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6 research outcomes, page 1 of 1
  • publication . Preprint . Other literature type . 2019
    Open Access
    Authors:
    Schluter, Jonas; Peled, Jonathan U.; Taylor, Bradford P.; Smith, Melody; Markey, Kate A.; Taur, Ying; Niehus, Rene; Staffas, Anna; Dai, Anqi; Fontana, Emily; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | Systems Biology of Microb... (5U01AI124275-03), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Mathematical ecology mode... (1R01AI137269-01A1)

    ABSTRACT The gut microbiota influences the development and homeostasis of the mammalian immune system 1–3 , can alter immune cell compositions in mice 4–7 , and is associated with responses to immunotherapy that rely on the activity of peripheral immune cells 8–12 . Sti...

  • publication . Preprint . Article . Other literature type . 2019
    Open Access
    Authors:
    Morjaria, Sejal; Schluter, Jonas; Taylor, Bradford P.; Littmann, Eric R.; Carter, Rebecca A.; Fontana, Emily; Peled, Jonathan U.; van den Brink, Marcel R.M.; Xavier, Joao B.; Taur, Ying;
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Systems Biology of Microb... (5U01AI124275-03), NIH | MARROW TRANSPLANTATION IN... (5P01CA023766-14), NIH | Endothelial cells regulat... (1R01CA228358-01)

    Dramatic microbiota changes and loss of commensal anaerobic bacteria are associated with adverse outcomes in hematopoietic cell transplantation (HCT) recipients. In this study, we demonstrate these dynamic changes at high resolution through daily stool sampling and asse...

  • publication . Article . Other literature type . 2019
    Open Access English
    Authors:
    Keith, James W.; Pamer, Eric G.;
    Publisher: Rockefeller University Press
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Innate Immune Defense aga... (5R01AI095706-03), NIH | Systems Biology of Microb... (5U01AI124275-03), NIH | MARROW TRANSPLANTATION IN... (5P01CA023766-14), NIH | TNF Mediated Immune Defen... (5R01AI042135-09)

    The emergence of antibiotic-resistant bacterial pathogens is an all-too-common consequence of antibiotic use. Although antibiotic resistance among virulent bacterial pathogens is a growing concern, the highest levels of antibiotic resistance occur among less pathogenic ...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Becattini, Simone; Littmann, Eric R.; Carter, Rebecca A.; Kim, Sohn G.; Morjaria, Sejal M.; Ling, Lilan; Gyaltshen, Yangtsho; Fontana, Emily; Taur, Ying; Leiner, Ingrid M.; ...
    Publisher: The Rockefeller University Press
    Project: NIH | Effects of the Intestinal... (5K23AI095398-05), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | TNF Mediated Immune Defen... (5R01AI042135-09), NIH | Systems Biology of Microb... (5U01AI124275-03)

    Becattini et al. provide evidence that a diverse gut microbiota antagonizes the foodborne pathogen Listeria monocytogenes in the intestinal lumen, thereby reducing bloodstream invasion. Microbiota perturbation by antibiotic treatment increases susceptibility to listerio...

  • publication . Other literature type . Preprint . 2019
    Open Access
    Authors:
    Sejal Morjaria; Allen W. Zhang; Sohn Kim; Jonathan U. Peled; Simone Becattini; Eric R. Littmann; Eric. G. Pamer; Miguel-Angel Perales; Michael C. Abt;
    Publisher: bioRxiv
    Project: NIH | Systems Biology of Microb... (5U01AI124275-03), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MARROW TRANSPLANTATION IN... (5P01CA023766-14), NIH | Endothelial cells regulat... (1R01CA228358-01), NIH | Immune-Microbiota Interac... (4R00AI125786-03), NIH | Mathematical ecology mode... (1R01AI137269-01A1)

    <jats:title>Background</jats:title><jats:p>Monocytes are an essential cellular component of the innate immune system that support the host’s effectivenss to combat a range of infectious pathogens. Hemopoietic cell transplantation (HCT) results in transient monocyte depl...

  • publication . Article . Other literature type . 2019
    Open Access
    Authors:
    Matthew T. Sorbara; Krista Dubin; Eric R. Littmann; Thomas U. Moody; Emily Fontana; Ruth Seok; Ingrid M. Leiner; Ying Taur; Jonathan U. Peled; Marcel R.M. van den Brink; ...
    Publisher: Rockefeller University Press
    Project: NIH | Innate Immune Defense aga... (5R01AI095706-03), NIH | Systems Biology of Microb... (5U01AI124275-03), NIH | TNF Mediated Immune Defen... (5R01AI042135-09), NIH | MOUSE GENETICS (2P30CA008748-43), CIHR

    Klebsiella pneumoniae, Escherichia coli, and other members of the Enterobacteriaceae family are common human pathogens that have acquired broad antibiotic resistance, rendering infection by some strains virtually untreatable. Enterobacteriaceae are intestinal residents,...

6 research outcomes, page 1 of 1
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