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3 research outcomes, page 1 of 1
  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Rachael Natrajan; Salvatore Piscuoglio; Charlotte K Y Ng;
    Publisher: Nature Publishing Group UK
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), SNSF | The landscape of long non... (PZ00P3_168165)

    Metaplastic breast cancer (MBC) is a rare special histologic type of triple-negative breast cancer, characterized by the presence of neoplastic cells showing differentiation towards squamous epithelium and/or mesenchymal elements. Here we sought to define whether histol...

  • publication . Preprint . 2020
    Open Access English
    Authors:
    Joanna Cyrta; Anke Augspach; Maria Rosaria de Filippo; Davide Prandi; Phillip Thienger; Matteo Benelli; Victoria Cooley; Rohan Bareja; David Wilkes; Sung-Suk Chae; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: EC | SPICE (648670), NIH | Collaborative genomic alt... (1R01CA233650-01), NIH | Towards Understanding Pro... (5R01CA125612-04), SNSF | The landscape of long non... (PZ00P3_168165), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | RATIONAL DESIGN OF PROSTA... (5P50CA092629-10)

    <jats:title>Abstract</jats:title><jats:p>Advanced prostate cancer initially responds to hormonal treatment, but ultimately becomes resistant and requires more potent therapies. One mechanism of resistance observed in ∼10% of these patients is through lineage plasticity,...

  • publication . Article . Other literature type . Preprint . 2018
    Open Access
    Authors:
    Christos Hatzis; Salvatore Piscuoglio; Charlotte K Y Ng;
    Publisher: Elsevier BV
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), SNSF | The landscape of long non... (PZ00P3_168165)

    SUMMARY Multi-region sequencing is used to detect intratumor genetic heterogeneity (ITGH) in tumors. To assess whether genuine ITGH can be distinguished from sequencing artifacts, we performed whole-exome sequencing (WES) on three anatomically distinct regions of the sa...

3 research outcomes, page 1 of 1
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