Variations in hematoxylin and eosin (H&E) stained images (due to clinical lab protocols, scanners, etc) directly impact the quality and accuracy of clinical diagnosis, and hence it is important to control for these variations for a reliable diagnosis. In this work, we p...

<jats:title>Abstract</jats:title><jats:p>The remarkable growth of multi-platform genomic profiles has led to the multiomics data integration challenge. The effective integration of such data provides a comprehensive view of the molecular complexity of cancer tumors and ...

<jats:title>Abstract</jats:title><jats:p>The study of large-scale pharmacogenomics provides an unprecedented opportunity to develop computational models that can accurately predict large cohorts of cell lines and drugs. In this work, we present a novel method for predic...

Author(s): Taghvaei, Amirhossein; Georgiou, Tryphon T; Norton, Larry; Tannenbaum, Allen R | Abstract: The purpose of this work is to make a case for epidemiological models with fractional exponent in the contribution of sub-populations to the transmission rate. More spe...

Although brain functionality is often remarkably robust to lesions and other insults, it may be fragile when these take place in specific locations. Previous attempts to quantify robustness and fragility sought to understand how the functional connectivity of brain netw...

Unbalanced optimal mass transport (OMT) seeks to remove the conservation of mass constraint by adding a source term to the standard continuity equation in the Benamou-Brenier formulation of OMT. In this study, we show how the unbalanced case fits into the vector-valued ...

<jats:title>Abstract</jats:title> <jats:p>Many biological datasets are high-dimensional yet manifest an underlying order. In this paper, we describe an unsupervised data analysis methodology that operates in the setting of a multivariate dataset and a network which expr...

<jats:title>Abstract</jats:title><jats:p>The emerging field of radiomics, which consists of transforming standard-of-care images to quantifiable scalar statistics, endeavors to reveal the information hidden in these macroscopic images. This field of research has found d...

Comment: 6 pages, 6 figures

<jats:title>Abstract</jats:title><jats:p>Current state-of-the-art models for estimating the pharmacokinetic parameters do not account for intervoxel movement of the contrast agent (CA). We introduce an optimal mass transport (OMT) formulation that naturally handles inte...