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159,523 research outcomes, page 1 of 15,953
  • publication . Article . 2019
    Open Access English
    Authors:
    Feng Ye; Hanzhi Wang; Jia Liu; Qi Cheng; Xiaojing Chen; Huaizeng Chen;
    Persistent Identifiers
    Publisher: Nature Publishing Group UK

    Abstract Deoxyuridine 5′-triphosphate nucleotidohydrolase (dUTPase) is involved in the repair and prevention of uracil misincorporations into DNA. Maintenance of DNA integrity is critical for cancer prevention. Many studies have identified susceptibility loci and geneti...

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  • publication . Article . Conference object . 2019
    Open Access
    Authors:
    Bino Varghese; Frank Chen; Darryl Hwang; Suzanne L. Palmer; Andre Luis de Castro Abreu; Osamu Ukimura; Monish Aron; Manju Aron; Inderbir S. Gill; Vinay Duddalwar; ...
    Publisher: ACM
    Project: NIH | Big Data U: Empowering Mo... (5U24ES026465-03), NIH | Boosting the Translationa... (5R01GM114434-02)

    Abstract Multiparametric magnetic resonance imaging (mpMRI) has become increasingly important for the clinical assessment of prostate cancer (PCa), but its interpretation is generally variable due to its relatively subjective nature. Radiomics and classification methods...

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  • publication . Article . 2019
    Open Access
    Authors:
    Talalaev, Vadim; Kryzhanovskaya, Natalia; Tomm, Jens W.; Rutckaia, Viktoriia; Schilling, Joerg; Zhukov, Alexey;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    Abstract The development of a fast semiconductor laser is required for the realization of next-generation telecommunication applications. Since lasers operating on quantum dot ground state transitions exhibit only limited gain due to the saturation effect, we investigat...

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  • publication . Article . 2020
    Open Access
    Authors:
    Rosario Castro-Oropeza; Karla Vazquez-Santillan; Claudia Díaz-Gastelum; Jorge Melendez-Zajgla; Cecilia Zampedri; Eduardo Ferat-Osorio; Arturo Rodríguez-González; Lourdes Arriaga-Pizano; Vilma Maldonado;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    AbstractEpidemiological studies indicate that obesity negatively affects the progression and treatment of cervical-uterine cancer. Recent evidence shows that a subpopulation of adipose-derived stem cells can alter cancer properties. In the present project, we described ...

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  • publication . Article . 2016
    Open Access
    Authors:
    Hui-Chen Wang; Wen-Sen Lee;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    Progesterone (P4) was demonstrated to inhibit migration in vascular smooth muscle cells (VSMCs), but to enhance migration in T47D breast cancer cells. To investigate the mechanism responsible for this switch in P4 action, we examined the signaling pathway responsible fo...

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  • publication . Article . 2018
    Open Access
    Authors:
    Naoya Matsumoto; Alu Konno; Takashi Inoue; Shigetoshi Okazaki;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    Abstract In this paper, excitation light wavefront modulation is performed considering the curved sample surface shape to demonstrate high-quality deep observation using two-photon excitation microscopy (TPM) with a dry objective lens. A large spherical aberration typic...

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  • publication . Article . 2021
    Open Access
    Authors:
    Claus Peter Richter; Petrina La Faire; Xiaodong Tan; Pamela Fiebig; David M. Landsberger; Alan G. Micco;
    Persistent Identifiers
    Publisher: Springer Science and Business Media LLC

    AbstractNicolelis wrote in his 2003 review on brain-machine interfaces (BMIs) that the design of a successful BMI relies on general physiological principles describing how neuronal signals are encoded. Our study explored whether neural information exchanged between brai...

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  • publication . Article . 2017
    Open Access English
    Authors:
    Jingyun Wang; Lei Zhang; Youju Huang; Anirban Dandapat; Liwei Dai; Ganggang Zhang; Xuefei Lu; Jiawei Zhang; Weihua Lai; Tao Chen;
    Persistent Identifiers
    Publisher: Nature Publishing Group

    The probe materials play a significant role in improving the detection efficiency and sensitivity of lateral-flow immunochromatographic test strip (ICTS). Unlike conventional ICTS assay usually uses single-component, solid gold nanoparticles as labeled probes, in our pr...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Li, Wenjing; Dick, Adam; Lu, Fei; Zhang, Hui; Sun, Hong;
    Persistent Identifiers
    Publisher: Nature Publishing Group UK
    Project: NIH | Novel Regulation of Recep... (1R15NS096694-01A1), NIH | Regulation of Stem Cell P... (1R15GM131255-01)

    Abstract The proto-oncoprotein MET is a receptor tyrosine kinase that plays a key role in cancer cell growth and invasion. We have used fluorescence-tagged antibodies to activate MET in live serum-starved glioblastoma cells and monitor the fate of antibody-bound MET rec...

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  • publication . Article . 2019
    Open Access English
    Authors:
    Bashir, Khalid; Kappala, Deepthi; Singh, Yogendra; Dar, Javeed Ahmad; Mariappan, Asok Kumar; Kumar, Ajay; Krishnaswamy, Narayanan; Dey, Sohini; Chellappa, Madhan Mohan; Goswami, Tapas Kumar; ...
    Persistent Identifiers
    Publisher: Nature Publishing Group UK

    Abstract Live intermediate plus infectious bursal disease virus (IBDV) vaccines (hot vaccines) are used for protection against the virulent IBDV strains in young chickens. We evaluated the potential of Toll-like receptor (TLR) agonists to alleviate hot vaccine-induced i...

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159,523 research outcomes, page 1 of 15,953