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5 research outcomes, page 1 of 1
  • publication . Article . 2019
    Open Access English
    Authors:
    Tao Dao; Sung Soo Mun; Andrew C. Scott; Casey A. Jarvis; Tatyana Korontsvit; Zhiyuan Yang; Lianxing Liu; Martin G. Klatt; Manuel Guerreiro; Annamalai Selvakumar; ...
    Publisher: Taylor & Francis
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MONOCLONAL ANTIBODY THERA... (5P01CA033049-13), NIH | Biology of Alpha Particle... (2R01CA055349-16A2)

    ABSTRACT Depletion of T regulatory cells (Tregs) in the tumor microenvironment is a promising cancer immunotherapy strategy. Current approaches for depleting Tregs are limited by lack of specificity and concurrent depletion of anti-tumor effector T cells. The transcript...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Alidori, Simone; Thorek, Daniel L. J.; Beattie, Bradley J.; Ulmert, David; Almeida, Bryan Aristega; Monette, Sebastien; Scheinberg, David A.; McDevitt, Michael R.;
    Publisher: Public Library of Science (PLoS)
    Project: NIH | Weill Cornell/Rockefeller... (5T32GM007739-30), NIH | Improving therapy of glio... (5R01CA166078-04), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | The Roles of Microglia an... (1F31CA167863-01), NIH | MONOCLONAL ANTIBODY THERA... (5P01CA033049-13), NIH | Biology of Alpha Particle... (2R01CA055349-16A2), NIH | Novel Nano-Constructs to ... (1R21CA128406-01), NIH | ANIMAL NMR AND RADIONUCLI... (3R24CA083084-04S1)

    Nanomedicine rests at the nexus of medicine, bioengineering, and biology with great potential for improving health through innovation and development of new drugs and devices. Carbon nanotubes are an example of a fibrillar nanomaterial poised to translate into medical p...

  • publication . Article . Other literature type . 2016
    Open Access Russian
    Authors:
    Ke Xu; Elliott Brea;
    Project: NIH | The Roles of Microglia an... (1F31CA167863-01), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Novel Nano-Constructs to ... (1R21CA128406-01), NIH | Improving therapy of glio... (5R01CA166078-04), NIH | MONOCLONAL ANTIBODY THERA... (5P01CA033049-13), NIH | Biology of Alpha Particle... (2R01CA055349-16A2), NIH | ANIMAL NMR AND RADIONUCLI... (3R24CA083084-04S1)

    Single-wall carbon nanotubes present unique opportunities for drug delivery, but have not advanced into the clinic. Differential nanotube accretion and clearance from critical organs have been observed, but the mechanism not fully elucidated. The liver has a complex cel...

  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    McDevitt, Michael R.; Thorek, Daniel L. J.; Hashimoto, Takeshi; Gondo, Tatsuo; Veach, Darren R.; Sharma, Sai Kiran; Kalidindi, Teja Muralidhar; Abou, Diane S.; Watson, Philip A.; Beattie, Bradley J.; ...
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | The Roles of Microglia an... (1F31CA167863-01), NIH | RATIONAL DESIGN OF PROSTA... (5P50CA092629-10), NIH | Regional Oncology Researc... (3P30CA006973-53S2), NIH | Shared Instrument: Focus ... (1S10RR020892-01), NIH | MONOCLONAL ANTIBODY THERA... (5P01CA033049-13), NIH | Biology of Alpha Particle... (2R01CA055349-16A2), NIH | NanoSPECT/CT for Oncology... (1S10RR028889-01), NIH | Prospective validation of... (5R01CA160816-02), NIH | Improving prostate cancer... (5R01CA175491-04),...

    Radionuclides that emit alpha particles (charged helium nuclei) are currently used clinically to treat cancers including prostate cancer. Here, the authors combine a humanized antibody to an alpha particle emitter, specifically to target a downstream effector of the and...

  • publication . Article . 2003
    Open Access English
    Authors:
    Deckert, P M; Renner, C; Cohen, L S; Jungbluth, A; Ritter, G; Bertino, J R; Old, L J; Welt, S;
    Publisher: Nature Publishing Group
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MONOCLONAL ANTIBODY THERA... (5P01CA033049-13)
5 research outcomes, page 1 of 1
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