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  • publication . Other literature type . Article . Preprint . 2018
    Structures reveal opening of the store-operated calcium channel Orai
    Open Access
    Authors:
    Xiaowei Hou; Stephen B. Long; Shana R. Burstein;
    doi: 10.7554/elife.36758 , 10.1101/284034 , 10.1016/j.bpj.2018.11.1637
    Publisher: eLife Sciences Publications, Ltd
    Project: NIH | MOLECULAR GENETIC ANALYSI... (5F32GM012006-03), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | 3D Structure and Function... (2R01GM094273-06), NIH | Pixel Array Detector for ... (1S10RR029205-01), NIH | NE-CAT Center for Advance... (4P41GM103403-14)

    <jats:title>Abstract</jats:title><jats:p>The store-operated calcium (Ca<jats:sup>2+</jats:sup>) channel Orai governs Ca<jats:sup>2+</jats:sup> influx through the plasma membrane of many non-excitable cells in metazoans. The channel opens in response to depletion of Ca<j...

1 research outcomes, page 1 of 1