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166,902 research outcomes, page 1 of 16,691
  • publication . Other literature type . Article . 2014
    Open Access
    Authors:
    Yasuko Osakada;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | Engineering external forc... (1DP2NS082125-01), NSF | CAREER: Nanopillar Electr... (1055112)

    Intracellular recording of action potentials is important to understand electrically-excitable cells. Recently, vertical nanoelectrodes have been developed to achieve highly sensitive, minimally invasive, and large scale intracellular recording. It has been demonstrated...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Jozef Dingemans; Bandita Poudyal; Holger Sondermann; Karin Sauer;
    Publisher: American Society for Microbiology
    Project: NIH | Role of SagS signaling an... (1R21AI119726-01), NIH | Molecular mechanism regul... (3R01GM123609-07S1), NIH | Role of PA4878 in biofilm... (5R01AI080710-08)

    The membrane-bound sensory protein SagS plays a pivotal role in P. aeruginosa biofilm formation and biofilm cells gaining their heightened resistance to antimicrobial agents, with SagS being the control point at which both pathways diverge. Here, we demonstrate for the ...

  • publication . Other literature type . Article . 2013
    Open Access
    Authors:
    Randy Stockbridge; Janice Robertson;
    Publisher: eLife Sciences Publications, Ltd
    Project: NIH | Reversible dimerization o... (5K99GM101016-02), NIH | Asymmetric flow FFF and C... (1S10RR023748-01)

    Fluoride ion, ubiquitous in soil, water, and marine environments, is a chronic threat to microorganisms. Many prokaryotes, archea, unicellular eukaryotes, and plants use a recently discovered family of F− exporter proteins to lower cytoplasmic F− levels to counteract th...

  • publication . Other literature type . Article . 2018
    Open Access
    Authors:
    Cai, Yuan; Ford, Christopher P.;
    Publisher: Elsevier BV
    Project: NIH | Validating and extending ... (1UF1NS107710-01), NIH | Encoding dopamine signals... (5R01DA035821-03), NIH | Regulation of striatal ac... (5R01NS095809-02)

    SUMMARY The balance of dopamine and acetylcholine in the dorsal striatum is critical for motor and learning functions. Midbrain dopamine cells and local cholinergic interneurons (ChIs) densely innervate the striatum and have strong reciprocal actions on each other. Alth...

  • publication . Article . 2020
    Open Access English
    Authors:
    Leslie R. Morse; Nguyen Nguyen; Yan Xu; Prakash Jha; Ricardo A. Battaglino;
    Publisher: BioMed Central
    Project: NIH | Adiposity and Bone Loss i... (1R01AR059270-01)

    Abstract Background Peroxiredoxin activated in M-CSF stimulated monocytes (PAMM) is a novel protein produced by adipocytes with putative redox regulatory and anti-inflammatory properties. Because acute spinal cord injury (SCI) is associated with oxidative stress and neu...

  • publication . Article . Other literature type . 2016
    Open Access
    Authors:
    Megan Roberts;
    Publisher: Dove Medical Press Ltd.
    Project: NIH | LINEBERGER CANCER CONTROL... (1R25CA057726-01), NIH | UNC BIRCWH Career Develop... (5K12HD001441-12), NIH | Pilot Project (1U54CA153602-01)

    PURPOSE: Adjuvant endocrine therapy (ET) can reduce the risk of recurrence among females with hormone receptor-positive breast cancer. Overall, initiation and adherence to ET are suboptimal, though reasons are not well described. The study's objective was to better unde...

  • publication . Article . Other literature type . 2017
    Open Access
    Authors:
    FUGUI ZHANG; Zongyue Zeng;
    Publisher: Wiley
    Project: NIH | Re-Engineering Translatio... (2UL1TR000430-06), NIH | Differential Effects of B... (5K08DE020140-03), NIH | Center for Herbal Researc... (5P01AT004418-02)

    Abstract The cranial suture complex is a heterogeneous tissue consisting of osteogenic progenitor cells and mesenchymal stem cells (MSCs) from bone marrow and suture mesenchyme. The fusion of cranial sutures is a highly coordinated and tightly regulated process during d...

  • publication . Article . 2015
    Open Access English
    Authors:
    Ashlee Earl;
    Publisher: Springer Nature
    Project: NIH | Defining the Human Microb... (3U54HG004969-04S1), NIH | Construction of A Referen... (5U54AI084844-02), NIH | Cultivating the uncultiva... (5R21DE018026-02), NIH | Cultivation and domestica... (1RC1DE020707-01)

    Here we report a summary classification and the features of five anaerobic oral bacteria from the family Peptostreptococcaceae. Bacterial strains were isolated from human subgingival plaque. Strains ACC19a, CM2, CM5, and OBRC8 represent the first known cultivable member...

  • publication . Article . 2016
    Open Access English
    Authors:
    Il-Young Kim; Sang-Hoon Suh; In-Kyu Lee; Robert R Wolfe;
    Publisher: Nature Publishing Group
    Project: NIH | Arkansas Center for Clini... (8UL1TR000039-04), NIH | Arkansas Center for Clini... (5KL2TR000063-05)

    The human body is in a constant state of turnover, that is, being synthesized, broken down and/or converted to different compounds. The dynamic nature of in vivo kinetics of human metabolism at rest and in stressed conditions such as exercise and pathophysiological cond...

  • publication . Part of book or chapter of book . 2011
    Open Access English
    Authors:
    Joerg Kumbrink; Kathrin H.;
    Publisher: InTech
    Project: NIH | Lysyl Oxidase Propeptide:... (5R01CA143108-04)

    Frequently, breast cancer is treated before and after surgery with chemotherapy, hormone, and radiation therapies. However, breast cancers can evolve and stop responding to chemotherapeutic drugs, including adriamycin (doxorubicin), and hormone therapy with tamoxifen. A...

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