Advanced search
Filters (4 )
Filters
Clear All
PublicationsOpen AccessMOUSE GENETICSNE-CAT Center for Advanced Macromo...Structural and Biochemical Charact...
Download Results
1 research outcomes, page 1 of 1
  • publication . Article . 2017
    Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase.
    Open Access
    Authors:
    John C. Zinder; Mom Das; Christopher D. Lima; Elizabeth V. Wasmuth; Dimitrios Zattas;
    doi: 10.7554/elife.29062
    Publisher: eLife Sciences Publications, Ltd
    Project: NIH | MOLECULAR GENETIC ANALYSI... (5F32GM012006-03), NIH | Structural and Biochemica... (5F31GM097910-02), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Structural studies of RNA... (1R35GM118080-01), NIH | Structural and Functional... (5R01GM079196-07), NIH | NE-CAT Center for Advance... (4P41GM103403-14), NIH | Pixel Array Detector for ... (1S10RR029205-01)

    Nuclear RNA exosomes catalyze a range of RNA processing and decay activities that are coordinated in part by cofactors, including Mpp6, Rrp47, and the Mtr4 RNA helicase. Mpp6 interacts with the nine-subunit exosome core, while Rrp47 stabilizes the exoribonuclease Rrp6 a...

1 research outcomes, page 1 of 1