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8 research outcomes, page 1 of 1
  • publication . Article . 2017
    Open Access English
    Authors:
    Brand, Christian; Iacono, Pasquale; Pérez‐Medina, Carlos; Mulder, Willem J. M.; Kircher, Moritz F.; Reiner, Thomas;
    Publisher: John Wiley and Sons Inc.
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MRI-Photoacoustic-Raman N... (1R01EB017748-01A1)

    Abstract Here, we report a method to specifically bind liposomal radiopharmaceuticals to a CoCrMo alloy, which can be used in arterial stents, via an irreversible inverse electron‐demand Diels–Alder reaction. Inspired by recent accomplishments in pre‐targeted imaging us...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Stefan Harmsen;
    Publisher: Ivyspring International Publisher
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | The Ivis Spectrum CT for ... (1S10OD016207-01), NIH | MRI-Photoacoustic-Raman N... (1R01EB017748-01A1), NSF | IGERT: Returning the Radi... (0965983)

    : A single contrast agent that offers whole-body non-invasive imaging along with the superior sensitivity and spatial resolution of surface-enhanced resonance Raman scattering (SERRS) imaging would allow both pre-operative mapping and intraoperative imaging and thus be ...

  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    Sheryl Roberts; Arianna Strome; Crystal Choi; Chrysafis Andreou; Susanne Kossatz; Christian Brand; Travis Williams; Michelle Bradbury; Moritz F. Kircher; Yana K. Reshetnyak; ...
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Development of Nuclear Au... (5R21CA191679-02), NIH | Ultrabright Theranostic S... (5R01CA222836-02), NIH | Mechanism and Uses of Tra... (5R01GM073857-07), NIH | Radioiodinated Multifunct... (1R01CA204441-01A1), NIH | MRI-Photoacoustic-Raman N... (1R01EB017748-01A1)

    Abstract Breast cancer is the most common type of malignant growth in women. Early detection of breast cancer, as well as the identification of possible metastatic spread poses a significant challenge because of the structural and genetic heterogeneity that occurs durin...

  • publication . Article . 2019
    Open Access English
    Authors:
    Fay Nicolson; Bohdan Andreiuk; Chrysafis Andreou; Hsiao-Ting Hsu; Scott Rudder; Moritz F. Kircher;
    Publisher: Ivyspring International Publisher
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Ultrabright Theranostic S... (5R01CA222836-02), NIH | MRI-Photoacoustic-Raman N... (1R01EB017748-01A1)

    : Rationale: The goal of imaging tumors at depth with high sensitivity and specificity represents a significant challenge in the field of biomedical optical imaging. 'Surface enhanced Raman scattering' (SERS) nanoparticles (NPs) have been employed as image contrast agen...

  • publication . Article . 2018
    Open Access English
    Authors:
    Roberts, Sheryl; Andreou, Chrysafis; Choi, Crystal; Donabedian, Patrick; Jayaraman, Madhumitha; Pratt, Edwin C.; Tang, Jun; Pérez-Medina, Carlos; Jason de la Cruz, M.; Mulder, Willem J. M.; ...
    Publisher: Royal Society of Chemistry
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Development of Nuclear Au... (5R21CA191679-02), NIH | Exploring PSMA Biology in... (1R01CA212379-01A1), NIH | PET/MRI to study nanother... (1R01HL125703-01), NIH | MRI-Photoacoustic-Raman N... (1R01EB017748-01A1), NIH | Radioiodinated Multifunct... (1R01CA204441-01A1)

    Optoacoustic imaging offers the promise of high spatial resolution and, at the same time, penetration depths well beyond the conventional optical imaging technologies, advantages that would be favorable for a variety of clinical applications. However, similar to optical...

  • publication . Other literature type . Article . 2014
    Open Access
    Authors:
    Kenneth Pitter;
    Publisher: American Chemical Society (ACS)
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Molecular Imaging: Traini... (1R25CA096945-01), NIH | MRI-Photoacoustic-Raman N... (1R01EB017748-01A1)

    The current difficulty in visualizing the true extent of malignant brain tumors during surgical resection represents one of the major reasons for the poor prognosis of brain tumor patients. Here, we evaluated the ability of a hand-held Raman scanner, guided by surface-e...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Jonathan Coleman; Jaya Prakash;
    Publisher: Ivyspring International Publisher
    Project: EC | BERTI (605162), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MRI-Photoacoustic-Raman N... (1R01EB017748-01A1)

    Objective: Monitoring emerging vascular-targeted photodynamic therapy (VTP) and understanding the time-dynamics of treatment effects remains challenging. We interrogated whether handheld multispectral optoacoustic tomography (MSOT) could noninvasively monitor the effect...

  • publication . Article . Other literature type . 2015
    Open Access English
    Authors:
    Stefan Harmsen; Charles Michael Drain;
    Publisher: American Chemical Society
    Project: NIH | The Ivis Spectrum CT for ... (1S10OD016207-01), NIH | Combined Pre & Intraopera... (4K08CA163961-05), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Cerenkov-emission based n... (5R01EB014944-04), NSF | IGERT: Returning the Radi... (0965983), NIH | MRI-Photoacoustic-Raman N... (1R01EB017748-01A1), NIH | Cerenkov luminescence ima... (5R01CA183953-04)

    Chelator-free nanoparticles for intrinsic radiolabeling are highly desirable for whole-body imaging and therapeutic applications. Several reports have successfully demonstrated the principle of intrinsic radiolabeling. However, the work done to date has suffered from mu...

8 research outcomes, page 1 of 1
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