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6 research outcomes, page 1 of 1
  • publication . Article . 2017
    Open Access
    Authors:
    Joshua K. Sabari; Evan D. Siau; Alexander Drilon;
    Publisher: Impact Journals, LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Cancer Chemotherapy Train... (5T32CA009207-29)
  • publication . Other literature type . Article . 2019
    Open Access
    Authors:
    Harihar Basnet; Lin Tian; Karuna Ganesh; Yun-Han Huang; Danilo G Macalinao; Edi Brogi; Lydia WS Finley; Joan Massagué;
    Publisher: eLife Sciences Publications, Ltd
    Project: NIH | Weill Cornell/Rockefeller... (5T32GM007739-30), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Investigating L1CAM-depen... (1K08CA230213-01), NIH | Mechanisms of Metastasis ... (5P01CA094060-07), NIH | Mechanisms of Escape from... (5F30CA203238-03), NIH | Cancer Chemotherapy Train... (5T32CA009207-29)

    Metastasis-initiating cells dynamically adapt to the distinct microenvironments of different organs, but these early adaptations are poorly understood due to the limited sensitivity of in situ transcriptomics. We developed fluorouracil-labeled RNA sequencing (Flura-seq)...

  • publication . Article . Other literature type . 2018
    Open Access
    Authors:
    Emiliano Calvo; Sarina Piha-Paul; Sherene Loi; Victor Moreno;
    Publisher: Springer Science and Business Media LLC
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | ERBB2 TARGETED ANTITUMOR ... (5R01CA080195-04), NIH | Cancer Center Support (CO... (3P30CA016672-41S4), NIH | Understanding Long Tail D... (5R01CA204749-03), NIH | Informatics to enable rou... (5U01CA180964-02), NIH | Cancer Chemotherapy Train... (5T32CA009207-29), NIH | SPORE in Breast Cancer (3P50CA098131-15S1), NIH | Center for Clinical and T... (4UL1TR000371-10), NIH | USC COMPREHENSIVE CANCER ... (3P30CA014089-17S1)

    Somatic mutations of ERBB2 and ERBB3 (which encode HER2 and HER3, respectively) are found in a wide range of cancers. Preclinical modelling suggests that a subset of these mutations lead to constitutive HER2 activation, but most remain biologically uncharacterized. Here...

  • publication . Preprint . 2019
    Open Access
    Authors:
    Ganesh, Karuna; Wu, Chao; O’Rourke, Kevin P.; Adileh, Mohammad; Szeglin, Bryan C.; Wasserman, Isaac; Marco, Michael R.; Shady, Maha; Zheng, Youyun; Karthaus, Wouter R.; ...
    Publisher: Cold Spring Harbor Laboratory
    Project: NIH | Defining the Role of ERG ... (5R01CA193837-02), NIH | Weill Cornell/Rockefeller... (5T32GM007739-30), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Mechanisms of Metastasis ... (5P01CA094060-07), NIH | Modeling metastatic color... (5F30CA200110-02), NIH | Understanding Resistance ... (4R01CA155169-05), NIH | Investigating L1CAM-depen... (1K08CA230213-01), NIH | Cancer Chemotherapy Train... (5T32CA009207-29), NIH | Translational Research in... (5T32CA160001-03), NIH | CANCER EDUCATION PROGRAM (2R25CA020449-14),...

    <jats:title>Abstract</jats:title><jats:p>Rectal cancer (RC) is a challenging disease to treat that requires chemotherapy, radiation, and surgery to optimize outcomes for individual patients. No accurate model of RC exists to answer fundamental research questions relevan...

  • publication . Article . 2019
    Open Access
    Authors:
    Suzawa, Ken; Offin, Michael; Schoenfeld, Adam J.; Plodkowski, Andrew J.; Odintsov, Igor; Lu, Daniel; Lockwood, William W.; Arcila, Maria E.; Rudin, Charles M.; Drilon, Alexander; ...
    Publisher: American Society of Clinical Oncology (ASCO)
    Project: NIH | Mechanisms and Modulators... (5P01CA129243-07), NIH | Cancer Chemotherapy Train... (5T32CA009207-29), NIH | MOUSE GENETICS (2P30CA008748-43)
  • publication . Article . 2016
    Open Access English
    Authors:
    Alison M. Schram; Alexia Iasonos; David M. Hyman;
    Publisher: American Society of Clinical Oncology
    Project: NIH | MOUSE GENETICS (2P30CA008748-43), NIH | Cancer Chemotherapy Train... (5T32CA009207-29)
6 research outcomes, page 1 of 1
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