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12 research outcomes, page 1 of 2
  • publication . Article . Preprint . Other literature type . 2019
    Open Access English
    Authors:
    Jiang, Xia; Finucane, Hilary K; Schumacher, Fredrick R; Schmit, Stephanie L; Tyrer, Jonathan; Han, Younghun; Michailidou, Kyriaki; Lesseur, Corina; Kuchenbaecker, Karoline B; Dennis, Joe; ...
    Publisher: Nature Publishing Group
    Project: NIH | The Vanderbilt Institute ... (6UL1TR000445-11), NIH | Discovery and verificatio... (5R01CA189184-04), NHMRC | Markers of androgen actio... (450104), NIH | The Mitochondrial Genome ... (5R01CA149429-05), NIH | Cancer Risk Reduction and... (2R37CA070867-12), NIH | Genes contributing for ni... (5R01DA017932-07), NIH | Consortium Study to Ident... (5R01CA148667-05), NIH | Career Development (Ingle... (5P50CA116201-08), NIH | Breast &prostate cancer &... (1U01CA098216-01), NIH | Characterizing Genetic Su... (5U01CA098710-06),...

    Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association study summary statistics across six cancer types based on a total of 296,215 cases and 301,319 controls of Europ...

  • publication . Article . 2013
    Open Access English
    Authors:
    Jolanta Lissowska; Carlotta Sacerdote; Fredrick Schumacher; Christine Friedenreich; Sara Olson; Veronica Setiawan; Jirong Long; Marta Crous-Bou; Amanda Spurdle; Alison Margaret Dunning; ...
    Publisher: Springer Berlin Heidelberg
    Project: NIH | Epidemiology of Ovarian C... (5R01CA087538-02), NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Molecular Epidemiology of... (1R01CA105212-01A1), NIH | CALIFORNIA TEACHERS STUDY (5R01CA077398-09), NIH | Genome-Wide Association S... (5R01CA134958-02), NIH | GENES AND THE ESTROGEN EF... (1R01CA091019-01A1), NIH | GENETIC SUSCEPTIBILITY TO... (5R01CA082838-04), NIH | MOLECULAR EPIDEMIOLOGIC S... (1R01CA090899-01), NHMRC | Molecular Epidemiology of... (339435),...

    Endometrial cancer (EC), a neoplasm of the uterine epithelial lining, is the most common gynecological malignancy in developed countries and the fourth most common cancer among US women. Women with a family history of EC have an increased risk for the disease, suggestin...

  • publication . Article . 2015
    Open Access English
    Authors:
    Jolanta Lissowska; Carlotta Sacerdote; FULVIO RICCERI; Christine Friedenreich; Sara Olson; Veronica Setiawan; Amanda Spurdle; Anne Zeleniuch-Jacquotte; Elisabete Weiderpass;
    Publisher: Nature Publishing Group
    Project: NIH | GENETIC SUSCEPTIBILITY TO... (5R01CA082838-04), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | SURVEILLANCE, EPIDEMIOLOG... (N01CN067001-000), NIH | Vitamin D, Related Genes ... (2R01CA098661-06A2), NIH | Soyfood, gene polymorphis... (5R01CA092585-05), NIH | EPIDEMIOLOGIC STUDIES OF ... (5P01CA033619-05), NIH | DISTRIBUTION OF BODY FAT ... (3R01CA039742-11S1), NIH | Experimental Pathology (5P30CA016087-32), NIH | COLLABORATIVE STUDY OF OV... (5R01CA058598-05), NIH | CASE-CONTROL STUDY OF POS... (5R01CA048774-04),...

    Background: Nulliparity is an endometrial cancer risk factor, but whether or not this association is due to infertility is unclear. Although there are many underlying infertility causes, few studies have assessed risk relations by specific causes. Methods: We conducted ...

