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  • publication . Article . Other literature type . 2017
    Intrathymic injection of hematopoietic progenitor cells establishes functional T cell development in a mouse model of severe combined immunodeficiency
    Open Access English
    Authors:
    Marcel R.M. van den Brink; Andrea Z. Tuckett; Richard J. O'Reilly; Johannes L. Zakrzewski; Raymond H. Thornton;
    doi: 10.1186/s13045-017-0478-z
    pmc: PMC5432974
    pmid: 28511686
    Publisher: BioMed Central
    Project: NIH | Mucosal Immunity and Micr... (9R01AI100288-06A1), NIH | MOUSE GENETICS (2P30CA008748-43), NIH | The role of autophagy gen... (1R01HL123340-01A1), NIH | Strategies to enhance thy... (1K08CA160659-01), EC | THYMISTEM (602587), NIH | Strategies to enhance imm... (5R01HL069929-12), NIH | MARROW TRANSPLANTATION IN... (5P01CA023766-14), NIH | IL-22 in Thymic Regenerat... (5R01AI101406-02)

    Background Even though hematopoietic stem cell transplantation can be curative in patients with severe combined immunodeficiency, there is a need for additional strategies boosting T cell immunity in individuals suffering from genetic disorders of lymphoid development. ...

1 research outcomes, page 1 of 1