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6 research outcomes, page 1 of 1
  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Liu, Gang; Mukherjee, Bhramar; Lee, Seunggeun; Lee, Alice W; Wu, Anna H; Bandera, Elisa V; Jensen, Allan; Rossing, Mary Anne; Moysich, Kirsten B; Chang-Claude, Jenny; ...
    Publisher: Oxford University Press
    Project: NIH | Follow-up of Ovarian Canc... (3U19CA148112-04S1), NIH | Mayo Comprehensive Cancer... (3P30CA015083-37S2), NIH | RISK FACTORS AND PROGNOST... (1R01CA061107-01), NIH | CANCER CENTER SUPPORT GRA... (3P30CA072720-07S2), NIH | MOLECULAR EPIDEMIOLOGY OF... (5R01CA076016-04), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN025403-000), NIH | MOUSE GENETICS (2P30CA008748-43), NSF | Set based tests for genet... (1406712), NHMRC | Molecular Epidemiology of... (400281), NHMRC | Towards cancer control: P... (199600),...

    There have been recent proposals advocating the use of additive gene-environment interaction instead of the widely used multiplicative scale, as a more relevant public health measure. Using gene-environment independence enhances statistical power for testing multiplicat...

  • publication . Article . Other literature type . 2018
    Open Access English
    Authors:
    Kelemen, Linda E; Earp, Madalene; Fridley, Brooke L; Chenevix-Trench, Georgia; Australian Ovarian Cancer Study Group,; Fasching, Peter A; Beckmann, Matthias W; Ekici, Arif B; Hein, Alexander; Lambrechts, Diether; ...
    Publisher: eScholarship, University of California
    Project: NIH | MOLECULAR EPIDEMIOLOGY OF... (5R01CA076016-04), NIH | SURVEILLANCE EPIDEMIOLOGY... (N01CN025403-000), NIH | Epidemiology of Ovarian C... (5R01CA087538-02), NIH | INTERNAL COUNCIL FOR TOBA... (1R01CA087696-01), NIH | Obesity in ovarian cancer... (5K22CA138563-02), NIH | Haplotype-Based Genome Sc... (1R01CA114343-01A2), NIH | Risk Factors for Breast C... (5R01CA050385-18), NIH | The Progesterone Receptor... (1R03CA113148-01), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | MHC-Restricted and MHC-No... (1P50CA159981-01A1),...

    95% CI = 1.03–1.24

  • publication . Article . 2016
    Open Access
    Authors:
    Permuth, J. B.; Reid, B.; Earp, M.; Chen, Y. A.; Monteiro, A. N. A.; Chen, Z.; Chenevix-Trench, G.; Fasching, P. A.; Beckmann, M. W.; Lambrechts, D.; ...
    Project: NIH | Epidemiology of Ovarian C... (5R01CA087538-02), NIH | Premenopausal Hormone Lev... (5R01CA067262-08), NIH | MOUSE GENETICS (2P30CA008748-43), NHMRC | Molecular Epidemiology of... (400281), NIH | Genetic Epidemiology of O... (5K07CA143047-02), NIH | ESTROGEN, DIET, GENETICS ... (5R01CA083918-04), NHMRC | Epidemiology of Chronic D... (209057), NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NHMRC | Towards cancer control: P... (199600), NIH | COLLABORATIVE STUDY OF OV... (5R01CA058598-05),...

    RNA editing in mammals is a form of post-transcriptional modification in which adenosine is converted to inosine by the adenosine deaminases acting on RNA (ADAR) family of enzymes. Based on evidence of altered ADAR expression in epithelial ovarian cancers (EOC), we hypo...

  • publication . Article . Other literature type . 2017
    Open Access English
    Authors:
    Glubb, Dylan M; Johnatty, Sharon E; Quinn, Michael CJ; O'Mara, Tracy A; Tyrer, Jonathan; Gao, Bo; Fasching, Peter A; Beckmann, Matthias W; Lambrechts, Diether; Vergote, Ignace; ...
    Publisher: Impact Journals
    Project: EC | COGS (223175), NIH | Inflammation and Ovarian ... (5R01CA095023-03), NIH | Regulatory T Cell Functio... (5R01CA126841-04), NIH | Discovery Expansion and R... (5U19CA148065-04), NHMRC | Australasian Biospecimen ... (628903), NIH | MOLECULAR EPIDEMIOLOGY OF... (5R01CA076016-04), NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NHMRC | Towards cancer control: P... (199600), NIH | COLLABORATIVE STUDY OF OV... (5R01CA058598-05), NIH | The Mitochondrial Genome ... (5R01CA149429-05),...

    We previously identified associations with ovarian cancer outcome at five genetic loci. To identify putatively causal genetic variants and target genes, we prioritized two ovarian outcome loci (1q22 and 19p12) for further study. Bioinformatic and functional genetic anal...

  • publication . Article . Preprint . Other literature type . 2019
    Open Access English
    Authors:
    Jiang, Xia; Finucane, Hilary K; Schumacher, Fredrick R; Schmit, Stephanie L; Tyrer, Jonathan; Han, Younghun; Michailidou, Kyriaki; Lesseur, Corina; Kuchenbaecker, Karoline B; Dennis, Joe; ...
    Publisher: Nature Publishing Group
    Project: NIH | The Vanderbilt Institute ... (6UL1TR000445-11), NIH | Discovery and verificatio... (5R01CA189184-04), NHMRC | Markers of androgen actio... (450104), NIH | The Mitochondrial Genome ... (5R01CA149429-05), NIH | Cancer Risk Reduction and... (2R37CA070867-12), NIH | Genes contributing for ni... (5R01DA017932-07), NIH | Consortium Study to Ident... (5R01CA148667-05), NIH | Career Development (Ingle... (5P50CA116201-08), NIH | Breast &prostate cancer &... (1U01CA098216-01), NIH | Characterizing Genetic Su... (5U01CA098710-06),...

    Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association study summary statistics across six cancer types based on a total of 296,215 cases and 301,319 controls of Europ...

  • publication . Article . Other literature type . 2016
    Open Access English
    Authors:
    Thilo Dörk; Stuart MacGregor; Sara Olson; Anna Jakubowska; Liisa M Pelttari; Susan Ramus; Tomasz Kluz; Ian Campbell; Jolanta Lissowska; Yi Lu; ...
    Publisher: eScholarship, University of California
    Project: NIH | Mayo Clinic SPORE in Ovar... (3P50CA136393-05S1), NHMRC | Towards cancer control: P... (199600), NIH | COLLABORATIVE STUDY OF OV... (5R01CA058598-05), NIH | Steroid Hormone Genes and... (5R01CA112523-03), NIH | Regulatory T Cell Functio... (5R01CA126841-04), NIH | HEREDITARY BREAST CANCER-... (5R01CA058860-02), NIH | Ovarian Cancer and Gonado... (5R03CA115195-02), NIH | Premenopausal Hormone Lev... (5R01CA067262-08), NIH | The Mitochondrial Genome ... (5R01CA149429-05), NIH | MOUSE GENETICS (2P30CA008748-43),...

    BACKGROUND: In vitro and observational epidemiological studies suggest that vitamin D may play a role in cancer prevention. However, the relationship between vitamin D and ovarian cancer is uncertain, with observational studies generating conflicting findings. A potenti...

6 research outcomes, page 1 of 1
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