  • publication . Article . 2016
    Open Access
    Authors:
    Permuth, J. B.; Reid, B.; Earp, M.; Chen, Y. A.; Monteiro, A. N. A.; Chen, Z.; Chenevix-Trench, G.; Fasching, P. A.; Beckmann, M. W.; Lambrechts, D.; ...
    Project: NIH | Epidemiology of Ovarian C... (5R01CA087538-02), NIH | Premenopausal Hormone Lev... (5R01CA067262-08), NIH | MOUSE GENETICS (2P30CA008748-43), NHMRC | Molecular Epidemiology of... (400281), NIH | Genetic Epidemiology of O... (5K07CA143047-02), NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NHMRC | Epidemiology of Chronic D... (209057), NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NHMRC | Towards cancer control: P... (199600), NIH | COLLABORATIVE STUDY OF OV... (5R01CA058598-05),...

    RNA editing in mammals is a form of post-transcriptional modification in which adenosine is converted to inosine by the adenosine deaminases acting on RNA (ADAR) family of enzymes. Based on evidence of altered ADAR expression in epithelial ovarian cancers (EOC), we hypo...

  • publication . Article . 2016
    Open Access English
    Authors:
    Jolanta Lissowska; Sara Olson; Zachary Fogarty; yian Chen; Peter Kraft; Hui-Yi Lin; Alvaro Monteiro; Jeremy Chien; Stacey Winham;
    Publisher: Impact Journals LLC
    Project: CIHR , NIH | USC COMPREHENSIVE CANCER ... (3P30CA014089-17S1), NIH | CASE-CONTROL STUDY OF OVA... (1R01CA061132-01), NIH | Genes, Hormones &Environm... (5R01CA054419-14), NIH | MOLECULAR EPIDEMIOLOGY OF... (5R01CA076016-04), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN025403-000), NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NIH | COLLABORATIVE STUDY OF OV... (5R01CA058598-05), NIH | CANCER CENTER SUPPORT GRA... (3P30CA072720-07S2), NIH | OVARIAN CANCER RISK AND S... (5K07CA080668-06),...

    Background: Genome-wide association studies have identified several common susceptibility alleles for epithelial ovarian cancer (EOC). To further understand EOC susceptibility, we examined previously ungenotyped candidate variants, including uncommon variants and those ...

  • publication . Article . 2015
    Open Access English
    Authors:
    Jolanta Lissowska; Giske Ursin; Christine Friedenreich; Fredrick Schumacher; Sara Olson; Veronica Setiawan; Peter Kraft;
    Publisher: Public Library of Science
    Project: NIH | Epidemiology of Ovarian C... (5R01CA087538-02), NIH | ENDOMETRIAL CANCER AND PO... (1R01CA075977-01), NIH | A Whole Genome Admixture ... (3R01CA063464-09S1), NIH | Role of Genetic and Lifes... (1R01CA098346-01A1), NIH | CALIFORNIA TEACHERS STUDY (5R01CA077398-09), NIH | Genome-Wide Association S... (5R01CA134958-02), NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NIH | BREAST CANCER AND THE BIR... (N01HD023166-008), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN067009-004), NIH | GENES AND THE ESTROGEN EF... (1R01CA091019-01A1),...

    Genome-wide association studies (GWAS) have identified common variants that predispose individuals to a higher body mass index (BMI), an independent risk factor for endometrial cancer. Composite genotype risk scores (GRS) based on the joint effect of published BMI risk ...

  • publication . Article . Other literature type . 2016
    Open Access
    Authors:
    Alice Lee; Penelope Webb; Allan Jensen; Signe Marie Jensen; Estrid Høgdall; Susan Ramus; Stacey Winham; Usha Menon; Lambertus Kiemeney;
    Publisher: Elsevier BV
    Project: NIH | Training Grant in Genomic... (5T32ES013678-05), NHMRC | Molecular Epidemiology of... (400281), NIH | Genetic Epidemiology of O... (5K07CA143047-02), NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MOLECULAR EPIDEMIOLOGY OF... (5R01CA076016-04), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN025403-000), NIH | CASE CONTROL STUDY OF OVA... (5R01CA074850-05), NIH | NORTHERN CALIFORNIA COOPE... (5U01CA069417-02), NIH | DNA POLYMORPHISMS IN OVAR... (5R01CA080742-04),...

