3 study in adult autologous hematopoietic stem cell transplant ...

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  • publication . Article . 2013
    Open Access English
    Authors:
    Augusto César Ferreira de Moraes; Heráclito Barbosa Carvalho; Juan Pablo Rey-López; Luis Gracia-Marco; Laurent Béghin; Anthony Kafatos; David Jiménez-Pavón; Dénes Molnár; Stefaan De Henauw; Yannis Manios; ...

    The HELENA Study takes place with the financial support of the European Community Sixth RTD Framework Programme (contract FOOD-CT-2005-007034).

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  • publication . Article . 2020
    Open Access English
    Authors:
    Laure Delavallée; Navrita Mathiah; Lauriane Cabon; Aurélien Mazeraud; Marie-Noelle Brunelle-Navas; Leticia K. Lerner; Mariana Tannoury; Alexandre Prola; Raquel Moreno-Loshuertos; Mathieu Baritaud; ...
    Persistent Identifiers
    Publisher: HAL CCSD
    Project: ANR | AIFCICD (ANR-09-BLAN-0247)

    Objectives Apoptosis-Inducing Factor (AIF) is a protein involved in mitochondrial electron transport chain assembly/stability and programmed cell death. The relevant role of this protein is underlined because mutations altering mitochondrial AIF properties result in acu...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Wu, Ona; Winzeck, Stefan; Giese, Anne-Katrin; Hancock, Brandon L.; Etherton, Mark R.; Bouts, Mark J.R.J.; Donahue, Kathleen; Schirmer, Markus D.; Irie, Robert E.; Mocking, Steven J.T.; ...
    Persistent Identifiers

    Background and Purpose- We evaluated deep learning algorithms' segmentation of acute ischemic lesions on heterogeneous multi-center clinical diffusion-weighted magnetic resonance imaging (MRI) data sets and explored the potential role of this tool for phenotyping a...

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  • publication . Article . Other literature type . 2014
    Open Access English
    Authors:
    Paul De Leyn; Christophe Dooms; Jarosław Kużdżał; Didier Lardinois; Bernward Passlick; Ramón Rami-Porta; Akif Turna; Paul Van Schil; Frederico Venuta; David A. Waller; ...

    Abstract: Accurate preoperative staging and restaging of mediastinal lymph nodes in patients with potentially resectable non-small-cell lung cancer (NSCLC) is of paramount importance. In 2007, the European Society of Thoracic Surgeons (ESTS) published an algorithm on pr...

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  • publication . Conference object . Other literature type . Preprint . Article . 2018
    Open Access English
    Authors:
    C. Abel; N. J. Ayres; G. Ban; G. Bison; K. Bodek; V. Bondar; E. Chanel; P.-J. Chiu; M. Daum; S. Emmenegger; ...
    Publisher: HAL CCSD
    Project: RCUK | Sussex Experimental Parti... (ST/N000307/1), RCUK | STFC Sussex 2015 DTP (ST/N504452/1), EC | NEDM (716651), ANR | nEDM (ANR-09-BLAN-0046)

    We report on the strategy used to optimize the sensitivity of our search for a neutron electric dipole moment at the Paul Scherrer Institute. Measurements were made upon ultracold neutrons stored within a single chamber at the heart of our apparatus. A mercury cohabitin...

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  • publication . Article . 2014
    Open Access English
    Authors:
    Cynthia J. Van Oers; Kinga Góra-Marek; Benedicte Prelot; Jerzy Datka; Vera Meynen; Pegie Cool;
    Persistent Identifiers

    Abstract: A new combination of a volumetric with a dynamic method to investigate the acidity properties of aluminosilicates is introduced. In a first step, the total acidity is determined volumetrically by the measurement of two-cycle adsorption (TCA) isotherms with amm...

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  • publication . Article . Conference object . Other literature type . 2016
    Open Access English
    Authors:
    Blanca Rodriguez; Annamaria Carusi; Najah Abi-Gerges; Rina Ariga; Oliver J. Britton; Gil Bub; Alfonso Bueno-Orovio; Rebecca A.B. Burton; Valentina Carapella; Louie Cardone-Noott; ...
    Project: WT | Safety and efficacy of an... (100246), WT | Induced pluripotent stem ... (098519)

    Both biomedical research and clinical practice rely on complex datasets for the physiological and genetic characterization of human hearts in health and disease. Given the complexity and variety of approaches and recordings, there is now growing recognition of the need ...

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  • publication . Article . 2008
    Open Access English
    Authors:
    Jerzy Gasowski; Yan Li; Tatiana Kuznetsova; Tom Richart; Lutgarde Thijs; Tomasz Grodzicki; Robert Clarke; Jan A. Staessen;
    Persistent Identifiers
    Project: EC | HYPERGENES (201550)

    BACKGROUND: The 24-h ambulatory blood pressure (ABP) is a stronger predictor of cardiovascular disease than conventional blood pressure (CBP), but it remains unclear how it compares with "usual" blood pressure (UBP), estimated after CBP has been corrected for ...

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658 research outcomes, page 1 of 66