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128,968 research outcomes, page 1 of 12,897
  • publication . Article . undefined
    Open Access English
    Authors:
    Andrews, George E.; Dixit, Atul; Yee, Ae Ja;
    Publisher: Springer Nature
  • publication . Other literature type . Article . 2016
    Open Access
    Authors:
    Watkins, Lewis M.; Neal, James W.; Loveless, Sam; Michailidou, Iliana; Ramaglia, Valeria; Rees, Mark I.; Reynolds, Richard; Robertson, Neil P.; Morgan, B. Paul; Howell, Owain W.;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    Background The symptoms of multiple sclerosis (MS) are caused by damage to myelin and nerve cells in the brain and spinal cord. Inflammation is tightly linked with neurodegeneration, and it is the accumulation of neurodegeneration that underlies increasing neurological ...

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  • publication . Article . 2011
    Open Access
    Authors:
    Igor Chikalov; Peggy Yao; Mikhail Moshkov; Jean-Claude Latombe;
    Publisher: Scientific Research Publishing, Inc.

    <p>Abstract</p> <p>Background</p> <p>Hydrogen bonds (H-bonds) play a key role in both the formation and stabilization of protein structures. They form and break while a protein deforms, for instance during the transition from a non-functional to a functional state. The ...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Verma, Rashmi; Foster, Ruth E.; Horgan, Kieran; Mounsey, Katherine; Nixon, Helen; Smalle, Natuley; Hughes, Thomas A.; Carter, Clive RD.;
    Persistent Identifiers
    Publisher: BioMed Central

    Background Approximately 30 % of breast cancer patients receive chemotherapy, yet little is known about influences of current regimens on circulating lymphocyte levels and phenotypes. Similarly, clinico-pathological factors that modify these influences, and implications...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Kelsey R. Mirkovic; Eva Lathrop; Erin Hulland; Reginald Jean-Louis; Daniel Lauture; Ghislaine Desinor D’Alexis; Endang Handzel; Reynold Grand-Pierre;
    Persistent Identifiers
    Publisher: Springer Nature

    Background Despite improvement, maternal mortality in Haiti remains high at 359/100,000 live births. Improving access to high quality antenatal and postnatal care has been shown to reduce maternal mortality and improve newborn outcomes. Little is known regarding the qua...

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  • publication . Article . 2003
    Open Access
    Authors:
    Brenda A. Jensen; Rebecca J Leeman; Jennifer J. Schlezinger; David H. Sherr;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC
    Project: NIH | Core A: Administrative Co... (5P42ES007381-17)

    <p>Abstract</p> <p>Background</p> <p>Bone marrow stromal cells produce cytokines required for the normal growth and development of all eight hematopoietic cell lineages. Aberrant cytokine production by stromal cells contributes to blood cell dyscrasias. Consequently, fa...

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  • publication . Article . 2009
    Open Access English
    Authors:
    Aaron L. Friedman;
    Persistent Identifiers
    Publisher: Springer-Verlag

    The prescription of fluid therapy in pediatrics is a common clinical event. The foundations that underpin such therapy should be understood by all clinicians involved in the short-term care of children. This article describes some important basic principles of fluid man...

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  • publication . Article . 2016
    Open Access English
    Authors:
    Stephen, Ocansey; Samuel, Kyei; Ama, Diafo; Kwabena Nkansah, Darfor; Samuel Bert, Boadi-Kusi; Peter B, Aglobitse;
    Persistent Identifiers
    Publisher: Springer Nature

    Background Glaucoma is the leading cause of irreversible blindness globally, and treatment involves considerable cost to stakeholders in healthcare. However, there is infrequent availability of cost information and patterns of management, especially in developing countr...

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  • publication . Article . 2013
    Open Access English
    Authors:
    Marion Teare; Alexandra Hayman; Munya Dimairo; Neil Shephard; Amy Whitehead; Stephen Walters;
    Persistent Identifiers
    Publisher: BioMed Central
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  • publication . Article . 2015
    Open Access
    Authors:
    Marco Del Giudice;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    Individual differences in plasticity have been classically framed as genotype-by-environment interactions, with different genotypes showing different reaction norms in response to environmental conditions. However, research has shown that early experience can be a criti...

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128,968 research outcomes, page 1 of 12,897