    PURPOSE: Socioeconomic status (SES) is a known predictor of survival for several cancers and it has been suggested that SES differences affecting tumour stage at diagnosis may be the most important explanatory factor for this. However, only a limited number of studies h...

  • publication . Article . 2014
    Open Access
    Authors:
    Jolanta Lissowska; Carlotta Sacerdote; Fredrick Schumacher; Christine Friedenreich; Maxine Chen; Sara Olson; Veronica Setiawan; Marta Crous-Bou; Irene Orlow;
    Publisher: Public Library of Science (PLoS)
    Project: NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | GENETIC SUSCEPTIBILITY TO... (5R01CA082838-04), NIH | Genome-Wide Association S... (5R01CA134958-02), NIH | Genetic Variation in Estr... (5R03CA128008-02), NIH | Molecular Epidemiology of... (1R01CA105212-01A1), NIH | Training Program in Cance... (5T32CA009001-38), NIH | DIET, HORMONES AND RISK O... (3P01CA087969-03S1), CIHR , NIH | RESEARCH IN CANCER EPIDEM... (3R35CA039779-09S1),...

    Endometrial cancer (EC) contributes substantially to total burden of cancer morbidity and mortality in the United States. Family history is a known risk factor for EC, thus genetic factors may play a role in EC pathogenesis. Three previous genome-wide association studie...

  • publication . Article . 2019
    Open Access English
    Authors:
    Kim, S.; Wang, M.; Tyrer, J. P.; Jensen, A.; Wiensch, A.; Liu, G.; Lee, A. W.; Ness, R. B.; Salvatore, M.; Tworoger, S. S.; ...
    Project: NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NIH | PCOS, Type II diabetes an... (5K22CA193860-03), NIH | Training Grant in Genomic... (5T32ES013678-05), NIH | Steroid Hormone Genes and... (5R01CA112523-03), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | SURVEILLANCE, EPIDEMIOLOG... (N01CN067001-000), NIH | MOLECULAR EPIDEMIOLOGY OF... (5R01CA076016-04), NIH | Long Term Multidisciplina... (5UM1CA186107-05), NIH | RISK FACTORS AND PROGNOST... (1R01CA061107-01), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01PC067010-000),...

    As a follow-up to genome-wide association analysis of common variants associated with ovarian carcinoma (cancer), this study considers seven well-known ovarian cancer risk factors and their interactions with 28 genome-wide significant common genetic variants. The intera...

  • publication . Article . 2018
    Open Access English
    Authors:
    Dixon-Suen, Suzanne C.; Nagle, Christina M.; Thrift, Aaron P.; Pharoah, Paul D. P.; Ewing, Ailith; Pearce, Celeste Leigh; Zheng, Wei; Chenevix-Trench, Georgia; Fasching, Peter A.; Beckmann, Matthias W.; ...
    Publisher: Nature Publishing Group UK
    Project: NIH | USC CANCER CENTER EPIDEMI... (2P01CA017054-17), NIH | HEREDITARY BREAST CANCER-... (5R01CA058860-02), NIH | Ovarian Cancer and Gonado... (5R03CA115195-02), NIH | ROSWELL PARK MEMORIAL INS... (5P30CA016056-17), NIH | Phytoestrogens, alcohol, ... (1K07CA095666-01A1), NIH | PRE SURGICAL O6 BENZYLGUA... (3M01RR000056-38S3), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN067010-000), NIH | MOUSE GENETICS (2P30CA008748-43), NHMRC | Generating the evidence t... (1073898), EC | COGS (223175),...

    Background:\ud \ud Observational studies suggest greater height is associated with increased ovarian cancer risk, but cannot exclude bias and/or confounding as explanations for this. Mendelian randomisation (MR) can provide evidence which may be less prone to bias.\ud M...

12 research outcomes, page 1 of 2
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