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  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Piro Lito; Piro Lito; Gouri Nanjangud; Trang Thi Mai; Yaohua Xue; Yaohua Xue; G. J. Riely; Ulrika Stierner; Alberto Vides; Fabiola Cechhi; ...
    Project: NIH | Elucidating the regulatio... (5K08CA191082-02), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MSKCC Pilot Center for Pr... (5U54OD020355-04), NIH | Weill Cornell/Rockefeller... (5T32GM007739-30)

    The principles that govern the evolution of tumors exposed to targeted therapy are poorly understood. Here we modeled the selection and propagation of an amplification in the BRAF oncogene (BRAFamp) in patient-derived tumor xenografts (PDXs) that were treated with a dir...

1 research outcomes, page 1 of 1