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1,699 research outcomes, page 1 of 170
  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Jessica Julia Falk; Martina Winkelmann; Kerstin Laib Sampaio; Caroline Paal; Hubert Schrezenmeier; Mira Alt; Richard J. Stanton; Adalbert Krawczyk; Ramin Lotfi; Christian Sinzger;
    Persistent Identifiers
    Publisher: MDPI AG

    Immunoglobulins are only moderately effective for the treatment of human cytomegalovirus\ud (HCMV) infections, possibly due to ineffectiveness against cell-associated virus spread. To overcome\ud this limitation, we aimed to identify individuals with exceptional antibod...

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  • publication . Article . Other literature type . 2010
    Open Access English
    Authors:
    Richard J. Stanton; Katarina Baluchova; Derrick J. Dargan; Charles Cunningham; Orla Sheehy; Sepehr Seirafian; Brian P. McSharry; M. Lynne Neale; James A. Davies; Peter Tomasec; ...
    Publisher: American Society for Clinical Investigation

    Human cytomegalovirus (HCMV) in clinical material cannot replicate efficiently in vitro until it has adapted by mutation. Consequently, wild-type HCMV differ fundamentally from the passaged strains used for research. To generate a genetically intact source of HCMV, we c...

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  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    Barend H. J. de Graaf; Walter Dewitte;
    Persistent Identifiers
    Publisher: Wiley

    Fertilisation is the result of successful fusion of female and male gametes, forming a zygote that develops into the embryo. From the perspective of cell cycle control, fertilisation is a hat‐trick. Firstly, the generation of gametes depends on the generation of haploid...

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  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Poniecka, Ewa; Bagshaw, Elizabeth; Martyn, Tranter; Sass, Henrik; Christopher, Williamson; Alexandre, Anesio; Team, Black and Bloom;
    Publisher: Taylor & Francis

    Microorganisms play a significant role in changing the physical properties of the surface of the Greenland Ice Sheet. Cryoconite holes are a hotspot for this microbial activity, yet little is known about the REDOX conditions that develop within them. In this study, we u...

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  • publication . Article . Review . Other literature type . 2017
    Open Access English
    Authors:
    Nurmatov,; Sheikh,; Akdis,; Eigenmann,; Sampson,; Papadopoulos,; O'Mahony,; Poulsen,; Santos,; Roberts,; ...
    Project: EC | BM4SIT (601763)

    BACKGROUND:The European Academy of Allergy and Clinical Immunology (EAACI) is developing Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated Food Allergy. To inform the development of clinical recommendations, we sought to critically assess evidence on the effe...

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  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Ilaria Muller; Carla Moran; Beatriz Lecumberri; Brigitte Decallonne; Neil Robertson; Joanne L. Jones; Colin M. Dayan;
    Publisher: S. Karger AG

    Thyroid dysfunction (TD) frequently occurs as an autoimmune complication of immune reconstitution therapy (IRT), especially in individuals with multiple sclerosis treated with alemtuzumab, a pan-lymphocyte depleting drug with subsequent recovery of immune cell numbers. ...

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  • publication . Other literature type . Article . 2017 . Embargo End Date: 05 May 2017
    Open Access
    Authors:
    Jessica F. Stephenson; Kyle A. Young; Jordan Fox; Jukka Jokela; Joanne Cable; Sarah E. Perkins;
    Publisher: Royal Society Publishing

    Infectious disease dynamics depend on the speed, number and fitness of parasites transmitting from infected hosts (‘donors’) to parasite-naive ‘recipients’. Donor heterogeneity likely affects these three parameters, and may arise from variation between donors in traits...

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  • publication . Article . Other literature type . 2011
    Open Access English
    Authors:
    Marie-Alexandrine Sicre; Ian Hall; Juliette Mignot; Myriam Khodri; Ullah Ezat; Minh-Xuan Truong; Jón Eiríksson; Karen Luise Knudsen;
    Persistent Identifiers
    Publisher: American Geophysical Union
    Project: EC | THOR (212643)

    International audience; A decadal resolution time series of sea surface temperature (SST) spanning the last two millennia is reconstructed by combining a proxy record from a new sediment sequence with previously published data from core MD99-2275, north of Iceland. The ...

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  • publication . Other literature type . Article . Review . 2017
    Open Access English
    Authors:
    Nurmatov, Ulugbek; Dhami, Sangeeta; Arasi, Stefania; Roberts, Graham; Pfaar, Oliver; Muraro, Antonella; Ansotegui, Ignacio J.; Calderon, Moises; Cingi, Cemal; Durham, Stephen; ...

    Background The European Academy of Allergy and Clinical Immunology (EAACI) is developing Guidelines on Allergen Immunotherapy (AIT) for Allergic Rhinoconjunctivitis (ARC). To inform the development of recommendations, we sought to critically assess the systematic review...

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  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Florian A. Twaroch; Paul Brindley; Paul Clough; Christopher B. Jones; Robert C. Pasley; Sue Mansbridge;
    Publisher: Taylor & Francis

    People often communicate with reference to informally agreed places, such as ‘the city centre’. However, views of the spatial extent of such areas may vary and result in imprecise regions. We compare perceptions of Sheffield’s City Centre from a street survey (with 61 p...

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1,699 research outcomes, page 1 of 170