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  • publication . Other literature type . Article . 2017
    Open Access
    Authors:
    Scott A. Armstrong; Scott A. Armstrong; Eric Still; Richard Koche; Alex Kentsis; Alex Kentsis; Anton G. Henssen; Anton G. Henssen; Elias Rodriguez-Fos; Ian C. MacArthur; ...
    Publisher: Springer Science and Business Media LLC
    Project: NIH | Administrative Core (5P50CA140146-04), NIH | Aberrant activation of HG... (5K08CA160660-02), NIH | MSKCC Pilot Center for Pr... (5U54OD020355-04), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Clinical and Translationa... (3UL1TR000457-08S1), WT

    Genomic rearrangements are a hallmark of human cancers. Here, we identify the piggyBac transposable element derived 5 (PGBD5) gene as encoding an active DNA transposase expressed in the majority of childhood solid tumors, including lethal rhabdoid tumors. Using assembly...

1 research outcomes, page 1 of 1