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  • publication . Article . 2020
    Open Access English
    Ball, Daniel P; Taabazuing, Cornelius Y; Griswold, Andrew R; Orth, Elizabeth L; Rao, Sahana D; Kotliar, Ilana B; Vostal, Lauren E; Johnson, Darren C; Bachovchin, Daniel A;
    Publisher: Life Science Alliance LLC
    Project: NIH | Weill Cornell/Rockefeller... (5T32GM007739-30), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Tri-Institutional PhD Pro... (1T32GM115327-01), NIH | Characterizing the Mechan... (1R01AI137168-01)

    Pathogen-related signals induce a number of cytosolic pattern-recognition receptors (PRRs) to form canonical inflammasomes, which activate pro-caspase-1 and trigger pyroptotic cell death. All well-studied inflammasome-forming PRRs oligomerize with the adapter protein AS...

1 research outcomes, page 1 of 1