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PublicationsOpen AccessMOUSE GENETICSVACCINIA VIRUS MRNA TRANSCRIPTION ...NE-CAT Center for Advanced Macromo...
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  • publication . Article . 2017
    Structural basis for the GTP specificity of the RNA kinase domain of fungal tRNA ligase.
    Open Access English
    Authors:
    Yehuda Goldgur; Barbara S. Remus; Stewart Shuman;
    doi: 10.1093/nar/gkx1159
    pmc: PMC5728400
    pmid: 29165709
    Publisher: Oxford University Press
    Project: NIH | VACCINIA VIRUS MRNA TRANS... (2R01GM042498-10), NIH | Pixel Array Detector for ... (1S10RR029205-01), NIH | NE-CAT Center for Advance... (4P41GM103403-14), NIH | MOUSE GENETICS (2P30CA008748-43)

    Abstract Fungal tRNA ligase (Trl1) is an essential enzyme that repairs RNA breaks with 2′,3′-cyclic-PO4 and 5′-OH ends inflicted during tRNA splicing and non-canonical mRNA splicing in the fungal unfolded protein response. Trl1 is composed of C-terminal cyclic phosphodi...

1 research outcomes, page 1 of 1