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261 research outcomes, page 1 of 27
  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Delia Hendrie; Reza Alizadeh-Navaei; David Pereira; Tariku Jibat Beyene; Ala'a Alkerwi; Stefano Olgiati; Victoria Fan; Muktar Ahmed; Atte Meretoja; Azeem Majeed; ...
    Project: WT | Defining the population a... (095066), NIH | Stroke Investigative Rese... (3U54HG007479-03S1)

    Background: The amount of resources, particularly prepaid resources, available for health can affect access to health care and health outcomes. Although health spending tends to increase with economic development, tremendous variation exists among health financing syste...

  • publication . Article . 2015
    Open Access English
    Authors:
    Marta Labocha-Derkowska;
    Publisher: Public Library of Science (PLoS)
    Project: NIH | Quantitiative Genetic Int... (5R00HG004724-04), NIH | Caenorhabditis Genetics C... (1P40OD010440-01), NIH | Machine vision analysis o... (7R01DA018341-02)

    Fast and quantitative analysis of animal phenotypes is one of the major challenges of current biology. Here we report the WormGender open-source software, which is designed for accurate quantification of sex ratio in Caenorhabditis elegans. The software functions includ...

  • publication . Article . Other literature type . 2014
    Open Access English
    Authors:
    Traylor, Matthew; Mäkelä, Kari-Matti; Kilarski, Laura L; Holliday, Elizabeth G; Devan, William J; Nalls, Mike A; Wiggins, Kerri L; Zhao, Wei; Cheng, Yu-Ching; Achterberg, Sefanja; ...
    Publisher: PLoS genetics
    Project: EC | GEUVADIS (261123), NIH | Clotting genetic variant,... (5R01HL073410-04), NIH | MULTICENTERED STUDY OF ST... (5R01NS039987-02), NIH | Genome Wide Association C... (5U01HG004446-04), EC | ATHEROREMO (201668), NIH | Genetics Of Stroke (1Z01AG000954-02), WT | A genome wide association... (084724), NIH | Genetic Risk to Stroke in... (5U01HG004436-02), NIH | AN NCRR CENTER FOR HIGH T... (5U54RR020278-04), NIH | ISGS: The Ischemic Stroke... (5R01NS042733-02),...

    Genome-wide association studies (GWAS) have begun to identify the common genetic component to ischaemic stroke (IS). However, IS has considerable phenotypic heterogeneity. Where clinical covariates explain a large fraction of disease risk, covariate informed designs can...

  • publication . Article . Other literature type . 2014
    Open Access English
    Authors:
    Monika Rudzińska - Bar;
    Project: NIH | Dystonia Coalition (2U54NS065701-06), NIH | Identification of novel P... (5P50NS072187-04), NIH | Washington University Ins... (4UL1TR000448-10), NIH | The Role of THAP1 in Dyst... (5R01NS069936-03)

    Although coding variants in THAP1 have been causally associated with primary dystonia, the contribution of noncoding variants remains uncertain. Herein, we examine a previously identified Intron 1 variant (c.71+9C>A, rs200209986). Among 1672 subjects with mainly adult-o...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    luis ortiz; Søren Jacobsen; David D. Roberts; Angela Zivkovic; Alicia Llorente; clotilde théry; Veronika Mussack; Hernando A del Portillo Obando; Dakota Gustafson; Tom Driedonks; ...
    Project: EC | PARAGEN (708711), NIH | The Impact of Emotional S... (5F32AG047807-02), NIH | Discovering novel players... (1R56AG057430-01), NIH | Extracellular Vesicle-Med... (5R01DA040385-02), EC | VES4US (801338), EC | evFOUNDRY (801367), NIH | Novel Approaches to Captu... (1R21MH118164-01), NIH | Extracellular Vesicle and... (1R01DA047807-01)

    Ministry of Education, and grants from INCa (INCA-11548), French National Research Agency (ANR-10-IDEX-0001-02 PSL* and ANR-11-LABX-0043), SIDACTION (17-1-AAE-1138), Fondation ARC (PGA1 RF20180206962, PJA 20171206453). KWW and CT receive support from NIDA (DA040385)

  • publication . Article . Other literature type . Preprint . 2019
    Open Access English
    Authors:
    A.K. Giese; M.D. Schirmer; Vincent Thijs;
    Publisher: ELSEVIER SCI LTD
    Project: EC | ARTEMIS (753896), NIH | Quantitative MRI-based me... (5R01NS059775-05), NIH | Neuroimaging Analysis Cen... (5P41EB015902-20), NIH | Statins augment small ves... (5R01NS082285-03), NIH | MRI-GENetics Interface Ex... (5R01NS086905-03), NIH | Genetic variation in whit... (5K23NS064052-05), NIH | Data Mgmt &Analysis Core ... (5U01NS069208-02), NIH | Normobaric O2 in Ischemic... (5P50NS051343-02), NIH | Sharing canonical human s... (1R01NS063925-01)

    White matter hyperintensity (WMH) burden is a critically important cerebrovascular phenotype linked to prediction of diagnosis and prognosis of diseases, such as acute ischemic stroke (AIS). However, current approaches to its quantification on clinical MRI often rely on...

  • publication . Article . Other literature type . 2014
    Open Access
    Authors:
    Maud Heinen; Moreno-Casbas T; Moreno-Casbas MT; Carol Tishelman; Luk Bruyneel; Esther González-María; Rikard Lindqvist; Anthony Staines; Peter Griffiths; Walter Sermeus; P Anne Scott; ...
    Publisher: Wiley
    Project: EC | RN4CAST (223468), NIH | OUTCOMES OF HOSPITAL STAF... (5R01NR004513-03)

    Background\ud \ud Austerity measures and health-system redesign to minimise hospital expenditures risk adversely affecting patient outcomes. The RN4CAST study was designed to inform decision making about nursing, one of the largest components of hospital operating expen...

  • publication . Article . 2018
    Open Access English
    Authors:
    Michal Zmijewski; Martyna Elas; Martyna Sniegocka; Miroslawa Cichorek; Przemysław Płonka; Andrzej Slominski; Krystyna Urbanska; Anna Brozyna;
    Project: NIH | Role of exogenous melaton... (1R01AR056666-01A2), NIH | Significance of metabolic... (5R01AR071189-02), NIH | Mechanism of action of 20... (5R21AR066505-03)

    The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption as mechanisms o...

  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Aleksander M Grabiec; Grzegorz P. Bereta; Maja Sochalska;
    Publisher: Frontiers Media SA
    Project: NIH | Bacterial peptidylarginin... (5R01DE022597-05), EC | POLONEZ (665778)

    : BET bromodomain proteins are important epigenetic regulators of gene expression that bind acetylated histone tails and regulate the formation of acetylation-dependent chromatin complexes. BET inhibitors suppress inflammatory responses in multiple cell types and animal...

  • publication . Article . Other literature type . 2012
    Open Access English
    Authors:
    Jan J. Enghild; Ky-Anh Nguyen; Jan Potempa;
    Project: NIH | Small Molecule Imaging of... (5R01EB005011-02), NIH | BACTERIAL PROTEINASES IN ... (7R01DE009761-17), EC | GUMS AND JOINTS (261460)

    <jats:title>Abstract</jats:title> <jats:p>RgpA and Kgp gingipains are non-covalent complexes of endoprotease catalytic and hemagglutinin-adhesin domains on the surface of <jats:italic>Porphyromonas gingivalis</jats:italic>. A motif conserved in each domain has been sugg...

261 research outcomes, page 1 of 27
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