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1,175,194 research outcomes, page 1 of 117,520
  • publication . Article . 1985
    Open Access English
    Authors:
    M. Van Der Graaff; N. P. E. Vermeulen; Douwe D. Breimer;
    Country: Netherlands

    Abstract The metabolic clearance (CL) and half-life of racemic hexobarbitone and sleeping time were studied in rats following intra-arterial (i.a.), intraperitoneal (i.p.) and oral (p.o.) administration, at dose levels of 25 and 100 mg kg−1 of its sodium salt. CLp.o. wa...

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  • publication . Article . 2014
    Open Access
    Authors:
    Brenda A J Berendsen; Marike R C Hendriks; Kenneth Meijer; Guy Plasqui; Nicolaas C. Schaper; Hans H.C.M. Savelberg;
    Persistent Identifiers
    Country: Netherlands

    BACKGROUND: Health is associated with amount of daily physical activity. Recently, the identification of sedentary time as an independent factor, has gained interest. A valid and easy to use activity monitor is needed to objectively investigate the relationship between ...

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  • publication . Article . 2014
    Open Access English
    Authors:
    E. C. van der Linden; Richard Bintanja; Wilco Hazeleger; Caroline A. Katsman;
    Persistent Identifiers
    Country: Netherlands

    Abstract Century-scale global near-surface temperature trends in response to rising greenhouse gas concentrations in climate models vary by almost a factor of 2, with greatest intermodel spread in the Arctic region where sea ice is a key climate component. Three factors...

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  • publication . Article . 2012
    Open Access English
    Authors:
    Buganim, Yosef; Faddah, Dina A.; Cheng, Albert W.; Itskovich, Elena; Markoulaki, Styliani; Ganz, Kibibi; Klemm, Sandy L.; van Oudenaarden, Alexander; Jaenisch, Rudolf;
    Publisher: Elsevier Inc.
    Country: Netherlands
    Project: NIH | Stochastic gene expressio... (5DP1OD003936-02), NIH | In Vitro Reprogramming of... (5R37HD045022-13), NIH | Utilizing single cell app... (1F32GM099153-01A1), NIH | Organization and Infrastr... (5U54CA143874-04), NIH | GENOMIC IMPRINTING AND TH... (5R37CA084198-09)

    SummaryDuring cellular reprogramming, only a small fraction of cells become induced pluripotent stem cells (iPSCs). Previous analyses of gene expression during reprogramming were based on populations of cells, impeding single-cell level identification of reprogramming e...

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  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Cardoso, F; Bartlett, J M S; Slaets, L; van Deurzen, C H M; van Leeuwen-Stok, E; Porter, P; Linderholm, B; Hedenfalk, I; Schröder, C; Martens, J; ...
    Country: Netherlands

    Background: Male breast cancer (BC) is rare, managed by extrapolation from female BC. The International Male BC Program aims to better characterize and manage this disease. We report the results of part I, a retrospective joint analysis of cases diagnosed during a 20-ye...

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  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Bellanova, Rocco; González Fuster, Gloria;
    Countries: Belgium, Netherlands

    AbstractMaking sense of digital security practice requires grasping how data are put to use to compose the governing of individuals. Data need to be understood in their becoming, and in their becomingsomethingacross diverse practices. To do this, we suggest embracing tw...

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  • publication . Article . 2013
    Open Access English
    Authors:
    Belderok, Sanne-Meike; Rimmelzwaan, Guus F.; van den Hoek, Anneke; Sonder, Gerard J. B.;
    Persistent Identifiers
    Country: Netherlands

    textabstractTo assess the attack and incidence rates for influenza virus infections, during October 2006-October 2007 we prospectively studied 1,190 adult short-term travelers from the Netherlands to tropical and subtropical countries. Participants donated blood samples...

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  • publication . Article . 2016
    Open Access
    Authors:
    Fatima Lambarraa; Spiro E. Stefanou; Jose Maria Gil;
    Persistent Identifiers
    Countries: Spain, Spain, Netherlands

    This study addresses irreversible investment decision-making in the context of uncertainty when allowing for inefficiency to be transmitted over time. Both irreversibility and persistence in technical inefficiency can lead to sluggish adjustment of quasifixed factors of...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Zheng Y. X. Huang; Yang Yu; Frank van Langevelde; Willem F. de Boer;
    Persistent Identifiers
    Country: Netherlands

    SUMMARYThe dilution effect (DE) has been reported in many diseases, but its generality is still highly disputed. Most current criticisms of DE are related to animal diseases. Particularly, some critical studies argued that DE is less likely to occur in complex environme...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Peter R. Rijnbeek; Marten E. van den Berg; Gerard van Herpen; Henk J. Ritsema van Eck; Jan A. Kors;
    Publisher: Public Library of Science (PLoS)
    Country: Netherlands

    textabstractBackground Increased variability of beat-to-beat QT-interval durations on the electrocardiogram (ECG) has been associated with increased risk for fatal and non-fatal cardiac events. However, techniques for the measurement of QT variability (QTV) have not bee...

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1,175,194 research outcomes, page 1 of 117,520