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862 research outcomes, page 1 of 87
  • publication . Article . 2014
    Open Access
    Authors:
    Anne Tscherter;
    Publisher: Elsevier BV
    Project: SNSF | Mechanisms of rhythm gene... (31003A_140754), SNSF | Emergent properties and r... (31003A_120327)

    Abstract Regeneration in the adult mammalian spinal cord is limited due to intrinsic properties of mature neurons and a hostile environment, mainly provided by central nervous system myelin and reactive astrocytes. Recent results indicate that propriospinal connections ...

  • publication . Article . Other literature type . 2010
    Open Access English
    Authors:
    Joost Woltering; denis duboule;
    Project: EC | SYSTEMSHOX.CH (232790), SNSF | Hox genes and the molecul... (310030_122008)

    In the emerging discipline of Evo-Devo, the analysis of gene expression patterns can be deceptive without a clear understanding of the underlying regulatory strategies. Here, we use the paradigm of hand and foot evolution to argue that the consideration of the regulator...

  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    Liu, Yang; Gunawan, Rudiyanto;
    Publisher: Elsevier BV
    Project: SNSF | Benchmarking, Assessment ... (200021_137614)

    The performance of model-based bioprocess optimizations depends on the accuracy of the mathematical model. However, models of bioprocesses often have large uncertainty due to the lack of model identifiability. In the presence of such uncertainty, process optimizations t...

  • publication . Other literature type . Article . 2013
    Open Access
    Authors:
    Markus Affolter; Heinz-Georg Belting;
    Publisher: Elsevier BV
    Project: SNSF | Zell Zell Interaktionen i... (310030B_138651)

    Summary Organ formation and growth requires cells to organize into properly patterned three-dimensional architectures. Network formation within the vertebrate vascular system is driven by fusion events between nascent sprouts or between sprouts and pre-existing blood ve...

  • publication . Article . Other literature type . 2010
    Open Access
    Authors:
    montenegro gouveia, susana; Michel O. Steinmetz; Linda Wordeman; Ruben Martinez-Buey;
    Project: SNSF | Mechanisms of dynamic +TI... (31003A_122545)

    SummaryThe kinesin-13 family member mitotic centromere-associated kinesin (MCAK) is a potent microtubule depolymerase [1–4]. Paradoxically, in cells it accumulates at the growing, rather than the shortening, microtubule plus ends. This plus-end tracking behavior require...

  • publication . Article . Other literature type . 2011
    Open Access
    Authors:
    Stieger, Bruno;
    Publisher: Elsevier BV
    Project: SNSF | The Role of Microdomains ... (31003A_124652)
  • publication . Article . Other literature type . 2011
    Open Access
    Authors:
    Müller Martin; Pym Edward C G; Tong Amy; Davis Graeme W;
    Publisher: Elsevier BV
    Project: SNSF | Presynaptic Mechanisms Un... (PA00P3_131508)

    Summary Homeostatic signaling systems stabilize neural function through the modulation of neurotransmitter receptor abundance, ion channel density, and presynaptic neurotransmitter release. Molecular mechanisms that drive these changes are being unveiled. In theory, mol...

  • publication . Article . Other literature type . 2015
    Open Access English
    Authors:
    Stephan Simioni; Rolf Sidler; Jürg Dual; Jürg Schweizer;
    Publisher: Published by Elsevier B.V.
    Project: SNSF | USING A BIOT-TYPE POROUS ... (PA00P2_145391)

    Avalanche control by explosives is among the key temporary preventive measures. Hitherto, little is known about wave propagation in a snowpack caused by an explosion. During the winter 2013–2014 we performed field experiments on a flat study site. We triggered slurry ex...

  • publication . Article . 2014
    Open Access English
    Authors:
    Kerstin E. Auer (Thonhauser);
    Publisher: The Authors. Published by Elsevier Ltd.
    Project: SNSF | Using experimental sexual... (PBNEP3-132801), FWF | Major Urinary Proteins: R... (P 24711), SNSF | Using experimental sexual... (PBNEP3_140190)

    Polyandry is common in many species and it has been suggested that females engage in multiple mating to increase the genetic diversity of their offspring (genetic diversity hypothesis). Multiple paternity occurs in 30% of litters in wild populations of house mice, Mus m...

  • publication . Review . Article . Other literature type . 2010
    Open Access
    Authors:
    Riekelt H. Houtkooper; Robert W. Williams;
    Project: SNSF | Phenogenomics of the sirt... (31003A_124713), EC | SIRTUINS (231138)

    Molecular and cellular networks implicated in aging depend on a multitude of proteins that collectively mount adaptive and contingent metabolic responses to environmental challenges. Here we discuss the intimate links between metabolic regulation and longevity, and outl...

862 research outcomes, page 1 of 87
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