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  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    S Ken Tian; Richard J. Wong; Diego Chowell; Ian Ganly; Justin Tepe; Marc Cohen; Luc G. T. Morris; Ronald Ghossein; Leonard H. Wexler; Zaineb Nadeem; ...
    Publisher: Springer Science and Business Media LLC
    Project: NIH | Functionalizing recurrent... (1K08DE024774-01), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Elucidating genetics of r... (1R01CA205426-01A1), NIH | Towards Precision Immuno-... (1R35CA232097-01), NIH | Identifying and targeting... (1R01DE027738-01)

    Anti-tumor immunity is driven by self vs. non-self discrimination. Many immunotherapeutic approaches to cancer have taken advantage of tumor neoantigens derived from somatic mutations. Here, we demonstrate that gene fusions are a source of immunogenic neoantigens that c...

1 research outcomes, page 1 of 1